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Objective: The design of an Artificial Pancreas (AP) to regulate blood glucose levels requires reliable control methods. Model Predictive Control has emerged as a promising approach for glycemia control. However, model--based control…

最优化与控制 · 数学 2022-02-02 Claudia Lopez-Zazueta , Øyvind Stavdahl , Anders Lyngvi Fougner

This paper explores the application of reinforcement learning to optimize the parameters of a Type-1 Takagi-Sugeno fuzzy controller, designed to operate as an artificial pancreas for Type 1 diabetes. The primary challenge in diabetes…

系统与控制 · 电气工程与系统科学 2025-03-11 Omar Mameche , Abdelhadi Abedou , Taqwa Mezaache , Mohamed Tadjine

AI procedures joined with wearable gadgets can convey exact transient blood glucose level forecast models. Also, such models can learn customized glucose-insulin elements dependent on the sensor information gathered by observing a few parts…

机器学习 · 计算机科学 2021-01-22 Ignacio Rodriguez

Around a third of type 2 diabetes patients (T2D) are escalated to basal insulin injections. Basal insulin dose is titrated to achieve a tight glycemic target without undue hypoglycemic risk. In the standard of care (SoC), titration is based…

系统与控制 · 电气工程与系统科学 2023-09-19 Anas El Fathi , Mohammadreza Ganji , Dimitri Boiroux , Henrik Bengtsson , Marc D. Breton

The adoption of deep learning in healthcare is hindered by their "black box" nature. In this paper, we explore the RETAIN architecture for the task of glusose forecasting for diabetic people. By using a two-level attention mechanism, the…

机器学习 · 计算机科学 2020-09-09 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Background: Type 2 diabetes (T2D) is a prevalent chronic disease with a significant risk of serious health complications and negative impacts on the quality of life. Given the impact of individual characteristics and lifestyle on the…

机器学习 · 计算机科学 2024-01-08 Syed Hasib Akhter Faruqui , Adel Alaeddini , Yan Du , Shiyu Li , Kumar Sharma , Jing Wang

The purpose of this Conference is to present the main lines of base projects that are founded on research already begun in previous years. In this sense, this manuscript will present the main lines of research in Diabetes Mellitus type 1…

机器学习 · 计算机科学 2021-01-08 Ignacio Rodriguez

The data mining along with emerging computing techniques have astonishingly influenced the healthcare industry. Researchers have used different Data Mining and Internet of Things (IoT) for enrooting a programmed solution for diabetes and…

计算机与社会 · 计算机科学 2019-01-31 M. Sharma , G. Singh , R. Singh

We investigate the consequences of periodic, on-off glucose infusion on the glucose-insulin regulatory system on the basis of a system-level mathematical model with two explicit time delays. Studying the effects of such infusion protocols…

动力系统 · 数学 2023-10-05 Stefan Ruschel , Benoit Huard

Pramlintide's capability to delay gastric emptying has motivated its use in artificial pancreas systems, accompanying insulin as a control action. Due to the scarcity of pramlintide simulation models in the literature, in silico testing of…

系统与控制 · 电气工程与系统科学 2025-06-24 Borja Pons Torres , Iván Sala Mira , Clara Furió-Novejarque , Ricardo Sanz , Pedro García , José-Luis Díez , Jorge Bondia

Diabetes-related foot ulcers and complications are a significant concern for individuals with diabetes, leading to severe health implications such as lower-limb amputation and reduced quality of life. This chapter discusses applying…

计算机与社会 · 计算机科学 2023-09-26 Sayed Ahmed , Muhammad Ashad Kabir , Muhammad E. H. Chowdhury , Susan Nancarrow

This paper considers the problem of Bayesian optimization for systems with safety-critical constraints, where both the objective function and the constraints are unknown, but can be observed by querying the system. In safety-critical…

最优化与控制 · 数学 2022-05-06 Dinesh Krishnamoorthy , Francis J. Doyle

Diabetes, a chronic condition that impairs how the body turns food into energy, i.e. blood glucose, affects 38 million people in the US alone. The standard treatment is to supplement carbohydrate intake with an artificial pancreas, i.e. a…

定量方法 · 定量生物学 2025-08-26 Ashok Khanna , Olivier Francon , Risto Miikkulainen

Diabetes impacts the quality of life of millions of people. However, diabetes diagnosis is still an arduous process, given that the disease develops and gets treated outside the clinic. The emergence of wearable medical sensors (WMSs) and…

计算机视觉与模式识别 · 计算机科学 2019-10-14 Hongxu Yin , Bilal Mukadam , Xiaoliang Dai , Niraj K. Jha

Diabetes is a chronic metabolic disorder characterized by elevated blood glucose levels due to impaired insulin production or function. Two main forms are recognized: type 1 diabetes (T1D), which involves autoimmune destruction of…

基因组学 · 定量生物学 2026-02-11 Maria De La Luz Lomboy Toledo , Daniel Onah

The Internet of Things (IoT) revolutionizes smart city domains such as healthcare, transportation, industry, and education. The Internet of Medical Things (IoMT) is gaining prominence, particularly in smart hospitals and Remote Patient…

分布式、并行与集群计算 · 计算机科学 2025-02-25 Alain Hennebelle , Qifan Dieng , Leila Ismail , Rajkumar Buyya

With the increasing availability of wearable devices, continuous monitoring of individuals' physiological and behavioral patterns has become significantly more accessible. Access to these continuous patterns about individuals' statuses…

The dead-in-bed syndrome describes the sudden and unexplained death of young individuals with Type 1 Diabetes (T1D) without prior long-term complications. One leading hypothesis attributes this phenomenon to nocturnal hypoglycemia (NH), a…

机器学习 · 计算机科学 2025-04-15 Marco Voegeli , Sonia Laguna , Heike Leutheuser , Marc Pfister , Marie-Anne Burckhardt , Julia E Vogt

In the U.S., over a third of adults are pre-diabetic, with 80\% unaware of their status. This underlines the need for better glucose monitoring to prevent type 2 diabetes and related heart diseases. Existing wearable glucose monitors are…

信号处理 · 电气工程与系统科学 2024-06-26 Yidong Zhu , Nadia B Aimandi , Mohammad Arif Ul Alam

Quantum state transformations that are robust to experimental imperfections are important for applications in quantum information science and quantum sensing. Counterdiabatic (CD) approaches, which use knowledge of the underlying system…

量子气体 · 物理学 2020-11-10 Eric J. Meier , Kinfung Ngan , Dries Sels , Bryce Gadway