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Intensity-modulated proton therapy (IMPT) offers superior dose conformity with reduced exposure to surrounding healthy tissues compared to conventional photon therapy. Improving IMPT delivery efficiency reduces motion-related uncertainties,…

医学物理 · 物理学 2025-04-15 Ya-Nan Zhu , Nimita Shinde , Bowen Lin , Hao Gao

Background: Multi-collimator proton minibeam radiation therapy (MC-pMBRT) has recently emerged as a versatile technique for dose shaping, enabling peak-valley dose patterns in organs-at-risk (OAR) while maintaining a uniform dose…

医学物理 · 物理学 2025-02-25 Nimita Shinde , Weijie Zhang , Yuting Lin , Hao Gao

We aim to investigate the feasibility of online monitoring of irradiation time (IRT) and scan time for FLASH radiotherapy using a pixelated semiconductor detector. Measurements of the time structure of FLASH irradiations were performed…

Flattening filter free (FFF) beams due to their non-uniformity, are sub-optimal for larger field sizes. The purpose of this study was to investigate the incident electron beam distributions that would produce flat FFF beams without the use…

医学物理 · 物理学 2015-06-16 Sergei Zavgorodni

Photonic integration, advanced functionality, reconfigurability, and high RF performance are key features in integrated microwave photonic systems that are still difficult to achieve simultaneously. In this work, we demonstrate an…

应用物理 · 物理学 2023-03-01 Gaojian Liu , Kaixuan Ye , Okky Daulay , Qinggui Tan , Hongxi Yu , David Marpaung

We report a fully integrated microwave photonic passband filter on a silicon photonic chip. The on-chip integrated microwave photonic filter (IMPF) consists of a high-speed phase modulator (PM), a thermally tunable high-Q micro-disk…

应用物理 · 物理学 2018-08-15 Weifeng Zhang , Jianping Yao

Stereotactic body radiotherapy (SBRT) is characterized by delivering a high amount of dose in a short period of time. In SBRT the dose is delivered using open fields (e.g., beam's-eye-view) known as "apertures". Mathematical methods can be…

医学物理 · 物理学 2015-06-15 Hamed Yarmand , David Craft

Visible-spectrum photonic integrated circuits (PICs) present compact and scalable solutions for emerging technologies including quantum computing, biosensing, and virtual/augmented reality. Realizing their full potential requires the…

A prototype plastic scintillating fibre based beam profile monitor was tested at the Heidelberg Ion Therapy Centre / \textit{Heidelberg Ionenstrahl Therapiezentrum} (HIT) in 2016 to determine its beam property reconstruction performance and…

仪器与探测器 · 物理学 2018-06-27 B. D. Leverington , M. Dziewiecki , L. Renner , R. Runze

A research complex for aerospace radiation effects research has been proposed in Harbin Institute of Technology. Its core part is a proton accelerator complex, which consists of a 10 MeV injector, a 300 MeV synchrotron and beam transport…

加速器物理 · 物理学 2016-05-27 Yuwen An , Hongfei Ji , Sheng Wang , Liangsheng Huang

Conventional planning objectives in optimization of intensity-modulated radiotherapy treatment (IMRT) plans are designed to minimize the violation of dose-volume histogram (DVH) thresholds using penalty functions. Although successful in…

医学物理 · 物理学 2023-07-19 Lovisa Engberg , Kjell Eriksson , Anders Forsgren , Björn Hårdemark

Controlling the in-band co-polarization scattering of the antenna while maintaining its radiation performance is crucial for the low observable platform. Thus, this paper studies the in-band co-polarization scattering beam scanning of…

应用物理 · 物理学 2023-09-27 Binchao Zhang , Fan Yang , Shenheng Xu , Maokun Li , Cheng Jin

Operating atom-interferometer gyroscopes outside a laboratory environment is challenging primarily owing to the instability of laser systems. To enhance the thermal stability of free-space laser systems, a compact laser system using fiber…

Subwavelength grating micro-polarizer arrays, as a type of focal plane division simultaneous detection method, are significantly advancing the development and practical application of polarization imaging technology. Based on the…

光学 · 物理学 2024-10-17 Tianshi Lu , Fuyuan Deng , Yufeng Wei , Zhipeng Zeng , Xinghui Li

Purpose: To develop a single-shot multi-slice T1 mapping method by combing simultaneous multi-slice (SMS) excitations, single-shot inversion-recovery (IR) radial fast low-angle shot (FLASH) and a nonlinear model-based reconstruction method.…

Ultra-high dose rate electron sources require dose rate independent dosimeters and a calibrated dose control system for accurate delivery. In this study, we developed a single-pulse dose monitoring and a real-time dose-based control system…

A novel and simple model is proposed for the measurement of the linewidth enhancement factor (LEF) {\alpha} of multiwavelengths semiconductor laser. It is based on the suppression characteristics of an arbitrary mode while other modes are…

光学 · 物理学 2011-06-21 Samir K Mondal

Purpose: To improve target coverage and reduce the dose in the surrounding organs-at-risks (OARs), we developed an image-guided treatment method based on a precomputed library of treatment plans controlled and delivered in real-time.…

医学物理 · 物理学 2022-11-02 Valentin Hamaide , Kevin Souris , Damien Dasnoy , Francois Glineur , Benoit Macq

We implement an integrated multi-electrode array on a silicon-nitride-based photonic integrated circuit for ex-vivo retinal characterization via optical stimulation. The interrogation beam formers, based on curved grating emitters and…

Objective: Proton spot-scanning arc therapy (ARC) is an emerging modality that can improve the high-dose conformity to targets compared with standard intensity-modulated proton therapy (IMPT). However, the efficient treatment delivery of…