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Inaccuracies in existing or generated clinical text may lead to serious adverse consequences, especially if it is a misdiagnosis or incorrect treatment suggestion. With Large Language Models (LLMs) increasingly being used across diverse…

Social telehealth has revolutionized healthcare by enabling patients to share symptoms and receive medical consultations remotely. Users frequently post symptoms on social media and online health platforms, generating a vast repository of…

计算与语言 · 计算机科学 2025-02-04 Malak Mohamed , Rokaia Emad , Ali Hamdi

Large language models (LLMs) excel at text generation, but their ability to handle clinical classification tasks involving structured data, such as time series, remains underexplored. In this work, we adapt instruction-tuned LLMs using…

计算与语言 · 计算机科学 2025-09-18 Iyadh Ben Cheikh Larbi , Ajay Madhavan Ravichandran , Aljoscha Burchardt , Roland Roller

The massive scale and growth of textual biomedical data have made its indexing and classification increasingly important. However, existing research on this topic mainly utilized convolutional and recurrent neural networks, which generally…

计算与语言 · 计算机科学 2022-03-08 Bruce Nguyen , Shaoxiong Ji

Pathological diagnosis is vital for determining disease characteristics, guiding treatment, and assessing prognosis, relying heavily on detailed, multi-scale analysis of high-resolution whole slide images (WSI). However, existing large…

计算机视觉与模式识别 · 计算机科学 2025-05-19 Shengxuming Zhang , Weihan Li , Tianhong Gao , Jiacong Hu , Haoming Luo , Xiuming Zhang , Jing Zhang , Mingli Song , Zunlei Feng

Large language models (LLMs) are powerful tools capable of handling diverse tasks. Comparing and selecting appropriate LLMs for specific tasks requires systematic evaluation methods, as models exhibit varying capabilities across different…

计算与语言 · 计算机科学 2025-06-04 Anna Sokol , Elizabeth Daly , Michael Hind , David Piorkowski , Xiangliang Zhang , Nuno Moniz , Nitesh Chawla

Medical report generation demands automatic creation of coherent and precise descriptions for medical images. However, the scarcity of labelled medical image-report pairs poses formidable challenges in developing large-scale neural networks…

计算机视觉与模式识别 · 计算机科学 2023-12-08 Shibin Wu , Bang Yang , Zhiyu Ye , Haoqian Wang , Hairong Zheng , Tong Zhang

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

计算与语言 · 计算机科学 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Background: Recent advancements in large language models (LLMs) offer potential benefits in healthcare, particularly in processing extensive patient records. However, existing benchmarks do not fully assess LLMs' capability in handling…

Social determinants of health (SDoH) have an important impact on patient outcomes but are incompletely collected from the electronic health records (EHR). This study researched the ability of large language models to extract SDoH from free…

Effective patient-provider communication is crucial in clinical care, directly impacting patient outcomes and quality of life. Traditional evaluation methods, such as human ratings, patient feedback, and provider self-assessments, are often…

计算与语言 · 计算机科学 2024-09-25 Zhiyuan Wang , Fangxu Yuan , Virginia LeBaron , Tabor Flickinger , Laura E. Barnes

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

计算机与社会 · 计算机科学 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

计算与语言 · 计算机科学 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

We present MedCOD (Medical Chain-of-Dictionary), a hybrid framework designed to improve English-to-Spanish medical translation by integrating domain-specific structured knowledge into large language models (LLMs). MedCOD integrates…

计算与语言 · 计算机科学 2025-09-22 Md Shahidul Salim , Lian Fu , Arav Adikesh Ramakrishnan , Zonghai Yao , Hong Yu

We aim to present a comprehensive overview of the latest advancements in utilizing Large Language Models (LLMs) within the healthcare sector, emphasizing their transformative impact across various medical domains. LLMs have become pivotal…

计算与语言 · 计算机科学 2026-04-07 Ummara Mumtaz , Awais Ahmed , Summaya Mumtaz

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

计算与语言 · 计算机科学 2026-01-15 Mojdeh Rahmanian , Seyed Mostafa Fakhrahmad , Seyedeh Zahra Mousavi

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

定量方法 · 定量生物学 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

Determining which legal cases are relevant to a given query involves navigating lengthy texts and applying nuanced legal reasoning. Traditionally, this task has demanded significant time and domain expertise to identify key Legal Facts and…

人工智能 · 计算机科学 2025-08-15 Shengjie Ma , Qi Chu , Jiaxin Mao , Xuhui Jiang , Haozhe Duan , Chong Chen

Clinical notes are an efficient way to record patient information but are notoriously hard to decipher for non-experts. Automatically simplifying medical text can empower patients with valuable information about their health, while saving…

Clinical oncology generates vast, unstructured data that often contain inconsistencies, missing information, and ambiguities, making it difficult to extract reliable insights for data-driven decision-making. General-purpose large language…

计算与语言 · 计算机科学 2025-03-12 Morteza Rohanian , Tarun Mehra , Nicola Miglino , Farhad Nooralahzadeh , Michael Krauthammer , Andreas Wicki