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The emergence of novel pathogens and zoonotic diseases like the SARS-CoV-2 have underlined the need for developing novel diagnosis and intervention pipelines that can learn rapidly from small amounts of labeled data. Combined with…

The efficacy of deep learning-based Computer-Aided Diagnosis (CAD) methods for skin diseases relies on analyzing multiple data modalities (i.e., clinical+dermoscopic images, and patient metadata) and addressing the challenges of multi-label…

计算机视觉与模式识别 · 计算机科学 2024-09-20 Yuan Zhang , Yutong Xie , Hu Wang , Jodie C Avery , M Louise Hull , Gustavo Carneiro

Survival prediction plays a crucial role in assisting clinicians with the development of cancer treatment protocols. Recent evidence shows that multimodal data can help in the diagnosis of cancer disease and improve survival prediction.…

图像与视频处理 · 电气工程与系统科学 2023-11-14 Ruiquan Ge , Xiangyang Hu , Rungen Huang , Gangyong Jia , Yaqi Wang , Renshu Gu , Changmiao Wang , Elazab Ahmed , Linyan Wang , Juan Ye , Ye Li

Discovering genes with similar functions across diverse biomedical contexts poses a significant challenge in gene representation learning due to data heterogeneity. In this study, we resolve this problem by introducing a novel model called…

机器学习 · 计算机科学 2023-10-05 Tianyu Liu , Yuge Wang , Rex Ying , Hongyu Zhao

As the volume of digital image data increases, the effectiveness of image classification intensifies. This study introduces a robust multi-label classification system designed to assign multiple labels to a single image, addressing the…

计算机视觉与模式识别 · 计算机科学 2025-01-06 Haixu Liu , Penghao Jiang , Zerui Tao

Whole slide images are the foundation of digital pathology for the diagnosis and treatment of carcinomas. Writing pathology reports is laborious and error-prone for inexperienced pathologists. To reduce the workload and improve clinical…

计算机视觉与模式识别 · 计算机科学 2024-06-28 Pingyi Chen , Honglin Li , Chenglu Zhu , Sunyi Zheng , Zhongyi Shui , Lin Yang

In the genome biology research, regulatory genome modeling is an important topic for many regulatory downstream tasks, such as promoter classification, transaction factor binding sites prediction. The core problem is to model how regulatory…

基因组学 · 定量生物学 2021-11-04 Shentong Mo , Xi Fu , Chenyang Hong , Yizhen Chen , Yuxuan Zheng , Xiangru Tang , Zhiqiang Shen , Eric P Xing , Yanyan Lan

Automated whole slide image (WSI) tagging has become a growing demand due to the increasing volume and diversity of WSIs collected nowadays in histopathology. Various methods have been studied to classify WSIs with single tags but none of…

计算机视觉与模式识别 · 计算机科学 2019-07-05 Weijian Li , Viet-Duy Nguyen , Haofu Liao , Matt Wilder , Ke Cheng , Jiebo Luo

Multi-label image recognition is a task that predicts a set of object labels in an image. As the objects co-occur in the physical world, it is desirable to model label dependencies. Previous existing methods resort to either recurrent…

计算机视觉与模式识别 · 计算机科学 2019-10-01 Qing Li , Xiaojiang Peng , Yu Qiao , Qiang Peng

Pre-trained large language models(LLMs) have attracted increasing attention in biomedical domains due to their success in natural language processing. However, the complex traits and heterogeneity of multi-sources genomics data pose…

In histopathology, intelligent diagnosis of Whole Slide Images (WSIs) is essential for automating and objectifying diagnoses, reducing the workload of pathologists. However, diagnostic models often face the challenge of forgetting…

计算机视觉与模式识别 · 计算机科学 2025-03-26 Weixi Zheng , Aoling Huang , Jingping Yuan , Haoyu Zhao , Zhou Zhao , Yongchao Xu , Thierry Géraud

Accurate classification of pediatric central nervous system tumors remains challenging due to histological complexity and limited training data. While pathology foundation models have advanced whole-slide image (WSI) analysis, they often…

Lung adenocarcinoma (LUAD) is characterized by substantial genetic heterogeneity, posing challenges in identifying reliable biomarkers for improved diagnosis and treatment. Tumor Mutational Burden (TMB) has traditionally been regarded as a…

应用统计 · 统计学 2024-11-08 Shaofei Zhao , Siming Huang , Kexuan Li , Weiyu Zhou , Lingli Yang , Shige Wang

Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a…

Cancer is a heterogeneous disease with different combinations of genetic and epigenetic alterations driving the development of cancer in different individuals. While these alterations are believed to converge on genes in key cellular…

定量方法 · 定量生物学 2015-03-31 Mark D. M. Leiserson , Hsin-Ta Wu , Fabio Vandin , Benjamin J. Raphael

It's a meaningful and attractive topic to build a general and inclusive segmentation model that can recognize more categories in various scenarios. A straightforward way is to combine the existing fragmented segmentation datasets and train…

计算机视觉与模式识别 · 计算机科学 2023-02-28 Qiang Zhou , Yuang Liu , Chaohui Yu , Jingliang Li , Zhibin Wang , Fan Wang

Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy…

Predicting the response of a patient to a cancer treatment is of high interest. Nonetheless, this task is still challenging from a medical point of view due to the complexity of the interaction between the patient organism and the…

计算机视觉与模式识别 · 计算机科学 2024-08-09 Bilel Guetarni , Feryal Windal , Halim Benhabiles , Mahfoud Chaibi , Romain Dubois , Emmanuelle Leteurtre , Dominique Collard

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

计算机视觉与模式识别 · 计算机科学 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

计算机视觉与模式识别 · 计算机科学 2025-08-05 Anwai Archit , Constantin Pape
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