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Epidemic outbreaks are an important healthcare challenge, especially in developing countries where they represent one of the major causes of mortality. Approaches that can rapidly target subpopulations for surveillance and control are…

Orofacial deficits are common in people with Parkinson's disease (PD) and their evolution might represent an important biomarker of disease progression. We are developing an automated system for assessment of orofacial function in PD that…

Living systems exhibit complex yet organized behavior on multiple spatiotemporal scales. To investigate the nature of multiscale coordination in living systems, one needs a meaningful and systematic way to quantify the complex dynamics, a…

The accelerometer has become an almost ubiquitous device, providing enormous opportunities in healthcare monitoring beyond step counting or other average energy estimates in 15-60 second epochs. Objective: To develop an open data set with…

The spread of COVID-19 has been greatly impacted by regulatory policies and behavior patterns that vary across counties, states, and countries. Population-level dynamics of COVID-19 can generally be described using a set of ordinary…

Parkinson's disease (PD) is a slowly progressive, debilitating neurodegenerative disease which causes motor symptoms including gait dysfunction. Motor fluctuations are alterations between periods with a positive response to levodopa therapy…

A deep latent variable model is a powerful method for capturing complex distributions. These models assume that underlying structures, but unobserved, are present within the data. In this dissertation, we explore high-dimensional problems…

As robots become more common for both able-bodied individuals and those living with a disability, it is increasingly important that lay people be able to drive multi-degree-of-freedom platforms with low-dimensional controllers. One approach…

Depression is a complex mental disorder characterized by a diverse range of observable and measurable indicators that go beyond traditional subjective assessments. Recent research has increasingly focused on objective, passive, and…

While physical activity has been described as a primary prevention against chronic diseases, strenuous physical exertion under adverse ambient conditions has also been reported as a major contributor to exacerbation of chronic respiratory…

Chronic respiratory diseases, such as chronic obstructive pulmonary disease and asthma, are a serious health crisis, affecting a large number of people globally and inflicting major costs on the economy. Current methods for assessing the…

The estimation of functional networks through functional covariance and graphical models have recently attracted increasing attention in settings with high dimensional functional data, where the number of functional variables p is…

Critical infrastructure systems must be both robust and resilient in order to ensure the functioning of society. To improve the performance of such systems, we often use risk and vulnerability analysis to find and address system weaknesses.…

This report relates to a study group hosted by the EPSRC funded network, Integrating data-driven BIOphysical models into REspiratory MEdicine (BIOREME), and supported by SofTMech and Innovate UK, Business Connect. This report summarises the…

We investigate how both the adaptation of a generic foundation model via transfer learning and the integration of complementary modalities from the operating room (OR) can support surgical data science. To this end, we use V-JEPA as the…

Human mobility data accumulated from Point-of-Interest (POI) check-ins provides great opportunity for user behavior understanding. However, data quality issues (e.g., geolocation information missing, unreal check-ins, data sparsity) in…

Evaluating neurological disorders such as Parkinson's disease (PD) is a challenging task that requires the assessment of several motor and non-motor functions. In this paper, we present an end-to-end deep learning framework to measure PD…

Our research focuses on analysing human activities according to a known behaviorist scenario, in case of noisy and high dimensional collected data. The data come from the monitoring of patients with dementia diseases by wearable cameras. We…

Integrating diverse data sources offers a comprehensive view of patient health and holds potential for improving clinical decision-making. In Cystic Fibrosis (CF), which is a genetic disorder primarily affecting the lungs, biomarkers that…

Contactless monitoring using thermal imaging has become increasingly proposed to monitor patient deterioration in hospital, most recently to detect fevers and infections during the COVID-19 pandemic. In this letter, we propose a novel…