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Populations of heterogeneous cells play an important role in many biological systems. In this paper we consider systems where each cell can be modelled by an ordinary differential equation. To account for heterogeneity, parameter values are…

定量方法 · 定量生物学 2009-09-27 Steffen Waldherr , Jan Hasenauer , Frank Allgöwer

We consider the problem of estimating the mixing density $f$ from $n$ i.i.d. observations distributed according to a mixture density with unknown mixing distribution. In contrast with finite mixtures models, here the distribution of the…

统计理论 · 数学 2015-05-26 Tabea Rebafka , François Roueff

Experimental mechanisms that yield the growth of homochiral copolymers over their heterochiral counterparts have been advocated by Lahav and co-workers. These chiral amplification mechanisms proceed through racemic {\beta}-sheet-controlled…

定量方法 · 定量生物学 2012-12-19 Celia Blanco , David Hochberg

We derive an integration by parts formula for functionals of determinantal processes on compact sets, completing the arguments of [4]. This is used to show the existence of a configuration-valued diffusion process which is non-colliding and…

We consider the relation between the microscopic and effective descriptions of the unfolding experiment on a model polypeptide. We evaluate the probability distribution function of the performed work by Monte Carlo simulations and compare…

统计力学 · 物理学 2015-05-13 A. Imparato , L. Peliti

An incremental evolution equation, i.e. a Master equation in statistical mechanics, is introduced for force distributions in polydisperse frictional particle packings. As basic ingredients of the Master equation, the conditional probability…

软凝聚态物质 · 物理学 2015-05-29 Kuniyasu Saitoh , Vanessa Magnanimo , Stefan Luding

The Flory-Huggins theory is a well-established lattice model that is commonly used to study the mixing of distinct chemical species. It can successfully predict phase separation phenomena in blends of incompatible materials. However, it is…

材料科学 · 物理学 2025-12-19 Maxime Siber , Olivier J. J. Ronsin , Jens Harting

We estimate the probability regarding polymerization of a macromolecule which is made of distinct monomers. The lattice model of the random walk has been used to mimic the conformations of an ideal chain in two and three dimensions. It has…

软凝聚态物质 · 物理学 2020-09-21 Pramod Kumar Mishra

The Flory Huggins equation of state for monodisperse polymers can be turned into a density functional by adding a square gradient term, with a coefficient fixed by appeal to RPA (random phase approximation). We present instead a model…

软凝聚态物质 · 物理学 2009-11-07 I. Pagonabarraga , M. E. Cates

We introduce a new nonlinear model for classification, in which we model the joint distribution of response variable, y, and covariates, x, non-parametrically using Dirichlet process mixtures. We keep the relationship between y and x linear…

统计理论 · 数学 2007-05-23 Babak Shahbaba , Radford M. Neal

Most statistical software packages implement numerical strategies for computation of maximum likelihood estimates in random effects models. Little is known, however, about the algebraic complexity of this problem. For the one-way layout…

统计理论 · 数学 2013-05-07 Elizabeth Gross , Mathias Drton , Sonja Petrović

Obtaining a rigorous and reliable method for linking computer simulations of polymer blends and composites at different length scales of interest is a highly desirable goal in soft matter physics. In this paper a multiscale modeling…

软凝聚态物质 · 物理学 2015-05-19 J. McCarty , M. G. Guenza

We introduce a novel two-step approach for estimating a probability density function (pdf) given its samples, with the second and important step coming from a geometric formulation. The procedure involves obtaining an initial estimate of…

统计方法学 · 统计学 2017-12-14 Sutanoy Dasgupta , Debdeep Pati , Anuj Srivastava

Multidimensional population balance models (PBMs) describe chemical and biological processes having a distribution over two or more intrinsic properties (such as size and age, or two independent spatial variables). The incorporation of…

计算工程、金融与科学 · 计算机科学 2025-04-29 Pavan Inguva , Richard D. Braatz

Estimation of the number of components (or order) of a finite mixture model is a long standing and challenging problem in statistics. We propose the Group-Sort-Fuse (GSF) procedure -- a new penalized likelihood approach for simultaneous…

统计方法学 · 统计学 2021-08-06 Tudor Manole , Abbas Khalili

We propose a novel method for estimating nonseparable selection models. We show that, for a given selection function, the potential outcome distributions are nonparametrically identified from the selected outcome distributions and can be…

计量经济学 · 经济学 2026-05-05 Fan Wu , Yi Xin

In this paper homogenization of a mathematical model for biomechanics of a plant tissue with randomly distributed cells is considered. Mechanical properties of a plant tissue are modelled by a strongly coupled system of…

偏微分方程分析 · 数学 2020-10-28 Andrey Piatnitski , Mariya Ptashnyk

A model-based approach is developed for clustering categorical data with no natural ordering. The proposed method exploits the Hamming distance to define a family of probability mass functions to model the data. The elements of this family…

统计方法学 · 统计学 2024-07-02 Raffaele Argiento , Edoardo Filippi-Mazzola , Lucia Paci

Transient size segregation of a bi-disperse granular mixture flowing over a periodic chute is studied using the Discrete Element Method and continuum simulations. A recently developed particle force-based size segregation model is used to…

软凝聚态物质 · 物理学 2025-07-08 Soniya Kumawat , Vishnu Kumar Sahu , Anurag Tripathi

We present a new and general Monte Carlo iteration method for generalized ensembles. It consists of two elements: (1) a simple algorithm to distinguish between distributions arising from respectively equilibrium- and non-equilibrium…

凝聚态物理 · 物理学 2007-05-23 J. Borg