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Substantial advances in multi-modal Artificial Intelligence (AI) facilitate the combination of diverse medical modalities to achieve holistic health assessments. We present COMPRER , a novel multi-modal, multi-objective pretraining…

计算机视觉与模式识别 · 计算机科学 2024-03-18 Guy Lutsker , Hagai Rossman , Nastya Godiva , Eran Segal

The goal of this paper is to develop a measure for characterizing complex dependence between stationary time series that cannot be captured by traditional measures such as correlation and coherence. Our approach is to use copula models of…

统计方法学 · 统计学 2018-09-26 Charles Fontaine , Ron D. Frostig , Hernando Ombao

The increasing use of large language models in mental health applications calls for principled evaluation frameworks that assess alignment with psychotherapeutic best practices beyond surface-level fluency. While recent systems exhibit…

计算与语言 · 计算机科学 2026-04-15 Abdullah Mazhar , Het Riteshkumar Shah , Aseem Srivastava , Smriti Joshi , Md Shad Akhtar

Objectives: Administrative data is commonly used to inform chronic disease prevalence and support health informatics research. This study assessed the validity of coding comorbidity in the International Classification of Diseases, 10th…

定量方法 · 定量生物学 2025-04-02 Jie Pan , Seungwon Lee , Cheligeer Cheligeer , Bing Li , Guosong Wu , Catherine A Eastwood , Yuan Xu , Hude Quan

Normative models of brain structure estimate the effects of covariates such as age and sex using large samples of healthy controls. These models can then be applied to e.g. smaller clinical cohorts to distinguish disease effects from other…

A computer-aided interpretation approach is proposed to detect rheumatic arthritis (RA) of human finger joints in optical tomographic images. The image interpretation method employs a multi-variate signal detection analysis aided by a…

Continuous biomarkers are common for disease screening and diagnosis. To reach a dichotomous clinical decision, a threshold would be imposed to distinguish subjects with disease from non-diseased individuals. Among various performance…

统计方法学 · 统计学 2021-04-21 Ziyi Li , Yijuan Huang , Dattatraya Patil , Martin G. Sanda

AI-assisted radiological interpretation is based on predominantly narrow, single-task models. This approach is impractical for covering the vast spectrum of imaging modalities, diseases, and radiological findings. Foundation models (FMs)…

Anomaly detection and localization in medical imaging remain critical challenges in healthcare. This paper introduces Spatial-MSMA (Multiscale Score Matching Analysis), a novel unsupervised method for anomaly localization in volumetric…

计算机视觉与模式识别 · 计算机科学 2024-07-19 Ahsan Mahmood , Junier Oliva , Martin Styner

Studies show that Studies that cardiovascular diseases (CVDs) are malignant for human health. Thus, it is important to have an efficient way of CVD prognosis. In response to this, the healthcare industry has adopted machine learning-based…

机器学习 · 计算机科学 2022-08-02 Mohammed Nowshad Ruhani Chowdhury , Wandong Zhang , Thangarajah Akilan

As data shift or new data become available, updating clinical machine learning models may be necessary to maintain or improve performance over time. However, updating a model can introduce compatibility issues when the behavior of the…

机器学习 · 统计学 2023-08-11 Erkin Ötleş , Brian T. Denton , Jenna Wiens

In this study, we utilized statistical analysis and machine learning methods to examine whether rehabilitation exercises can improve patients post-stroke functional abilities, as well as forecast the improvement in functional abilities. Our…

Despite the growing promise of artificial intelligence (AI) in supporting decision-making across domains, fostering appropriate human reliance on AI remains a critical challenge. In this paper, we investigate the utility of exploring…

人机交互 · 计算机科学 2025-05-26 Min Hun Lee , Martyn Zhe Yu Tok

Alzheimer's disease (AD) is the most common type of dementia accompanied with brain atrophy. Structural measurements of brain atrophy in specific brain structures such as hippocampus using magnetic resonance imaging (MRI) have been reported…

医学物理 · 物理学 2016-05-10 Kenya Murase , Naohiko Gondo , Tsutomu Soma

The integration of artificial intelligence (AI) into medical diagnostic workflows requires robust and consistent evaluation methods to ensure reliability, clinical relevance, and the inherent variability in expert judgments. Traditional…

Introduction: Bone health disorders like osteoarthritis and osteoporosis pose major global health challenges, often leading to delayed diagnoses due to limited diagnostic tools. This study presents an AI-powered system that analyzes knee…

Unrecognized patient deterioration can lead to high morbidity and mortality. Most existing deterioration prediction models require a large number of clinical information, typically collected in hospital settings, such as medical images or…

机器学习 · 计算机科学 2023-09-06 Sarmad Mehrdad , Farah E. Shamout , Yao Wang , S. Farokh Atashzar

In the last decade, machine learning techniques have gained popularity for estimating causal effects. One machine learning approach that can be used for estimating an average treatment effect is Double/debiased machine learning (DML)…

计量经济学 · 经济学 2025-01-17 Daniele Ballinari , Nora Bearth

Speech, language, and communication deficits are present in most neurodegenerative syndromes. They enable the early detection, diagnosis, treatment planning, and monitoring of neurocognitive disease progression as part of traditional…

计算与语言 · 计算机科学 2023-12-07 Charalambos Themistocleous , Kyrana Tsapkini , Dimitrios Kokkinakis

Precision rehabilitation offers the promise of an evidence-based approach for optimizing individual rehabilitation to improve long-term functional outcomes. Emerging techniques, including those driven by artificial intelligence, are rapidly…

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