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A patient's digital twin is a computational model that describes the evolution of their health over time. Digital twins have the potential to revolutionize medicine by enabling individual-level computer simulations of human health, which…

Human digital twins (HDTs) are dynamic, data-driven virtual representations of individuals, continuously updated with multimodal data to simulate, monitor, and predict health trajectories. By integrating clinical, physiological, behavioral,…

人机交互 · 计算机科学 2025-08-19 Rong Pan , Hongyue Sun , Xiaoyu Chen , Giulia Pedrielli , Jiapeng Huang

Digital Twin (DT) has gained great interest as an innovative technology in Industry 4.0 that enables advanced modeling, simulation, and optimization of service and manufacturing systems. This article provides an extensive review of the…

综合数学 · 数学 2026-01-26 Sarow Saeedi

Quantifying the uncertainty in predictive models is critical for establishing trust and enabling risk-informed decision making for personalized medicine. In contrast to one-size-fits-all approaches that seek to mitigate risk at the…

计算工程、金融与科学 · 计算机科学 2025-05-15 Graham Pash , Umberto Villa , David A. Hormuth , Thomas E. Yankeelov , Karen Willcox

Clinical trials are indispensable for medical research and the development of new treatments. However, clinical trials often involve thousands of participants and can span several years to complete, with a high probability of failure during…

机器学习 · 计算机科学 2024-07-02 Yue Wang , Tianfan Fu , Yinlong Xu , Zihan Ma , Hongxia Xu , Yingzhou Lu , Bang Du , Honghao Gao , Jian Wu

Central to the digital transformation of the process industry are Digital Twins (DTs), virtual replicas of physical manufacturing systems that combine sensor data with sophisticated data-based or physics-based models, or a combination…

机器学习 · 计算机科学 2024-07-03 Michael Mayr , Georgios C. Chasparis , Josef Küng

The growing complexity of healthcare systems requires advanced computational models for real-time monitoring, secure data exchange, and intelligent decision-making. Digital Twins (DTs) provide virtual representations of physical healthcare…

新兴技术 · 计算机科学 2026-02-18 Asma Taheri Monfared , Andrea Bombarda , Angelo Gargantini , Majid Haghparast

Digital twins (DTs) are redefining healthcare by paving the way for more personalized, proactive, and intelligent medical interventions. As the shift toward personalized care intensifies, there is a growing need for an individual's virtual…

人机交互 · 计算机科学 2025-03-18 Melvin Mokhtari

Emerging from NASA's spacecraft simulations in the 1960s, digital twin technology has advanced through industrial adoption to spark a healthcare transformation. A digital twin is a dynamic, data-driven virtual counterpart of a physical…

人工智能 · 计算机科学 2025-11-27 Yunqi Zhang , Kuangyu Shi , Biao Li

Power systems are inherently multi-timescale systems, with different physical phenomena and decision-making processes spanning multiple timescales, time horizons, and geographic scopes. I envision power systems digital twins (DTs) as…

系统与控制 · 电气工程与系统科学 2026-05-08 Pedro P. Vergara

Digital Twins (DTs) are becoming increasingly vital for future industrial applications, enhancing monitoring, control, and optimization of physical assets. This enhancement is made possible by integrating various Digital Models (DMs) within…

Chronic diseases constitute the principal burden of morbidity, mortality, and healthcare costs worldwide, yet current health systems remain fragmented and predominantly reactive. Patient Medical Digital Twins (PMDTs) offer a paradigm shift:…

软件工程 · 计算机科学 2026-02-13 Micheal P. Papazoglou , Bernd J. Krämer , Mira Raheem , Amal Elgammal

This article presents the general framework of theranostic digital twins (TDTs) in computational nuclear medicine, designed to support clinical decision-making and improve cancer patient prognosis through personalized radiopharmaceutical…

其他定量生物学 · 定量生物学 2025-11-07 Marc Ryhiner , Yangmeihui Song , Babak Saboury , Gerhard Glatting , Arman Rahmim , Kuangyu Shi

Recent technological advances have expanded the availability of high-throughput biological datasets, enabling the reliable design of digital twins of biomedical systems or patients. Such computational tools represent key reaction networks…

定量方法 · 定量生物学 2025-09-03 Clémence Métayer , Annabelle Ballesta , Julien Martinelli

One of the challenges of predictive maintenance is making decisions based on data in an agile and assertive way. Connected sensors and operational data favor intelligent processing techniques to enrich information and enable…

软件工程 · 计算机科学 2025-11-12 Izaque Esteves , Regina Braga , José Maria David , Victor Stroele

With the accelerating availability of multimodal surgical data and real-time computation, Surgical Digital Twins (SDTs) have emerged as virtual counterparts that mirror, predict, and inform decisions across pre-, intra-, and postoperative…

Digital Twins (DTs) are set to become a key enabling technology in future wireless networks, with their use in network management increasing significantly. We developed a DT framework that leverages the heterogeneity of network access…

网络与互联网体系结构 · 计算机科学 2024-08-07 Roberto Morabito , Bivek Pandey , Paulius Daubaris , Yasith R Wanigarathna , Sasu Tarkoma

Artificial Intelligence (AI) and Large Language Models (LLMs) hold significant promise in revolutionizing healthcare, especially in clinical applications. Simultaneously, Digital Twin technology, which models and simulates complex systems,…

人工智能 · 计算机科学 2024-09-27 Himanshu Pandey , Akhil Amod , Shivang , Kshitij Jaggi , Ruchi Garg , Abheet Jain , Vinayak Tantia

Medical imaging has played a pivotal role in advancing and refining digital twin technology, allowing for the development of highly personalized virtual models that represent human anatomy and physiological functions. A key component in…

医学物理 · 物理学 2024-11-14 Feng Zhao , Yizhou Wu , Mingzhe Hu , Chih-Wei Chang , Ruirui Liu , Richard Qiu , Xiaofeng Yang

Digital twin technology has is anticipated to transform healthcare, enabling personalized medicines and support, earlier diagnoses, simulated treatment outcomes, and optimized surgical plans. Digital twins are readily gaining traction in…

机器学习 · 计算机科学 2023-07-12 Logan Nye
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