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相关论文: From virtual patients to digital twins in immuno-o…

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EC funded STriTuVaD project aims to test, through a phase IIb clinical trial, two of the most advanced therapeutic vaccines against tuberculosis. In parallel, we have extended the Universal Immune System Simulator to include all relevant…

定量方法 · 定量生物学 2019-10-29 Marzio Pennisi , Miguel A. Juarez , Giulia Russo , Marco Viceconti , Francesco Pappalardo

The COVID19 pandemic has demonstrated a need for remote learning and virtual learning applications such as virtual reality (VR) and tablet-based solutions. Creating complex learning scenarios by developers is highly time-consuming and can…

人机交互 · 计算机科学 2022-07-22 Claire Palmer , Ben Roullier , Muhammad Aamir , Frank McQuade , Leonardo Stella , Ashiq Anjum

As the population grows, the need for a quality level of medical services grows correspondingly, so does the demand for information technology in medicine. The concept of "Smart Healthcare" offers many approaches aimed at solving the acute…

计算机与社会 · 计算机科学 2021-06-23 Ivan Volkov , Gleb Radchenko , Andrey Tchernykh

The idea of a systematic digital representation of the entire known human pathophysiology, which we could call the Virtual Human Twin, has been around for decades. To date, most research groups focused instead on developing highly…

医学物理 · 物理学 2023-08-15 Marco Viceconti , Maarten De Vos , Sabato Mellone , Liesbet Geris

This survey examines recent advances in generating digital twins from visual data. These digital twins - virtual 3D replicas of physical assets - can be applied to robotics, media content creation, design or construction workflows. We…

计算机视觉与模式识别 · 计算机科学 2026-02-18 Andrew Melnik , Benjamin Alt , Giang Nguyen , Artur Wilkowski , Maciej Stefańczyk , Qirui Wu , Sinan Harms , Helge Rhodin , Manolis Savva , Michael Beetz

A digital twin can be defined as an adaptive model of a complex physical system. Recent advances in computational pipelines, multiphysics solvers, artificial intelligence, big data cybernetics, data processing and management tools bring the…

信号处理 · 电气工程与系统科学 2019-10-07 Adil Rasheed , Omer San , Trond Kvamsdal

As a bridge from virtuality to reality, Digital Twin has increased in popularity since proposed. Ideas have been proposed theoretical and practical for digital twins. From theoretical perspective, digital twin is fusion of data mapping…

计算机与社会 · 计算机科学 2024-03-27 Lu Jingyu

The digital twin has emerged as a technology to predict the undesirables, and ensure desired performance of complex systems. Although digital twins have got attention in the manufacturing research spectrum, yet their industrial application…

系统与控制 · 电气工程与系统科学 2021-04-08 Ali Ahmad Malik

This article presents the general framework of theranostic digital twins (TDTs) in computational nuclear medicine, designed to support clinical decision-making and improve cancer patient prognosis through personalized radiopharmaceutical…

其他定量生物学 · 定量生物学 2025-11-07 Marc Ryhiner , Yangmeihui Song , Babak Saboury , Gerhard Glatting , Arman Rahmim , Kuangyu Shi

The vision of personalized medicine is to identify interventions that maintain or restore a person's health based on their individual biology. Medical digital twins, computational models that integrate a wide range of health-related data…

定量方法 · 定量生物学 2025-10-21 Luis L. Fonseca , Lucas Böttcher , Borna Mehrad , Reinhard C. Laubenbacher

We propose a digital twin approach to improve healthcare decision support systems with a combination of domain knowledge and data. Domain knowledge helps build decision thresholds that doctors can use to determine a risk or recommend a…

人工智能 · 计算机科学 2019-10-31 Dattaraj Jagdish Rao , Shraddha Mane

A digital twin is a virtual replica of a real-world physical phenomena that uses mathematical modeling to characterize and simulate its defining features. By constructing digital twins for disease processes, we can perform in-silico…

Human digital twins (HDTs) are dynamic, data-driven virtual representations of individuals, continuously updated with multimodal data to simulate, monitor, and predict health trajectories. By integrating clinical, physiological, behavioral,…

人机交互 · 计算机科学 2025-08-19 Rong Pan , Hongyue Sun , Xiaoyu Chen , Giulia Pedrielli , Jiapeng Huang

This review examines current and potential applications of DTs in healthcare, focusing on the integration of multi-omics data using multilayer network approaches in cancer research. We discuss methodologies, tools and platforms commonly…

分子网络 · 定量生物学 2024-10-11 Hugo Chenel , Malvina Marku , Tim James , Andrei Zinovyev , Vera Pancaldi

The goal of cancer immunotherapy is to boost a patient's immune response to a tumor. Yet, the design of an effective immunotherapy is complicated by various factors, including a potentially immunosuppressive tumor microenvironment,…

组织与器官 · 定量生物学 2017-06-29 Anna Konstorum , Anthony T. Vella , Adam J. Adler , Reinhard Laubenbacher

The concept of creating digital twins, connected digital models of physical systems, is gaining increasing attention for modeling and simulation of whole cities. The basis for building a digital twin of a city is the generation of a 3D city…

图形学 · 计算机科学 2022-10-12 Vasilis Naserentin , Anders Logg

Digital twins are virtual systems designed to predict how a real-world process will evolve in response to interventions. This modelling paradigm holds substantial promise in many applications, but rigorous procedures for assessing their…

统计方法学 · 统计学 2023-11-03 Rob Cornish , Muhammad Faaiz Taufiq , Arnaud Doucet , Chris Holmes

Digital twins (DTs) are redefining healthcare by paving the way for more personalized, proactive, and intelligent medical interventions. As the shift toward personalized care intensifies, there is a growing need for an individual's virtual…

人机交互 · 计算机科学 2025-03-18 Melvin Mokhtari

A cardiac digital twin is a virtual replica of a patient's heart for screening, diagnosis, prognosis, risk assessment, and treatment planning of cardiovascular diseases. This requires an anatomically accurate patient-specific 3D structural…

Future wireless services must be focused on improving the quality of life by enabling various applications, such as extended reality, brain-computer interaction, and healthcare. These applications have diverse performance requirements…

网络与互联网体系结构 · 计算机科学 2022-02-08 Latif U. Khan , Zhu Han , Walid Saad , Ekram Hossain , Mohsen Guizani , Choong Seon Hong