中文
相关论文

相关论文: Phenotype control and elimination of variables in …

200 篇论文

When observational data is available from practical studies and a directed cyclic graph for how various variables affect each other is known based on substantive understanding of the process, we consider a problem in which a control plan of…

统计方法学 · 统计学 2012-06-26 Manabu Kuroki , Zhihong Cai

Boolean networks (BNs) are widely used to model the qualitative dynamics of biological systems. Besides the logical rules determining the evolution of each component with respect to the state of its regulators, the scheduling of component…

计算机科学中的逻辑 · 计算机科学 2019-06-03 Thomas Chatain , Stefan Haar , Juraj Kolčák , Loïc Paulevé , Aalok Thakkar

Boolean networks are special types of finite state time-discrete dynamical systems. A Boolean network can be described by a function from an n-dimensional vector space over the field of two elements to itself. A fundamental problem in…

定量方法 · 定量生物学 2013-07-03 Yi Ming Zou

We consider epidemic extinction in finite networks with broad variation in local connectivity. Generalizing the theory of large fluctuations to random networks with a given degree distribution, we are able to predict the most probable, or…

适应与自组织系统 · 物理学 2016-07-07 Jason Hindes , Ira B. Schwartz

For years, we have been building models of gene regulatory networks, where recent advances in molecular biology shed some light on new structural and dynamical properties of such highly complex systems. In this work, we propose a novel…

适应与自组织系统 · 物理学 2009-09-30 Christian Darabos , Marco Tomassini , Mario Giacobini

The generating functional method is employed to investigate the synchronous dynamics of Boolean networks, providing an exact result for the system dynamics via a set of macroscopic order parameters. The topology of the networks studied and…

无序系统与神经网络 · 物理学 2015-05-28 Alexander Mozeika , David Saad

Ecological networks such as plant-pollinator systems and food webs vary in space and time. This variability includes fluctuations in global network properties such as total number and intensity of interactions but also in the local…

定量方法 · 定量生物学 2022-12-23 Tancredi Caruso , Giulio Virginio Clemente , Matthias C Rillig , Diego Garlaschelli

Boolean networks are one of the most studied discrete models in the context of the study of gene expression. In order to define the dynamics associated to a Boolean network, there are several \emph{update schemes} that range from parallel…

形式语言与自动机理论 · 计算机科学 2019-01-29 Eric Goles , Pedro Montealegre , Martín Ríos Wilson

Controlling a complex network is of great importance in many applications. The network can be controlled by inputting external control signals through some selected nodes, which are called input nodes. Previous works found that the majority…

社会与信息网络 · 计算机科学 2019-10-23 Xizhe Zhang , Qian Li

To model biological systems using networks, it is desirable to allow more than two levels of expression for the nodes and to allow the introduction of parameters. Various modeling and simulation methods addressing these needs using Boolean…

分子网络 · 定量生物学 2014-04-23 Yi Ming Zou

From gene regulatory networks to mutualistic networks, controlling a single node in the network topology can transform these complex dynamical systems from undesirable states to desirable ones. Corresponding methods have been well-studied…

动力系统 · 数学 2025-02-26 Nan Dong , An Zeng , Honggang Li

Random Boolean networks, originally invented as models of genetic regulatory networks, are simple models for a broad class of complex systems that show rich dynamical structures. From a biological perspective, the most interesting networks…

无序系统与神经网络 · 物理学 2009-11-07 Joshua E. S. Socolar , Stuart A. Kauffman

An econometric or statistical model may undergo a marginal gain if we admit a new variable to the model, and a marginal loss if we remove an existing variable from the model. Assuming equality of opportunity among all candidate variables,…

机器学习 · 统计学 2020-03-16 Xingwei Hu

This paper investigates the identification and inference of treatment effects in randomized controlled trials with social interactions. Two key network features characterize the setting and introduce endogeneity: (1) latent variables may…

计量经济学 · 经济学 2024-12-04 Mengsi Gao

Network controllability is a powerful tool to study causal relationships in complex systems and identify the driver nodes for steering the network dynamics into desired states. However, due to ill-posed conditions, results become unreliable…

This paper exploits bisimulation relations, generated by extracting the concept of morphisms between algebraic structures, to analyze set stabilization of Boolean control networks with lower complexity. First, for two kinds of bisimulation…

最优化与控制 · 数学 2024-12-25 Tiantian Mu , Jun-e Feng , Biao Wang

In recent years, data-driven approaches have become increasingly pervasive across all areas of control engineering. However, the applications of data-based techniques to Boolean control networks (BCNs) are still very limited. In this paper…

系统与控制 · 电气工程与系统科学 2026-02-16 Giorgia Disarò , Maria Elena Valcher

Our daily social and political life is more and more impacted by social networks. The functioning of our living bodies is deeply dependent on biological regulation networks such as neural, genetic, and protein networks. And the physical…

离散数学 · 计算机科学 2022-04-25 Jacques Demongeot , Tarek Melliti , Mathilde Noual , Damien Regnault , Sylvain Sené

We consider a general class of stochastic networks and ask which network nodes need to be controlled, and how, to stabilize and switch between desired metastable (target) states in terms of the first and second statistical moments of the…

适应与自组织系统 · 物理学 2016-07-20 Dmytro Bielievtsov , Josef Ladenbauer , Klaus Obermayer

This paper addresses a structural design problem in control systems, and explicitly takes into consideration the possible application to large-scale systems. More precisely, we aim to determine and characterize the minimum number of…

最优化与控制 · 数学 2016-06-13 Sergio Pequito , George J. Pappas