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相关论文: Enhancing the Study of Quantal Exocytotic Events: …

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A microstructured graphitic 4x4 multielectrode array was embedded in a single crystal diamond substrate (4x4 {uG-SCD MEA) for real-time monitoring of exocytotic events from cultured chromaffin cells and adrenal slices. The current approach…

仪器与探测器 · 物理学 2016-08-26 F. Picollo , A. Battiato , E. Bernardi , A. Marcantoni , A. Pasquarelli , E. Carbone , P. Olivero , V. Carabelli

The detection of quantal exocytic events from neurons and neuroendocrine cells is a challenging task in neuroscience. One of the most promising platforms for the development of a new generation of biosensors is diamond, due to its…

仪器与探测器 · 物理学 2016-08-30 F. Picollo , A. Battiato , E. Carbone , L. Croin , E. Enrico , J. Forneris , S. Gosso , P. Olivero , A. Pasquarelli , V. Carabelli

We report on the ion beam fabrication of all-carbon multi electrode arrays (MEAs) based on 16 graphitic micro-channels embedded in single-crystal diamond (SCD) substrates. The fabricated SCD-MEAs are systematically employed for the in vitro…

Considering the variability of amplitude and phase patterns in electrocardiogram (ECG) signals due to cardiac activity and individual differences, existing entropy-based studies have not fully utilized these two patterns and lack…

信号处理 · 电气工程与系统科学 2024-04-16 Shuaicong Hu , Yanan Wang , Jian Liu , Jingyu Lin , Shengmei Qin , Zhenning Nie , Zhifeng Yao , Wenjie Cai , Cuiwei Yang

The electronic band structure, describing the motion and interactions of electrons in materials, dictates the electrical, optical, and thermodynamic properties of solids. Angle-resolved photoemission spectroscopy (ARPES) provides a direct…

The quantal release of catecholamines from neuroendocrine cells is a key mechanism which has been investigated with a broad range of materials and devices, among which carbon-based materials such as carbon fibers, diamond-like carbon,…

We present an algorithm to identify individual neural spikes observed on high-density multi-electrode arrays (MEAs). Our method can distinguish large numbers of distinct neural units, even when spikes overlap, and accounts for intrinsic…

神经元与认知 · 定量生物学 2013-08-01 Jason S. Prentice , Jan Homann , Kristina D. Simmons , Gašper Tkačik , Vijay Balasubramanian , Philip C. Nelson

Elucidating exocytosis processes provide insights into cellular neurotransmission mechanisms, and may have potential in neurodegenerative diseases research. Amperometry is an established electrochemical method for the detection of…

亚细胞过程 · 定量生物学 2023-02-07 Jeyashree Krishnan , Zeyu Lian , Pieter E. Oomen , Xiulan He , Soodabeh Majdi , Andreas Schuppert , Andrew Ewing

Photon echo (PE) techniques offer a promising approach to optical quantum memory, yet their implementation in conventional platforms, such as rare-earth-ion-doped crystals, is hindered by limited bandwidths. Semiconductor quantum dot (QD)…

Advanced Persistent Threats (APTs) are sophisticated, long-term cyberattacks that are difficult to detect because they operate stealthily and often blend into normal system behavior. This paper presents a neuro-symbolic anomaly detection…

机器学习 · 计算机科学 2026-02-17 Asif Tauhid , Sidahmed Benabderrahmane , Mohamad Altrabulsi , Ahamed Foisal , Talal Rahwan

Rationale: Computer aided detection (CAD) algorithms for Pulmonary Embolism (PE) algorithms have been shown to increase radiologists' sensitivity with a small increase in specificity. However, CAD for PE has not been adopted into clinical…

Microfluidic Live-Cell Imaging (MLCI) yields data on microbial cell factories. However, continuous acquisition is challenging as high-throughput experiments often lack real-time insights, delaying responses to stochastic events. We…

In the context of high-quality asteroseismic data provided by the NASA Kepler mission, we developed a new code, termed Diamonds (high-DImensional And multi-MOdal NesteD Sampling), for fast Bayesian parameter estimation and model comparison…

天体物理仪器与方法 · 物理学 2015-10-21 Enrico Corsaro , Joris De Ridder

Repeating a gate sequence multiple times amplifies systematic errors coherently, making it a useful tool for characterizing quantum gates. However, the precision of such an approach is limited by low-frequency noises, while its efficiency…

Color centers in diamond play a central role in the development of quantum photonic technologies, and their importance is only expected to grow in the near future. For many quantum applications, high collection efficiency from individual…

Wearable electrocardiograph (ECG) recording and processing systems have been developed to detect cardiac arrhythmia to help prevent heart attacks. Conventional wearable systems, however, suffer from high energy consumption at both circuit…

信号处理 · 电气工程与系统科学 2022-05-27 Jinbo Chen , Fengshi Tian , Jie Yang , Mohamad Sawan

Fully Homomorphic Encryption (FHE) is a promising privacy-preserving technology enabling secure computation over encrypted data. A major limitation of current FHE schemes is their high runtime overhead. As a result, automatic optimization…

密码学与安全 · 计算机科学 2025-06-17 Julien de Castelnau , Mingfei Yu , Giovanni De Micheli

Maximal Clique Enumeration (MCE) is a fundamental graph mining problem, and is useful as a primitive in identifying dense structures in a graph. Due to the high computational cost of MCE, parallel methods are imperative for dealing with…

分布式、并行与集群计算 · 计算机科学 2020-01-31 Apurba Das , Seyed-Vahid Sanei-Mehri , Srikanta Tirthapura

Background: Electroencephalography (EEG) monitors brain activity during sleep and is used to identify sleep disorders. In sleep medicine, clinicians interpret raw EEG signals in so-called sleep stages, which are assigned by experts to every…

信号处理 · 电气工程与系统科学 2018-12-12 Stanislas Chambon , Valentin Thorey , Pierrick J. Arnal , Emmanuel Mignot , Alexandre Gramfort

We present a graphical, knowledge-based method for reviewing treatment-emergent adverse events (AEs) in clinical trials. The approach enhances MedDRA by adding a hidden medical knowledge layer (Safeterm) that captures semantic relationships…

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