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Alzheimer's disease (AD) is characterized by progressive microstructural deterioration in brain tissue, yet conventional imaging and histopathology often lack the sensitivity needed to detect subtle early-stage changes. Here, we present a…

医学物理 · 物理学 2025-12-09 Santanu Maity , Mousa Alrubayan , Mohammad Moshahid Khan , Prabhakar Pradhan

Anatomical brain parcellations dominate rs-fMRI-based Autism Spectrum Disorder (ASD) classification, yet their rigid boundaries may fail to capture the idiosyncratic connectivity patterns that characterise ASD. We present a graph-based deep…

计算机视觉与模式识别 · 计算机科学 2026-03-04 Syeda Hareem Madani , Noureen Bibi , Adam Rafiq Jeraj , Sumra Khan , Anas Zafar , Rizwan Qureshi

While Magnetic Resonance Imaging (MRI) has played an essential role in infant brain analysis, segmenting MRI into a number of tissues such as gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) is crucial and complex due to…

图像与视频处理 · 电气工程与系统科学 2021-12-28 Dinh-Hieu Hoang , Gia-Han Diep , Minh-Triet Tran , Ngan T. H Le

Two segmentation methods, one atlas-based and one neural-network-based, were compared to see how well they can each automatically segment the brain stem and cerebellum in Displacement Encoding with Stimulated Echoes Magnetic Resonance…

图像与视频处理 · 电气工程与系统科学 2021-09-30 Elle Buser , Emma Hart , Ben Huenemann

Interpreting machine learning model decisions is crucial for high-risk applications like healthcare. In digital pathology, large whole slide images (WSIs) are decomposed into smaller tiles and tile-derived features are processed by…

图像与视频处理 · 电气工程与系统科学 2024-07-03 Tomé Albuquerque , Anil Yüce , Markus D. Herrmann , Alvaro Gomariz

Alzheimer's disease and Frontotemporal dementia are two major types of dementia. Their accurate diagnosis and differentiation is crucial for determining specific intervention and treatment. However, differential diagnosis of these two types…

图像与视频处理 · 电气工程与系统科学 2022-06-16 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

This study investigates a 3D and fully convolutional neural network (CNN) for subcortical brain structure segmentation in MRI. 3D CNN architectures have been generally avoided due to their computational and memory requirements during…

计算机视觉与模式识别 · 计算机科学 2017-04-21 J. Dolz , C. Desrosiers , I. Ben Ayed

Machine learning is employed in healthcare to draw approximate conclusions regarding human diseases and mental health problems. Compared to older traditional methods, it can help to analyze data more efficiently and produce better and more…

神经元与认知 · 定量生物学 2023-05-25 Narges Ramesh , Yasmin Ghodsi , Hamidreza Bolhasani

Clinical neuroimaging data is naturally hierarchical. Different magnetic resonance imaging (MRI) sequences within a series, different slices covering the head, and different regions within each slice all confer different information. In…

图像与视频处理 · 电气工程与系统科学 2024-01-18 David A. Wood

Tissue classification is one of the significant tasks in the field of biomedical image analysis. Magnetic Resonance Imaging (MRI) is of great importance in tissue classification especially in the areas of brain tissue classification which…

计算机视觉与模式识别 · 计算机科学 2020-01-28 Shadman Sakib , Md. Abu Bakr Siddique

Objective(s): T$_2$* and susceptibility ($\chi$) MRI mapping provide complimentary measures of the haemodynamic environment in the placenta. The aims of this work were to use these simultaneously obtained measures to investigate the role of…

Multiple instance learning (MIL) has emerged as the dominant paradigm for whole slide image (WSI) analysis in computational pathology, achieving strong diagnostic performance through patch-level feature aggregation. However, existing MIL…

计算机视觉与模式识别 · 计算机科学 2025-11-17 Yiran Song , Yikai Zhang , Shuang Zhou , Guojun Xiong , Xiaofeng Yang , Nian Wang , Fenglong Ma , Rui Zhang , Mingquan Lin

Human brain anatomy and function display a combination of modular and hierarchical organization, suggesting the importance of both cohesive structures and variable resolutions in the facilitation of healthy cognitive processes. However,…

神经元与认知 · 定量生物学 2015-06-18 Christian Lohse , Danielle S. Bassett , Kelvin O. Lim , Jean M. Carlson

Characterizing in-utero brain development is essential for understanding typical and atypical neurodevelopment. Building on prior spatiotemporal fetal brain MRI atlases, we present the CRL-2025 fetal brain atlas, a spatiotemporal (4D) atlas…

Segmentation of sub-cortical structures from MRI scans is of interest in many neurological diagnosis. Since this is a laborious task machine learning and specifically deep learning (DL) methods have become explored. The structural…

图像与视频处理 · 电气工程与系统科学 2021-11-11 Jayanthi Sivaswamy , Alphin J Thottupattu , Mythri V , Raghav Mehta , R Sheelakumari , Chandrasekharan Kesavadas

Neuroimaging biomarkers that distinguish between typical brain aging and Alzheimer's disease (AD) are valuable for determining how much each contributes to cognitive decline. Machine learning models can derive multi-variate brain change…

The study of brain differences across Eastern and Western populations provides vital insights for understanding potential cultural and genetic influences on cognition and mental health. Diffusion MRI (dMRI) tractography is an important tool…

One fascinating aspect of the brain is its ability to process information in a fast and reliable manner. The functional architecture is thought to play a central role in this task, by encoding efficiently complex stimuli and facilitating…

神经元与认知 · 定量生物学 2016-02-17 Alberto Romagnoni , Jérôme Ribot , Daniel Bennequin , Jonathan D. Touboul

Alzheimer's disease (AD) diagnosis requires integrating neuroimaging with heterogeneous clinical evidence and reasoning under established criteria, yet most multimodal models remain opaque and weakly guideline-aligned. We present…

计算机视觉与模式识别 · 计算机科学 2026-03-26 Qiuhui Chen , Yushan Deng , Xuancheng Yao , Yi Hong

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

图像与视频处理 · 电气工程与系统科学 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer