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Segmentation and quantification of white matter hyperintensities (WMHs) are of great importance in studying and understanding various neurological and geriatric disorders. Although automatic methods have been proposed for WMH segmentation…

计算机视觉与模式识别 · 计算机科学 2018-03-20 Dakai Jin , Ziyue Xu , Adam P. Harrison , Daniel J. Mollura

White matter hyperintensities (WMH) are radiological markers of small vessel disease and neurodegeneration, whose accurate segmentation and spatial localization are crucial for diagnosis and monitoring. While multimodal MRI offers…

图像与视频处理 · 电气工程与系统科学 2025-06-30 Julia Machnio , Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

Automated segmentation of white matter hyperintensities (WMHs) is an essential step in neuroimaging analysis of Magnetic Resonance Imaging (MRI). Fluid Attenuated Inversion Recovery (FLAIR-weighted) is an MRI contrast that is particularly…

图像与视频处理 · 电气工程与系统科学 2023-05-15 Martin Soria Røvang , Per Selnes , Bradley John MacIntosh , Inge Rasmus Groote , Lene Paalhaugen , Sudre Carole , Tormod Fladby , Atle Bjørnerud

White matter hyperintensities (WMH) are key imaging markers in cognitive aging, Alzheimer's disease (AD), and related dementias. Although automated methods for WMH segmentation have advanced, most provide only global lesion load and…

计算机视觉与模式识别 · 计算机科学 2025-11-19 Julia Machnio , Mads Nielsen , Mostafa Mehdipour Ghazi

Segmentation has been a major task in neuroimaging. A large number of automated methods have been developed for segmenting healthy and diseased brain tissues. In recent years, deep learning techniques have attracted a lot of attention as a…

图像与视频处理 · 电气工程与系统科学 2019-07-05 Jimit Doshi , Guray Erus , Mohamad Habes , Christos Davatzikos

White Matter Hyperintensities (WMH) are areas of the brain that have higher intensity than other normal brain regions on Magnetic Resonance Imaging (MRI) scans. WMH is often associated with small vessel disease in the brain, making early…

图像与视频处理 · 电气工程与系统科学 2023-05-09 Muhammad Noor Dwi Eldianto , Muhammad Febrian Rachmadi , Wisnu Jatmiko

Ultra-high field 7-tesla (7T) MRI improves visualization of multiple sclerosis (MS) white matter lesions (WML) but differs sufficiently in contrast and artifacts from 1.5-3T imaging - suggesting that widely used automated segmentation tools…

计算机视觉与模式识别 · 计算机科学 2026-04-02 Michael Maynord , Minghui Liu , Cornelia Fermüller , Seongjin Choi , Yuxin Zeng , Shishir Dahal , Daniel M. Harrison

White matter hyperintensities (WMH) are commonly found in the brains of healthy elderly individuals and have been associated with various neurological and geriatric disorders. In this paper, we present a study using deep fully convolutional…

计算机视觉与模式识别 · 计算机科学 2018-09-20 Hongwei Li , Gongfa Jiang , Jianguo Zhang , Ruixuan Wang , Zhaolei Wang , Wei-Shi Zheng , Bjoern Menze

White Matter Hyperintensity (WMH) is an imaging feature related to various diseases such as dementia and stroke. Accurately segmenting WMH using computer technology is crucial for early disease diagnosis. However, this task remains…

图像与视频处理 · 电气工程与系统科学 2025-07-08 Changlu Guo

White matter hyperintensity (WMH) is commonly found in elder individuals and appears to be associated with brain diseases. U-net is a convolutional network that has been widely used for biomedical image segmentation. Recently, U-net has…

计算机视觉与模式识别 · 计算机科学 2018-07-30 Yue Zhang , Wanli Chen , Yifan Chen , Xiaoying Tang

Ultrahigh-field (UHF) magnetic resonance imaging (MRI), i.e., 7T MRI, provides superior anatomical details of internal brain structures owing to its enhanced signal-to-noise ratio and susceptibility-induced contrast. However, the widespread…

计算机视觉与模式识别 · 计算机科学 2024-02-14 Kwanseok Oh , Jieun Lee , Da-Woon Heo , Dinggang Shen , Heung-Il Suk

The accurate assessment of White matter hyperintensities (WMH) burden is of crucial importance for epidemiological studies to determine association between WMHs, cognitive and clinical data. The manual delineation of WMHs is tedious, costly…

组织与器官 · 定量生物学 2018-01-03 R. Guerrero , C. Qin , O. Oktay , C. Bowles , L. Chen , R. Joules , R. Wolz , M. C. Valdes-Hernandez , D. A. Dickie , J. Wardlaw , D. Rueckert

Convolutional neural networks (CNNs) achieved the state-of-the-art performance in medical image segmentation due to their ability to extract highly complex feature representations. However, it is argued in recent studies that traditional…

计算机视觉与模式识别 · 计算机科学 2025-03-31 Zhendi Gong , Andrew P. French , Guoping Qiu , Xin Chen

Brain atrophy and white matter hyperintensity (WMH) are critical neuroimaging features for ascertaining brain injury in cerebrovascular disease and multiple sclerosis. Automated segmentation and quantification is desirable but existing…

White Matter Hyperintensities (WMH) are the most common manifestation of cerebral small vessel disease (cSVD) on the brain MRI. Accurate WMH segmentation algorithms are important to determine cSVD burden and its clinical consequences. Most…

图像与视频处理 · 电气工程与系统科学 2020-12-23 Zicong Zhang , Kimerly Powell , Changchang Yin , Shilei Cao , Dani Gonzalez , Yousef Hannawi , Ping Zhang

Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

图像与视频处理 · 电气工程与系统科学 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

Medical image segmentation is a critical task that plays a vital role in diagnosis, treatment planning, and disease monitoring. Accurate segmentation of anatomical structures and abnormalities from medical images can aid in the early…

计算机视觉与模式识别 · 计算机科学 2023-09-14 Reza Azad , Amirhossein Kazerouni , Alaa Sulaiman , Afshin Bozorgpour , Ehsan Khodapanah Aghdam , Abin Jose , Dorit Merhof

The relationship between cognition and white matter hyperintensities (WMH) volumes often depends on the accuracy of the lesion segmentation algorithm used. As such, accurate detection and quantification of WMH is of great interest. Here, we…

图像与视频处理 · 电气工程与系统科学 2020-12-25 Lavanya Umapathy , Gloria Guzman Perez-Carillo , Blair Winegar , Srinivasan Vedantham , Maria Altbach , Ali Bilgin

White matter hyperintensities (WMH) and ischaemic stroke lesions (ISL) are imaging features associated with cerebral small vessel disease (SVD) that are visible on brain magnetic resonance imaging (MRI) scans. The development and validation…

计算机视觉与模式识别 · 计算机科学 2026-01-29 Jesse Phitidis , Alison Q. Smithard , William N. Whiteley , Joanna M. Wardlaw , Miguel O. Bernabeu , Maria Valdés Hernández
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