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Multimodal large language models (MLLMs) have shown remarkable potential in various domains, yet their application in the medical field is hindered by several challenges. General-purpose MLLMs often lack the specialized knowledge required…

人工智能 · 计算机科学 2025-09-29 Guanghao Zhu , Zhitian Hou , Zeyu Liu , Zhijie Sang , Congkai Xie , Hongxia Yang

According to the 2021 World Health Organization (WHO) Classification scheme for gliomas, glioma segmentation is a very important basis for diagnosis and genotype prediction. In general, 3D multimodal brain MRI is an effective diagnostic…

图像与视频处理 · 电气工程与系统科学 2025-06-23 Xiaoyu Shi , Shurong Chai , Yinhao Li , Jingliang Cheng , Jie Bai , Guohua Zhao , Yen-Wei Chen

Brain image registration transforms a pair of images into one system with the matched imaging contents, which is of essential importance for brain image analysis. This paper presents a novel framework for unsupervised 3D brain image…

计算机视觉与模式识别 · 计算机科学 2019-07-04 Lihao Liu , Xiaowei Hu , Lei Zhu , Pheng-Ann Heng

Accurate registration of medical images is vital for doctor's diagnosis and quantitative analysis. In this paper, we propose a new deformable medical image registration method based on average geometric transformations and VoxelMorph CNN…

计算机视觉与模式识别 · 计算机科学 2019-07-24 Yongpei Zhu , Zicong Zhou , Guojun Liao , Kehong Yuan

Diffusion-weighted magnetic resonance imaging (DW-MRI) is a non-invasive way of imaging white matter tracts in the human brain. DW-MRIs are usually acquired using echo-planar imaging (EPI) with high gradient fields, which could introduce…

图像与视频处理 · 电气工程与系统科学 2023-04-04 Zhangxing Bian , Muhan Shao , Aaron Carass , Jerry L. Prince

Schizophrenia is a chronic neuropsychiatric disorder that causes distinct structural alterations within the brain. We hypothesize that deep learning applied to a structural neuroimaging dataset could detect disease-related alteration and…

图像与视频处理 · 电气工程与系统科学 2022-07-08 Junhao Zhang , Vishwanatha M. Rao , Ye Tian , Yanting Yang , Nicolas Acosta , Zihan Wan , Pin-Yu Lee , Chloe Zhang , Lawrence S. Kegeles , Scott A. Small , Jia Guo

Healthcare data now span EHRs, medical imaging, genomics, and wearable sensors, but most diagnostic models still process these modalities in isolation. This limits their ability to capture early, cross-modal disease signatures. This paper…

机器学习 · 计算机科学 2025-12-18 Md Talha Mohsin , Ismail Abdulrashid

Understanding brain disorders is crucial for accurate clinical diagnosis and treatment. Recent advances in Multimodal Large Language Models (MLLMs) offer a promising approach to interpreting medical images with the support of text…

图像与视频处理 · 电气工程与系统科学 2025-06-03 Jing Zhang , Xiaowei Yu , Yanjun Lyu , Lu Zhang , Tong Chen , Chao Cao , Yan Zhuang , Minheng Chen , Tianming Liu , Dajiang Zhu

We adapt structural complexity analysis to three-dimensional signals, with an emphasis on brain magnetic resonance imaging (MRI). This framework captures the multiscale organization of volumetric data by coarse-graining the signal at…

计算机视觉与模式识别 · 计算机科学 2026-01-27 Anzhe Cheng , Italo Ivo Lima Dias Pinto , Paul Bogdan

Accurate and reproducible brain morphometry from structural MRI is critical for monitoring neuroanatomical changes across time and across imaging domains. Although deep learning has accelerated segmentation workflows, scanner-induced…

计算机视觉与模式识别 · 计算机科学 2025-04-23 Ekaterina Kondrateva , Sandzhi Barg , Mikhail Vasiliev

Recent advances in multimodal large language models (LLMs) have enabled unified reasoning across images, audio, and video, but extending such capability to brain imaging remains largely unexplored. Bridging this gap is essential to link…

计算与语言 · 计算机科学 2026-05-15 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Chengxuan Qian , Tianyang Wang , Vince D. Calhoun

MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…

机器学习 · 计算机科学 2022-05-18 Haoteng Tang , Xiyao Fu , Lei Guo , Yalin Wang , Scott Mackin , Olusola Ajilore , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

计算机视觉与模式识别 · 计算机科学 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

Conventional medical image registration approaches directly optimize over the parameters of a transformation model. These approaches have been highly successful and are used generically for registrations of different anatomical regions.…

计算机视觉与模式识别 · 计算机科学 2024-03-12 Lin Tian , Hastings Greer , Roland Kwitt , Francois-Xavier Vialard , Raul San Jose Estepar , Sylvain Bouix , Richard Rushmore , Marc Niethammer

Diffeomorphic image registration is crucial for various medical imaging applications because it can preserve the topology of the transformation. This study introduces DCCNN-LSTM-Reg, a learning framework that evolves dynamically and learns…

图像与视频处理 · 电气工程与系统科学 2024-11-06 Jinqiu Deng , Ke Chen , Mingke Li , Daoping Zhang , Chong Chen , Alejandro F. Frangi , Jianping Zhang

The work proposes a novel deep-learning framework for the synthesis of three-dimensional MRI volumes from corresponding 3D ultrasound images of the brain, leveraging a modified iteration of the Pix2Pix Generative Adversarial Network (GAN)…

图像与视频处理 · 电气工程与系统科学 2024-07-19 Shubham Singh , Mrunal Bewoor , Ammar Ranapurwala , Satyam Rai , Sheetal Patil

In this study, we aim to initiate the development of Radiology Foundation Model, termed as RadFM. We consider the construction of foundational models from three perspectives, namely, dataset construction, model design, and thorough…

计算机视觉与模式识别 · 计算机科学 2023-11-17 Chaoyi Wu , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

Biomedical data is inherently multimodal, consisting of electronic health records, medical imaging, digital pathology, genome sequencing, wearable sensors, and more. The application of artificial intelligence tools to these multifaceted…

机器学习 · 计算机科学 2024-08-26 Shentong Mo , Paul Pu Liang

Deformable image registration (DIR) is a crucial and challenging technique for aligning anatomical structures in medical images and is widely applied in diverse clinical applications. However, existing approaches often struggle to capture…

图像与视频处理 · 电气工程与系统科学 2025-08-26 Shayan Kebriti , Shahabedin Nabavi , Ali Gooya

Functional magnetic resonance imaging (fMRI) is a powerful tool for probing brain function, yet reliable clinical diagnosis is hampered by low signal-to-noise ratios, inter-subject variability, and the limited frequency awareness of…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Junhao Jia , Yifei Sun , Yunyou Liu , Cheng Yang , Changmiao Wang , Feiwei Qin , Yong Peng , Wenwen Min
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