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Multiple hypothesis testing practices vary widely, without consensus on which are appropriate when. This paper provides an economic foundation for these practices designed to capture leading examples, such as regulatory approval on the…

综合经济学 · 经济学 2026-02-19 Davide Viviano , Kaspar Wuthrich , Paul Niehaus

Machine learning classification tasks often benefit from predicting a set of possible labels with confidence scores to capture uncertainty. However, existing methods struggle with the high-dimensional nature of the data and the lack of…

机器学习 · 计算机科学 2024-07-08 Rui Luo , Zhixin Zhou

Conformal prediction is a framework for uncertainty quantification that constructs prediction sets for previously unseen data, guaranteeing coverage of the true label with a specified probability. However, the efficiency of these prediction…

机器学习 · 计算机科学 2026-01-06 Erfan Hajihashemi , Yanning Shen

We develop a new approach to multi-label conformal prediction in which we aim to output a precise set of promising prediction candidates with a bounded number of incorrect answers. Standard conformal prediction provides the ability to adapt…

机器学习 · 计算机科学 2022-02-16 Adam Fisch , Tal Schuster , Tommi Jaakkola , Regina Barzilay

Hierarchical inference in (generalized) regression problems is powerful for finding significant groups or even single covariates, especially in high-dimensional settings where identifiability of the entire regression parameter vector may be…

统计方法学 · 统计学 2021-10-22 Claude Renaux , Peter Bühlmann

During multiple testing, researchers often adjust their alpha level to control the familywise error rate for a statistical inference about a joint union alternative hypothesis (e.g., "H1,1 or H1,2"). However, in some cases, they do not make…

统计方法学 · 统计学 2024-04-04 Mark Rubin

As large language models continue to be widely developed, robust uncertainty quantification techniques will become crucial for their safe deployment in high-stakes scenarios. In this work, we explore how conformal prediction can be used to…

计算与语言 · 计算机科学 2023-07-11 Bhawesh Kumar , Charlie Lu , Gauri Gupta , Anil Palepu , David Bellamy , Ramesh Raskar , Andrew Beam

Machine learning applications frequently come with multiple diverse objectives and constraints that can change over time. Accordingly, trained models can be tuned with sets of hyper-parameters that affect their predictive behavior (e.g.,…

机器学习 · 计算机科学 2022-10-17 Bracha Laufer-Goldshtein , Adam Fisch , Regina Barzilay , Tommi Jaakkola

Recent advances have shown that statistical tests for the rank of cross-covariance matrices play an important role in causal discovery. These rank tests include partial correlation tests as special cases and provide further graphical…

机器学习 · 计算机科学 2025-06-13 Xinshuai Dong , Ignavier Ng , Boyang Sun , Haoyue Dai , Guang-Yuan Hao , Shunxing Fan , Peter Spirtes , Yumou Qiu , Kun Zhang

Typically, machine learning models are trained and evaluated without making any distinction between users (e.g, using traditional hold-out and cross-validation). However, this produces inaccurate performance metrics estimates in multi-user…

机器学习 · 计算机科学 2023-12-11 Enrique Garcia-Ceja , Luciano Garcia-Banuelos , Nicolas Jourdan

Diagnostic accuracy studies assess sensitivity and specificity of a new index test in relation to an established comparator or the reference standard. The development and selection of the index test is usually assumed to be conducted prior…

统计方法学 · 统计学 2022-08-30 Max Westphal , Antonia Zapf

Current statistical inference problems in areas like astronomy, genomics, and marketing routinely involve the simultaneous testing of thousands -- even millions -- of null hypotheses. For high-dimensional multivariate distributions, these…

统计方法学 · 统计学 2017-04-25 Weixin Cai , Nima S. Hejazi , Alan E. Hubbard

This paper tackles the challenge of performing multiple quantile regressions across different quantile levels and the associated problem of controlling the familywise error rate, an issue that is generally overlooked in practice. We propose…

统计方法学 · 统计学 2026-04-10 Riccardo De Santis , Anna Vesely , Angela Andreella

Two common concerns raised in analyses of randomized experiments are (i) appropriately handling issues of non-compliance, and (ii) appropriately adjusting for multiple tests (e.g., on multiple outcomes or subgroups). Although simple…

统计方法学 · 统计学 2016-05-25 Joseph J. Lee , Laura Forastiere , Luke Miratrix , Natesh S. Pillai

Conformalized multiple testing offers a model-free way to control predictive uncertainty in decision-making. Existing methods typically use only part of the available data to build score functions tailored to specific settings. We propose a…

统计方法学 · 统计学 2026-05-22 Yuyang Huo , Xiaoyang Wu , Changliang Zou , Haojie Ren

Consider testing multiple hypotheses using tests that can only be evaluated by simulation, such as permutation tests or bootstrap tests. This article introduces MMCTest, a sequential algorithm which gives, with arbitrarily high probability,…

统计方法学 · 统计学 2018-10-17 Axel Gandy , Georg Hahn

It is quite common in modern research, for a researcher to test many hypotheses. The statistical (frequentist) hypothesis testing framework, does not scale with the number of hypotheses in the sense that naively performing many hypothesis…

统计方法学 · 统计学 2013-06-26 Jonathan Rosenblatt

Conformal prediction has been a very popular method of distribution-free predictive inference in recent years in machine learning and statistics. Its popularity stems from the fact that it works as a wrapper around any prediction algorithm…

统计方法学 · 统计学 2021-06-07 Arun Kumar Kuchibhotla

Large language models (LLMs) are prone to generating factually incorrect outputs. Recent work has applied conformal prediction to provide uncertainty estimates and statistical guarantees for the factuality of LLM generations. However,…

计算与语言 · 计算机科学 2026-04-16 Aleksandr Rubashevskii , Dzianis Piatrashyn , Preslav Nakov , Maxim Panov

In multi-target tracking, a data association hypothesis assigns measurements to tracks, and the hypothesis likelihood (of the joint target-measurement associations) is used to compare among all hypotheses for truncation under a finite…

统计方法学 · 统计学 2021-08-10 Lingji Chen
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