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相关论文: Improving Causal Inference with Measurement Errors…

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Estimating causal effects from observational data is inherently challenging due to the lack of observable counterfactual outcomes and even the presence of unmeasured confounding. Traditional methods often rely on restrictive, untestable…

统计方法学 · 统计学 2025-04-07 Li Chen , Xiaotong Shen , Wei Pan

This paper presents an approach to estimating the health effects of an environmental hazard. The approach is general in nature, but is applied here to the case of air pollution. It uses a computer model involving ambient pollution and…

应用统计 · 统计学 2007-11-01 Gavin Shaddick , Duncan Lee , James V. Zidek , Ruth Salway

Evaluating the causal health effects of multivariate, continuous exposures, such as air pollution mixtures, is a critical public health challenge. A primary obstacle is the frequent violation of the positivity assumption, which renders the…

统计方法学 · 统计学 2026-05-05 Zhuochao Huang , Kejin Dong , Tuo Lin , Joseph Antonelli

The Cox regression model is a popular model for analyzing the relationship between a covariate and a survival endpoint. The standard Cox model assumes a constant covariate effect across the entire covariate domain. However, in many…

应用统计 · 统计学 2019-09-02 Sarit Agami , David M. Zucker , Donna Spiegelman

Quantifying associations between short-term exposure to ambient air pollution and health outcomes is an important public health priority. Many studies have investigated the association considering delayed effects within the past few days.…

统计方法学 · 统计学 2025-05-22 Tianyi Pan , Hwashin Hyun Shin , Glen McGee , Alex Stringer

The proximal causal inference framework enables the identification and estimation of causal effects in the presence of unmeasured confounding by leveraging two disjoint sets of observed strong proxies: negative control treatments and…

统计方法学 · 统计学 2025-12-16 Antonio Olivas-Martinez , Peter B. Gilbert , Andrea Rotnitzky

Statistical models often require inputs that are not completely known. This can occur when inputs are measured with error, indirectly, or when they are predicted using another model. In environmental epidemiology, air pollution exposure is…

统计方法学 · 统计学 2025-12-23 Konstantin Larin , Daniel R. Kowal

Estimating average causal effect (ACE) is useful whenever we want to know the effect of an intervention on a given outcome. In the absence of a randomized experiment, many methods such as stratification and inverse propensity weighting have…

机器学习 · 计算机科学 2019-07-11 Rathin Desai , Amit Sharma

Confounding and exposure measurement error can introduce bias when drawing inference about the marginal effect of an exposure on an outcome of interest. While there are broad methodologies for addressing each source of bias individually,…

统计方法学 · 统计学 2025-01-29 Brian D. Richardson , Bryan S. Blette , Peter B. Gilbert , Michael G. Hudgens

A typical problem in air pollution epidemiology is exposure assessment for individuals for which health data are available. Due to the sparsity of monitoring sites and the limited temporal frequency with which measurements of air pollutants…

Environmental exposures are often defined using buffer zones around geocoded home addresses, but these static boundaries can miss dynamic daily activity patterns, leading to biased results. This paper presents a novel measurement error…

统计方法学 · 统计学 2024-10-15 Lin Ge , Ce Yang , David Zucker , Jiaxuan Li , Donna Spiegelman , Molin Wang

Exposure measurement error is a ubiquitous but often overlooked challenge in causal inference with observational data. Existing methods accounting for exposure measurement error largely rely on restrictive parametric assumptions, while…

统计方法学 · 统计学 2025-06-27 Keith Barnatchez , Rachel Nethery , Bryan E. Shepherd , Giovanni Parmigiani , Kevin P. Josey

Fine particulate matter and aerosol optical thickness are of interest to atmospheric scientists for understanding air quality and its various health/environmental impacts. The available data are extremely large, making uncertainty…

统计方法学 · 统计学 2025-03-05 Madelyn Clinch , Jonathan R. Bradley

Unmeasured confounding, unethical exposure, and ill-defined interventions pose significant challenges to evaluating policy-relevant mediation estimands in medicine and public health. In observational studies involving harmful exposures, the…

统计方法学 · 统计学 2026-05-12 Yang Bai , Yifan Cui , Baoluo Sun

In observational studies, potential unobserved confounding is a major barrier in isolating the average causal effect (ACE). In these scenarios, two main approaches are often used: confounder adjustment for causality (CAC) and instrumental…

统计方法学 · 统计学 2024-11-26 Roy S. Zawadzki , Daniel L. Gillen

An important issue is that the respiratory mortality may be a result of air pollution which can be measured by the following variables: temperature, relative humidity, carbon monoxide, sulfur dioxide, nitrogen dioxide, hydrocarbons, ozone…

应用统计 · 统计学 2019-07-11 Bahadır Yüzbaşı , Yasin Aşar , Şamil Şık , Ahmet Demiralp

In epidemiological studies of air pollution and public health, estimating the health impact of exposure to air pollution may be hindered by the unknown functional form of the exposure-outcome association and by unmeasured confounding…

统计方法学 · 统计学 2026-01-28 Carlo Zaccardi , Pasquale Valentini , Luigi Ippoliti , Alexandra M. Schmidt

Small area ecological studies are commonly used in epidemiology to assess the impact of area level risk factors on health outcomes when data are only available in an aggregated form. However the resulting estimates are often biased due to…

应用统计 · 统计学 2017-01-19 Yingbo Wang , Sylvia Richardson , Anna Hansell , Marta Blangiardo

Motivated by environmental policy questions, we address the challenges of estimation, change point detection, and uncertainty quantification of a causal exposure-response function (CERF). Under a potential outcome framework, the CERF…

统计方法学 · 统计学 2023-01-27 Boyu Ren , Xiao Wu , Danielle Braun , Natesh Pillai , Francesca Dominici

Environmental epidemiology has traditionally examined single exposure one at a time. Advances in exposure assessment and statistical methods now enable studies of multiple exposures and their combined health impacts. Bayesian Kernel Machine…

统计方法学 · 统计学 2026-02-02 Danlu Zhang , Stephanie M. Eick , Howard H. Chang