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As disease often alters the structural properties of soft tissue, noninvasive elastography techniques have emerged to quantitatively assess in vivo mechanical properties. Magnetic Resonance Elastography (MRE) based on dynamic deformations…
Raster-scan optoacoustic mesoscopy (RSOM) is a powerful, non-invasive optical imaging technique for functional, anatomical, and molecular skin and tissue analysis. However, both the manual and the automated analysis of such images are…
Abdominal aortic aneurysms (AAA) pose a significant clinical risk due to their potential for rupture, which is often asymptomatic but can be fatal. Although maximum diameter is commonly used for risk assessment, diameter alone is…
Existing shape estimation methods for deformable object manipulation suffer from the drawbacks of being off-line, model dependent, noise-sensitive or occlusion-sensitive, and thus are not appropriate for manipulation tasks requiring high…
The Multimodal Direct Inversion (MMDI) algorithm is widely used in Magnetic Resonance Elastography (MRE) to estimate tissue shear stiffness. However, MMDI relies on the Helmholtz equation, which assumes wave propagation in a uniform,…
Non-mass enhancing lesions (NME) constitute a diagnostic challenge in dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) of the breast. Computer Aided Diagnosis (CAD) systems provide physicians with advanced tools for analysis,…
Visualizing disease-induced scarring and fibrosis in the heart on cardiac magnetic resonance (CMR) imaging with contrast enhancement (LGE) is paramount in characterizing disease progression and quantifying pathophysiological substrates of…
Accurate, real-time monitoring of tissue ischemia is crucial to understand tissue health and guide surgery. Spectral imaging shows great potential for contactless and intraoperative monitoring of tissue oxygenation. Due to the difficulty of…
Incorporating human domain knowledge for breast tumor diagnosis is challenging, since shape, boundary, curvature, intensity, or other common medical priors vary significantly across patients and cannot be employed. This work proposes a new…
Analyzing large-scale data from simulations of turbulent flows is memory intensive, requiring significant resources. This major challenge highlights the need for data compression techniques. In this study, we apply a physics-informed Deep…
Tracking the pose of instruments is a central problem in image-guided surgery. For microscopic scenarios, optical coherence tomography (OCT) is increasingly used as an imaging modality. OCT is suitable for accurate pose estimation due to…
Current acoustic radiation force (ARF) based methods for quantifying tissue elasticity primarily rely on shear wave propagation. However, their spatial resolution is limited by the need for spatial averaging, and their accuracy is affected…
Robotic surgery promises enhanced precision and adaptability over traditional surgical methods. It also offers the possibility of automating surgical interventions, resulting in reduced stress on the surgeon, better surgical outcomes, and…
In robotic surgery, pattern cutting through a deformable material is a challenging research field. The cutting procedure requires a robot to concurrently manipulate a scissor and a gripper to cut through a predefined contour trajectory on…
To develop a deep-learning method for achieving fast high-resolution MR elastography from highly undersampled data without the need of high-quality training dataset. We first framed the deep neural network representation as a nonlinear…
Shear-wave elastography (SWE) measures shear-wave speed (SWS), which is related to the underlying shear modulus of soft tissue. SWE methods generally assume that soft tissue viscoelasticity is independent of mechanical loading, however,…
Purposes: This study aimed to develop a computed tomography (CT)-based multi-organ segmentation model for delineating organs-at-risk (OARs) in pediatric upper abdominal tumors and evaluate its robustness across multiple datasets. Materials…
Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep…
Optical coherence tomography (OCT) is a non-invasive imaging technique widely used for ophthalmology. It can be extended to OCT angiography (OCT-A), which reveals the retinal vasculature with improved contrast. Recent deep learning…
Soft optical tactile sensors enable robots to manipulate deformable objects by capturing important features such as high-resolution contact geometry and estimations of object compliance. This work presents a variable stiffness soft tactile…