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Determining clinically relevant physiological states from multivariate time series data with missing values is essential for providing appropriate treatment for acute conditions such as Traumatic Brain Injury (TBI), respiratory failure, and…

机器学习 · 计算机科学 2024-03-29 Hamid Ghaderi , Brandon Foreman , Amin Nayebi , Sindhu Tipirneni , Chandan K. Reddy , Vignesh Subbian

Self-supervised learning approaches provide a promising direction for clustering multivariate time-series data. However, real-world time-series data often include missing values, and the existing approaches require imputing missing values…

机器学习 · 计算机科学 2023-05-30 Hamid Ghaderi , Brandon Foreman , Amin Nayebi , Sindhu Tipirneni , Chandan K. Reddy , Vignesh Subbian

Clustering time-series data in healthcare is crucial for clinical phenotyping to understand patients' disease progression patterns and to design treatment guidelines tailored to homogeneous patient subgroups. While rich temporal dynamics…

机器学习 · 计算机科学 2023-02-27 Yuchao Qin , Mihaela van der Schaar , Changhee Lee

Baseline injury categorization is important to traumatic brain injury (TBI) research and treatment. Current categorization is dominated by symptom-based scores that insufficiently capture injury heterogeneity. In this work, we apply…

机器学习 · 计算机科学 2018-12-04 Aaron J. Masino , Kaitlin A. Folweiler

Traumatic brain injury (TBI) is intrinsically heterogeneous, and typical clinical outcome measures like the Glasgow Coma Scale complicate this diversity. The large variability in severity and patient outcomes render it difficult to link…

Prognoses of Traumatic Brain Injury (TBI) outcomes are neither easily nor accurately determined from clinical indicators. This is due in part to the heterogeneity of damage inflicted to the brain, ultimately resulting in diverse and complex…

Traumatic Brain Injury (TBI) is a major contributor to mortality among older adults, with geriatric patients facing disproportionately high risk due to age-related physiological vulnerability and comorbidities. Early and accurate prediction…

定量方法 · 定量生物学 2025-05-23 Yong Si , Junyi Fan , Li Sun , Shuheng Chen , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

The accurate prognosis for traumatic brain injury (TBI) patients is difficult yet essential to inform therapy, patient management, and long-term after-care. Patient characteristics such as age, motor and pupil responsiveness, hypoxia and…

In this paper, we introduce a new dataset in the medical field of Traumatic Brain Injury (TBI), called TBI-IT, which includes both electronic medical records (EMRs) and head CT images. This dataset is designed to enhance the accuracy of…

图像与视频处理 · 电气工程与系统科学 2024-03-15 Jie Li , Jiaying Wen , Tongxin Yang , Fenglin Cai , Miao Wei , Zhiwei Zhang , Li Jiang

Existing methods to characterise the evolving condition of traumatic brain injury (TBI) patients in the intensive care unit (ICU) do not capture the context necessary for individualising treatment. Here, we integrate all heterogenous data…

Stroke is a leading cause of neurological injury characterized by impairments in multiple neurological domains including cognition, language, sensory and motor functions. Clinical recovery in these domains is tracked using a wide range of…

定量方法 · 定量生物学 2021-10-01 Sanjukta Krishnagopal , Keith Lohse , Robynne Braun

Traumatic Brain Injury (TBI) is a common cause of death and disability. However, existing tools for TBI diagnosis are either subjective or require extensive clinical setup and expertise. The increasing affordability and reduction in size of…

信号处理 · 电气工程与系统科学 2021-02-01 Navjodh Singh Dhillon , Agustinus Sutandi , Manoj Vishwanath , Miranda M. Lim , Hung Cao , Dong Si

Traumatic brain injury (TBI) presents a significant public health challenge, often resulting in mortality or lasting disability. Predicting outcomes such as mortality and Functional Status Scale (FSS) scores can enhance treatment strategies…

Due to the wider availability of modern electronic health records, patient care data is often being stored in the form of time-series. Clustering such time-series data is crucial for patient phenotyping, anticipating patients' prognoses by…

医学物理 · 物理学 2020-06-17 Changhee Lee , Mihaela van der Schaar

Multivariate Time-Series (MTS) clustering is crucial for signal processing and data analysis. Although deep learning approaches, particularly those leveraging Contrastive Learning (CL), are prominent for MTS representation, existing…

机器学习 · 计算机科学 2026-01-13 Zexi Tan , Tao Xie , Haoyi Xiao , Baoyao Yang , Yuzhu Ji , An Zeng , Xiang Zhang , Yiqun Zhang

The segmentation of lesions in Moderate to Severe Traumatic Brain Injury (msTBI) presents a significant challenge in neuroimaging due to the diverse characteristics of these lesions, which vary in size, shape, and distribution across brain…

计算机视觉与模式识别 · 计算机科学 2025-04-10 Constantin Ulrich , Tassilo Wald , Fabian Isensee , Klaus H. Maier-Hein

Patient stratification identifying clinically meaningful subgroups is essential for advancing personalized medicine through improved diagnostics and treatment strategies. Electronic health records (EHRs), particularly those from intensive…

机器学习 · 计算机科学 2025-06-09 Dimitrios Proios , Alban Bornet , Anthony Yazdani , Jose F Rodrigues , Douglas Teodoro

Traumatic brain injury (TBI) is a complex injury that is hard to predict and diagnose, with many studies focused on associating head kinematics to brain injury risk. Recently, there has been a push towards using computationally expensive…

The identification and segmentation of moderate-severe traumatic brain injury (TBI) lesions pose a significant challenge in neuroimaging. This difficulty arises from the extreme heterogeneity of these lesions, which vary in size, number,…

计算机视觉与模式识别 · 计算机科学 2025-09-30 Ghanshyam Dhamat , Vaanathi Sundaresan

Patients with traumatic brain injury (TBI) often experience pathological increases in intracranial pressure (ICP), leading to intracranial hypertension (tIH), a common and serious complication. Early warning of an impending rise in ICP…

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