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相关论文: Improving Causal Inference with Measurement Errors…

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Public health researchers often estimate health effects of exposures (e.g., pollution, diet, lifestyle) that cannot be directly measured for study subjects. A common strategy in environmental epidemiology is to use a first-stage (exposure)…

统计方法学 · 统计学 2014-06-03 Adam A. Szpiro , Christopher J. Paciorek

Numerous studies have examined the associations between long-term exposure to fine particulate matter (PM2.5) and adverse health outcomes. Recently, many of these studies have begun to employ high-resolution predicted PM2.5 concentrations,…

统计方法学 · 统计学 2022-11-29 Kevin P. Josey , Priyanka deSouza , Xiao Wu , Danielle Braun , Rachel Nethery

One way to quantify exposure to air pollution and its constituents in epidemiologic studies is to use an individual's nearest monitor. This strategy results in potential inaccuracy in the actual personal exposure, introducing bias in…

The Clean Air Act mandates that the National Ambient Air Quality Standards (NAAQS) must be routinely assessed to protect populations based on the latest science. Therefore, researchers should continue to address whether exposure to levels…

统计方法学 · 统计学 2020-01-09 Georgia Papadogeorgou , Francesca Dominici

We propose a new approach for estimating causal effects when the exposure is measured with error and confounding adjustment is performed via a generalized propensity score (GPS). Using validation data, we propose a regression calibration…

Regression calibration as developed by Rosner, Spiegelman and Willet is used to correct the bias in effect estimates due to measurement error in continuous exposures. The method involves two models: a measurement error model (MEM) relating…

统计方法学 · 统计学 2026-02-24 Wenze Tang , Donna Spiegelman , Xiaomei Liao , Molin Wang

We develop a causal inference approach to estimate the number of adverse health events prevented by large-scale air quality regulations via changes in exposure to multiple pollutants. This approach is motivated by regulations that impact…

应用统计 · 统计学 2019-09-23 Rachel C. Nethery , Fabrizia Mealli , Jason D. Sacks , Francesca Dominici

Introduction: Methods now exist to detect residual confounding. One requires an "indicator" with two key properties: conditional independence of the outcome (given exposure and measured covariates) absent confounding and other model…

统计方法学 · 统计学 2015-10-26 W. Dana Flanders , Matthew J. Strickland , Mitchel Klein

Studies have shown that exposure to air pollution, even at low levels, significantly increases mortality. As regulatory actions are becoming prohibitively expensive, robust evidence to guide the development of targeted interventions to…

应用统计 · 统计学 2018-02-20 Kwonsang Lee , Dylan S. Small , Francesca Dominici

Several epidemiological studies have provided evidence that long-term exposure to fine particulate matter (PM2.5) increases mortality risk. Furthermore, some population characteristics (e.g., age, race, and socioeconomic status) might play…

统计方法学 · 统计学 2023-11-01 Dafne Zorzetto , Falco J. Bargagli-Stoffi , Antonio Canale , Francesca Dominici

Exposure to fine particulate matter ($PM_{2.5}$) poses significant health risks and accurately determining the shape of the relationship between $PM_{2.5}$ and health outcomes has crucial policy ramifications. While various statistical…

应用统计 · 统计学 2023-06-06 Michael Cork , Daniel Mork , Francesca Dominici

Estimating the health effects of multiple air pollutants is a crucial problem in public health, but one that is difficult due to unmeasured confounding bias. Motivated by this issue, we develop a framework for partial identification of…

统计方法学 · 统计学 2025-06-23 Suyeon Kang , Alexander Franks , Michelle Audirac , Danielle Braun , Joseph Antonelli

Analysis of observational studies increasingly confronts the challenge of determining which of a possibly high-dimensional set of available covariates are required to satisfy the assumption of ignorable treatment assignment for estimation…

统计方法学 · 统计学 2022-03-23 Chanmin Kim , Mauricio Tec , Corwin M Zigler

In this paper, we undertake a case study to estimate a causal exposure-response function (ERF) for long-term exposure to fine particulate matter (PM$_{2.5}$) and respiratory hospitalizations in socioeconomically disadvantaged children using…

统计方法学 · 统计学 2024-07-15 Jenny J. Lee , Xiao Wu , Francesca Dominici , Rachel C. Nethery

Ambient fine particulate matter less than 2.5 $\mu$m in aerodynamic diameter (PM$_{2.5}$) has been linked to various adverse health outcomes and has, therefore, gained interest in public health. However, the sparsity of air quality monitors…

应用统计 · 统计学 2018-02-12 Nancy Murray , Howard H. Chang , Heather Holmes , Yang Liu

In this paper, we identify the criteria for the selection of the minimal and most efficient covariate adjustment sets for the regression calibration method developed by Carroll, Rupert and Stefanski (CRS, 1992), used to correct bias due to…

统计方法学 · 统计学 2024-01-17 Wenze Tang , Donna Spiegelman , Yujie Wu , Molin Wang

Studies of the relationships between environmental exposures and adverse health outcomes often rely on a two-stage statistical modeling approach, where exposure is modeled/predicted in the first stage and used as input to a separately fit…

统计方法学 · 统计学 2022-04-01 Saskia Comess , Howard H. Chang , Joshua L. Warren

This study develops a Bayesian hierarchical model to explore the effects of air pollution on respiratory and cardiovascular mortality in Los Angeles County. The model takes into account various pollutants such as PM2.5, PM10, CO, SO2, NO2…

应用统计 · 统计学 2025-01-29 Yanfei Qu , David A. Stephens

The association between multidimensional exposure patterns and outcomes is commonly investigated by first applying cluster analysis algorithms to derive patterns and then estimating the associations. However, errors in the underlying…

统计方法学 · 统计学 2023-05-31 Timm Intemann , Iris Pigeot

We develop new methodology to improve our understanding of the causal effects of multivariate air pollution exposures on public health. Typically, exposure to air pollution for an individual is measured at their home geographic region,…

统计方法学 · 统计学 2025-11-18 Heejun Shin , Danielle Braun , Kezia Irene , Michelle Audirac , Joseph Antonelli
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