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In the past decades, absorption modalities have emerged as powerful tools for label-free functional and structural imaging of cells and tissues. Many biomolecules present unique absorption spectra providing chromophore-specific information…

Exposure to laser light alters cell culture examination via optical microscopic imaging techniques, also based on label-free coherent digital holography. To mitigate this detrimental feature, researchers tend to use a broader spectrum and…

The emergence of optical circular dichroism in chiral nanoscale and molecular systems provides not only a way for analyzing the sample chirality itself but also additional degrees of freedom in manipulating light. Such manipulation can be…

介观与纳米尺度物理 · 物理学 2026-02-18 Marek Zálešák , Martin Ošmera , Martin Hrtoň , Andrea Konečná

The photon counting imaging paradigm in the visible and the infrared comes from the very small energy carried by a single photon at these wavelengths. Usually to detect photons the photoelectric effect is used. It converts a photon to a…

天体物理仪器与方法 · 物理学 2022-07-28 Jean-Luc Gach , Isaure De Kernier , Philippe Feautrier

A technique of pulsed low-energy electron holography is introduced that allows for recording highly resolved holograms within reduced exposure times. Therefore, stacks of holograms are accumulated in a pulsed mode with individual…

仪器与探测器 · 物理学 2013-05-27 Matthias Germann , Tatiana Latychevskaia , Conrad Escher , Hans-Werner Fink

The industry of wearable remote health monitoring system keeps growing. In the diagnosis of cardiovascular disease, Electrocardiography~(ECG) waveform is one of the major tools which is thus widely taken as the monitoring objective. For the…

信息论 · 计算机科学 2017-04-07 Pengda Huang

Redox monolayers are the base for a wide variety of devices including high-frequency molecular diodes or biomolecular sensors. We introduce a formalism to describe the electrochemical shot-noise of such monolayer, confirmed experimentally…

介观与纳米尺度物理 · 物理学 2023-06-05 Simon Grall , Shuo Li , Laurent Jalabert , Soo-Hyeon Kim , Arnaud Chovin , Christophe Demaille , Nicolas Clement

Control of components in integrated photonic circuits is crucial in achieving programmable devices. Operation bandwidth of a plasmonic device cannot be generally tuned once it is manufactured, especially in the visible regime. Here, we…

光学 · 物理学 2024-03-22 Hira Asif , Alpan Bek , Mehmet Emre Tasgin , Ramazan Sahin

Progress in electron-beam spectroscopies has recently enabled the study of optical excitations with combined space, energy and time resolution in the nanometer, millielectronvolt and femtosecond domain, thus providing unique access into…

光学 · 物理学 2019-11-13 Albert Polman , Mathieu Kociak , F. Javier García de Abajo

We demonstrate an electro-optic wide-field method to enable fluorescence lifetime microscopy (FLIM) with high throughput and single-molecule sensitivity. Resonantly driven Pockels cells are used to efficiently gate images at 39 MHz,…

光学 · 物理学 2021-09-23 Adam J. Bowman , Mark A. Kasevich

Aberration-corrected Scanning Transmission Electron Microscopy (STEM) has become an essential tool in understanding materials at the atomic scale. However, tuning the aberration corrector to produce a sub-{\AA}ngstr\"om probe is a complex…

Ultrashort light pulses are ubiquitous in modern research, but the electromagnetic field of the optical cycles is usually not easy to obtain as a function of time. Field-resolved pulse characterization requires either a nonlinear-optical…

光学 · 物理学 2022-11-30 Yuya Morimoto , Bo-Han Chen , Peter Baum

We demonstrated a CMOS imaging system that adapts each pixel's exposure and sampling rate to capture high dynamic range (HDR) videos. The system consist of a custom designed image sensor with pixel-wise exposure configurability and a…

图像与视频处理 · 电气工程与系统科学 2019-06-25 Jie , Zhang , Jonathan P. Newman , Xiao Wang , Chetan Singh Thakur , John Rattray , Ralph Etienne-Cummings , Matthew A. Wilson

To overcome the physical barriers caused by light diffraction, super-resolution techniques are often applied in fluorescence microscopy. State-of-the-art approaches require specific and often demanding acquisition conditions to achieve…

Transmission electron microscopy at very low energy is a promising way to avoid damaging delicate biological samples with the incident electrons, a known problem in conventional transmission electron microscopy. For imaging in the 0-30 eV…

材料科学 · 物理学 2020-09-22 Peter S. Neu , Daniël Geelen , Aniket Thete , Rudolf M. Tromp , Sense Jan van der Molen

Recovering both amplitude and phase information from a system is a fundamental goal of optical imaging. At the same time, it is crucial to operate at low photon doses to avoid altering the sample, particularly in biological applications.…

量子物理 · 物理学 2026-01-15 Alberto Paniate , Giuseppe Ortolano , Sarika Soman , Marco Genovese , Ivano Ruo-Berchera

Electrochemistry exploits local current heterogeneities at various scales ranging from the micrometer to the nanometer. The last decade has witnessed unprecedented progress in the development of a wide range of electroanalytical techniques…

光学 · 物理学 2022-11-16 Frederic Kanoufi

Employing electro-optic sampling (EOS) with ultrashort probe pulses, recent experiments showed direct measurements of quantum vacuum fields and their correlations on subcycle timescales. Here, we propose a quantum-enhanced EOS where…

量子物理 · 物理学 2022-01-12 Stéphane Virally , Patrick Cusson , Denis V. Seletskiy

We report on a narrow linewidth laser diode system that is stabilized using both optical and electronic feedback to a spectral hole in cryogenic Tm:YAG. The laser system exhibits very low phase noise. The spectrum of the beat signal between…

In high-contrast space-based coronagraphs, one of the main limiting factors for imaging the dimmest exoplanets is the time varying nature of the residual starlight (speckles). Modern methods try to differentiate between the intensities of…

天体物理仪器与方法 · 物理学 2019-09-04 Leonid Pogorelyuk , N. Jeremy Kasdin , Clarence W. Rowley