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Estimating causal effects from observational data is inherently challenging due to the lack of observable counterfactual outcomes and even the presence of unmeasured confounding. Traditional methods often rely on restrictive, untestable…

统计方法学 · 统计学 2025-04-07 Li Chen , Xiaotong Shen , Wei Pan

Treatment effect estimation, which refers to the estimation of causal effects and aims to measure the strength of the causal relationship, is of great importance in many fields but is a challenging problem in practice. As present,…

机器学习 · 计算机科学 2021-07-20 Zhenyu Guo , Shuai Zheng , Zhizhe Liu , Kun Yan , Zhenfeng Zhu

Mixed effects regression models are widely used by language researchers. However, these regressions are implemented with an algorithm which may not converge on a solution. While convergence issues in linear mixed effects models can often be…

应用统计 · 统计学 2018-09-10 Amelia Kimball , Kailen Shantz , Christopher Eager , Joseph Roy

A powerful tool for the analysis of nonrandomized observational studies has been the potential outcomes model. Utilization of this framework allows analysts to estimate average treatment effects. This article considers the situation in…

统计理论 · 数学 2019-05-31 Debashis Ghosh , Efrén Cruz-Cortés

Nested error regression models are useful tools for analysis of grouped data, especially in the case of small area estimation. This paper suggests a nested error regression model using uncertain random effects in which the random effect in…

统计方法学 · 统计学 2017-02-28 Shonosuke Sugasawa , Tatsuya Kubokawa

Assessment of replicability is critical to ensure the quality and rigor of scientific research. In this paper, we discuss inference and modeling principles for replicability assessment. Targeting distinct application scenarios, we propose…

统计方法学 · 统计学 2021-05-11 Yi Zhao , Xiaoquan Wen

Interim analyses are vital in clinical trials for early decision-making. While frequentist implications are well-established, the consequences of repeated Bayesian interim monitoring for efficacy, specifically regarding multiplicity, remain…

统计方法学 · 统计学 2025-12-30 Suyu Liu , Beibei Guo , Laura Thompson , Lei Nie , Ying Yuan

Best linear unbiased prediction is well known for its wide range of applications including small area estimation. While the theory is well established for mixed linear models and under normality of the error and mixing distributions, the…

统计理论 · 数学 2007-06-13 Soumendra N. Lahiri , Tapabrata Maiti , Myron Katzoff , Van Parsons

This article aims to study efficient/trace optimal designs for crossover trials with multiple responses recorded from each subject in the time periods. A multivariate fixed effects model is proposed with direct and carryover effects…

统计方法学 · 统计学 2024-06-04 Shubham Niphadkar , Siuli Mukhopadhyay

We consider design-based causal inference for spatial experiments in which treatments may have effects that bleed out and feed back in complex ways. Such spatial spillover effects violate the standard ``no interference'' assumption for…

统计方法学 · 统计学 2024-08-06 Ye Wang , Cyrus Samii , Haoge Chang , P. M. Aronow

Performing causal inference in observational studies requires we assume confounding variables are correctly adjusted for. G-computation methods are often used in these scenarios, with several recent proposals using Bayesian versions of…

统计方法学 · 统计学 2021-10-25 Daniel Daly-Grafstein , Paul Gustafson

Causal excursion effect (CEE) characterizes the effect of an intervention under policies that deviate from the experimental policy. It is widely used to study the effect of time-varying interventions that have the potential to be frequently…

统计方法学 · 统计学 2024-06-14 Zhaoxi Cheng , Lauren Bell , Tianchen Qian

We construct a semiparametric estimator in case-control studies where the gene and the environment are assumed to be independent. A discrete or continuous parametric distribution of the genes is assumed in the model. A discrete distribution…

统计理论 · 数学 2010-10-12 Yanyuan Ma

In this article, universally optimal multivariate crossover designs are studied. The multiple response crossover design is motivated by a $3 \times 3$ crossover setup, where the effect of $3$ doses of an oral drug are studied on gene…

统计方法学 · 统计学 2024-07-16 Shubham Niphadkar , Siuli Mukhopadhyay

An N-of-1 trial is a multi-period crossover trial performed in a single individual, with a primary goal to estimate treatment effect on the individual instead of population-level mean responses. As in a conventional crossover trial, it is…

应用统计 · 统计学 2021-12-30 Ziwei Liao , Min Qian , Ian M. Kronish , Ying Kuen Cheung

Cross-classified data frequently arise in scientific fields such as education, healthcare, and social sciences. A common modeling strategy is to introduce crossed random effects within a regression framework. However, this approach often…

统计方法学 · 统计学 2025-07-22 Shota Takeishi , Shonosuke Sugasawa

Estimating heterogeneous treatment effects with machine learning has attracted substantial attention in both academic research and industrial practice. However, the two communities often evaluate models under markedly different conditions.…

机器学习 · 计算机科学 2026-05-26 George Panagopoulos

In many medical and business applications, researchers are interested in estimating individualized treatment effects using data from a randomized experiment. For example in medical applications, doctors learn the treatment effects from…

统计方法学 · 统计学 2022-03-01 Kevin Wu Han , Han Wu

{\bf Abstract} Consider a Non-Parametric Empirical Bayes (NPEB) setup. We observe $Y_i, \sim f(y|\theta_i)$, $\theta_i \in \Theta$ independent, where $\theta_i \sim G$ are independent $i=1,...,n$. The mixing distribution $G$ is unknown $G…

统计理论 · 数学 2024-05-10 Eitan Greenshtein

Randomized experiments are an excellent tool for estimating internally valid causal effects with the sample at hand, but their external validity is frequently debated. While classical results on the estimation of Population Average…

统计方法学 · 统计学 2023-01-13 Apoorva Lal , Wenjing Zheng , Simon Ejdemyr