中文
相关论文

相关论文: Quantification of vaccine waning as a challenge ef…

200 篇论文

The crisis caused by the COVID-19 outbreak around the globe raised an increasing concern about the ongoing emergence of variants of SARS-CoV-2 that may evade the immune response provided by vaccines. New variants appear due to mutation, and…

种群与进化 · 定量生物学 2022-12-14 M. Ahumada , A. Ledesma-Araujo , Leonardo Gordillo , Juan F. Marín

We investigate the short-time dynamics of a delta-function potential barrier on an initially confined wave-packet. There are mainly two conclusions: A) At short times the probability density of the first particles that passed through the…

量子物理 · 物理学 2007-05-23 Er'el Granot , Avi Marchewka

Stratifying factors, like age and gender, can modify the effect of treatments and exposures on risk of a studied outcome. Several effect measures, including the relative risk, hazard ratio, odds ratio, and risk difference, can be used to…

统计方法学 · 统计学 2021-11-05 Jake Shannin , Babette A. Brumback

Explicit knowledge of total community-level immune seroprevalence is critical to developing policies to mitigate the social and clinical impact of SARS-CoV-2. Publicly available vaccination data are frequently cited as a proxy for…

应用统计 · 统计学 2022-02-21 Yajuan Si , Leonard Covello , Siquan Wang , Theodore Covello , Andrew Gelman

This study presents survey results of the public's willingness to get vaccinated against COVID-19 during an early phase of the pandemic and examines factors that could influence vaccine acceptance based on a between-subjects design. A…

计算机与社会 · 计算机科学 2021-06-24 Gabriel Lima , Meeyoung Cha , Chiyoung Cha , Hyeyoung Hwang

Covid-19 vaccination has posed crucial challenges to policymakers and health administrations worldwide. In addition to the pressure posed by the pandemic, government administration has to strive against vaccine hesitancy, which seems to be…

应用统计 · 统计学 2022-03-29 Giulio Grossi

Vaccination against COVID-19 with the recently approved mRNA vaccines BNT162b2 (BioNTech/Pfizer) and mRNA-1273 (Moderna) is currently underway in a large number of countries. However, high incidence rates and rapidly spreading SARS-CoV-2…

Opposition to vaccination has long been a non-negligible public health phenomenon resulted from people's varied perceptions toward vaccination (e.g., vaccine-phobia). This paper investigates the voluntary vaccination behavior of a…

物理与社会 · 物理学 2019-09-04 Liqun Lu , Yanfeng Ouyang

Refined vaccine regimens containing variant-matched inserts are often authorized based on historical phase 3 efficacy trials together with immunobridging studies. Phase 3 trials are essential for establishing immune biomarkers that reliably…

统计方法学 · 统计学 2026-04-16 Pan Zhao , Peter B. Gilbert , Oliver Dukes , Bo Zhang

In the era of fast-paced precision medicine, observational studies play a major role in properly evaluating new treatments in clinical practice. Yet, unobserved confounding can significantly compromise causal conclusions drawn from…

机器学习 · 统计学 2026-03-20 Piersilvio De Bartolomeis , Javier Abad , Konstantin Donhauser , Fanny Yang

We consider a vaccination game that results with the introduction of premature and possibly scarce vaccines introduced in a desperate bid to combat the otherwise ravaging deadly pandemic. The response of unsure agents amid many…

动力系统 · 数学 2021-09-14 Vartika Singh , Khushboo Agarwal , Shubham , Veeraruna Kavitha

The effectiveness of vaccination highly depends on the choice of individuals to vaccinate, even if the same number of individuals are vaccinated. Vaccinating individuals with high centrality measures such as betweenness centrality (BC) and…

物理与社会 · 物理学 2021-12-30 Bukyoung Jhun

Analysis of variance (ANOVA) reveals some disadvantages, such as non-robustness against heteroscedastic or non-normal errors and using difference to overall mean as effect sizes only. As an alternative the multiple contrast test comparing…

统计方法学 · 统计学 2023-03-27 Ludwig A. Hothorn

The paper introduces a novel approach to global sensitivity analysis, grounded in the variance-covariance structure of random variables derived from random measures. The proposed methodology facilitates the application of…

统计方法学 · 统计学 2025-10-20 Caleb Deen Bastian , Herschel Rabitz , Grzegorz A Rempala

The COVID-19 pandemic has adversely affected US public health, resulting in over a hundred million cases and more than one million deaths. Vaccination is the key intervention against the COVID-19 pandemic. Multiple COVID-19 vaccines are now…

应用统计 · 统计学 2025-02-25 Asim K. Dey

Vaccine hesitancy is widespread, despite the government's information campaigns and the efforts of the World Health Organisation (WHO). Categorising the topics within vaccine-related narratives is crucial to understand the concerns…

计算与语言 · 计算机科学 2023-11-20 Yue Li , Carolina Scarton , Xingyi Song , Kalina Bontcheva

The approach of N. Gay for estimating the coverage of a multivalent vaccine from antibody prevalence data in certain age cohorts is improved by using computer aided elimination theory of variables. Hereby, Gay's usage of numerical…

概率论 · 数学 2007-05-23 D. Altmann , K. Altmann

While conducting probabilistic surveys is the gold standard for assessing vaccine coverage, implementing these surveys poses challenges for global health. There is a need for more convenient option that is more affordable and practical.…

应用统计 · 统计学 2026-03-30 Nathaniel Dyrkton , Shomoita Alam , Susan Shepherd , Ibrahim Sana , Kevin Phelan , Jay JH Park

The test-negative design (TND) is a resource-efficient observational study design that can assess vaccine effectiveness and exposure-proximal immune correlates of disease. The TND enrolls symptomatic individuals seeking diagnostic testing…

统计方法学 · 统计学 2026-05-22 Leah I. B. Andrews , Lars van der Laan , Peter B. Gilbert

In diseases with long-term immunity, vaccination is known to increase the average age at infection as a result of the decrease in the pathogen circulation. This implies that a vaccination campaign can have negative effects when a disease is…

种群与进化 · 定量生物学 2024-06-04 Fabio A. C. C. Chalub , Paulo Doutor , Paula Patrício , Maria do Céu Soares