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Clinical trials require strict adherence to medication protocols, yet dosing errors remain a persistent challenge affecting patient safety and trial integrity. We present an automated system for detecting dosing errors in unstructured…

人工智能 · 计算机科学 2026-04-23 Mohammad AL-Smadi

With COVID-19 now pervasive, identification of high-risk individuals is crucial. Using data from a major healthcare provider in Southwestern Pennsylvania, we develop survival models predicting severe COVID-19 progression. In this endeavor,…

Automated analysis of tissue sections allows a better understanding of disease biology and may reveal biomarkers that could guide prognosis or treatment selection. In digital pathology, less abundant cell types can be of biological…

图像与视频处理 · 电气工程与系统科学 2021-02-24 Yeman Brhane Hagos , Catherine SY Lecat , Dominic Patel , Lydia Lee , Thien-An Tran , Manuel Rodriguez- Justo , Kwee Yong , Yinyin Yuan

We present a pipeline in which unsupervised machine learning techniques are used to automatically identify subtypes of hospital patients admitted between 2017 and 2021 in a large UK teaching hospital. With the use of state-of-the-art…

In oncology phase I trials, model-assisted designs have been increasingly adopted because they enable adaptive yet operationally simple dose adjustment based on accumulating safety data, leading to a paradigm shift in dose-escalation…

统计方法学 · 统计学 2026-02-23 Kana Yamada , Hisato Sunami , Kentaro Takeda , Keisuke Hanada , Masahiro Kojima

Obtaining datasets labeled to facilitate model development is a challenge for most machine learning tasks. The difficulty is heightened for medical imaging, where data itself is limited in accessibility and labeling requires costly time and…

The development of medical vision-language foundation models has attracted significant attention in the field of medicine and healthcare due to their promising prospect in various clinical applications. While previous studies have commonly…

计算机视觉与模式识别 · 计算机科学 2024-02-27 Weijian Huang , Cheng Li , Hong-Yu Zhou , Jiarun Liu , Hao Yang , Yong Liang , Guangming Shi , Hairong Zheng , Shanshan Wang

The COVID-19 pandemic exposed critical limitations in diagnostic workflows: RT-PCR tests suffer from slow turnaround times and high false-negative rates, while CT-based screening offers faster complementary diagnosis but requires expert…

图像与视频处理 · 电气工程与系统科学 2026-03-18 Aadit Nilay , Bhavesh Thapar , Anant Agrawal , Mohammad Nayeem Teli

To maximize clinical benefit, clinicians routinely tailor treatment to the individual characteristics of each patient, where individualized treatment rules are needed and are of significant research interest to statisticians. In the…

统计方法学 · 统计学 2021-11-23 Trinetri Ghosh , Yanyuan Ma , Rui Song , Pingshou Zhong

The upheaval brought by the arrival of the COVID-19 pandemic has continued to bring fresh challenges over the past two years. During this COVID-19 pandemic, there has been a need for rapid identification of infected patients and specific…

图像与视频处理 · 电气工程与系统科学 2022-07-05 Ming Li , Yingying Fang , Zeyu Tang , Chibudom Onuorah , Jun Xia , Javier Del Ser , Simon Walsh , Guang Yang

False information has a significant negative influence on individuals as well as on the whole society. Especially in the current COVID-19 era, we witness an unprecedented growth of medical misinformation. To help tackle this problem with…

计算与语言 · 计算机科学 2022-04-27 Ivan Srba , Branislav Pecher , Matus Tomlein , Robert Moro , Elena Stefancova , Jakub Simko , Maria Bielikova

To contain the spread of the virus and stop the overcrowding of hospitalized patients, the coronavirus pandemic crippled healthcare facilities, mandating lockdowns and promoting remote work. As a result, telehealth has become increasingly…

Healthcare digitalization requires effective applications of human sensors, when various parameters of the human body are instantly monitored in everyday life due to the Internet of Things (IoT). In particular, machine learning (ML) sensors…

机器学习 · 计算机科学 2022-10-24 Andrei Velichko , Mehmet Tahir Huyut , Maksim Belyaev , Yuriy Izotov , Dmitry Korzun

This paper applies the recently axiomatized Optimum Information Principle (minimize the Kullback-Leibler information subject to all relevant information) to nonparametric density estimation, which provides a theoretical foundation as well…

统计理论 · 数学 2011-03-28 Alexis Akira Toda

Automatic disease image grading is a significant application of artificial intelligence for healthcare, enabling faster and more accurate patient assessments. However, domain shifts, which are exacerbated by data imbalance, introduce bias…

计算机视觉与模式识别 · 计算机科学 2025-05-02 Shuo Tong , Shangde Gao , Ke Liu , Zihang Huang , Hongxia Xu , Haochao Ying , Jian Wu

We introduce an approach which allows detecting causal relationships between variables for which the time evolution is available. Causality is assessed by a variational scheme based on the Information Imbalance of distance ranks, a…

统计方法学 · 统计学 2024-05-07 Vittorio Del Tatto , Gianfranco Fortunato , Domenica Bueti , Alessandro Laio

Despite the good results that have been achieved in unimodal segmentation, the inherent limitations of individual data increase the difficulty of achieving breakthroughs in performance. For that reason, multi-modal learning is increasingly…

图像与视频处理 · 电气工程与系统科学 2024-04-16 Yameng Wang , Yi Wan , Yongjun Zhang , Bin Zhang , Zhi Gao

We investigate the problem of estimating the causal effect of a treatment on individual subjects from observational data, this is a central problem in various application domains, including healthcare, social sciences, and online…

统计方法学 · 统计学 2019-01-30 Ahmed M. Alaa , Mihaela van der Schaar

Predicting time-to-event outcomes in large databases can be a challenging but important task. One example of this is in predicting the time to a clinical outcome for patients in intensive care units (ICUs), which helps to support critical…

统计计算 · 统计学 2019-08-06 Yingying Xu , Joon Lee , Joel A. Dubin

Background and Objective: Colorectal cancer is a high mortality cancer. Clinical data analysis plays a crucial role in predicting the survival of colorectal cancer patients, enabling clinicians to make informed treatment decisions. However,…

机器学习 · 计算机科学 2023-09-06 Sadegh Soleimani , Mahsa Bahrami , Mansour Vali
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