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This study presents an innovative method for Alzheimer's disease diagnosis using 3D MRI designed to enhance the explainability of model decisions. Our approach adopts a soft attention mechanism, enabling 2D CNNs to extract volumetric…

图像与视频处理 · 电气工程与系统科学 2024-10-02 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano

Magnetic susceptibility imaging may provide valuable information about chemical composition and microstructural organization of tissue. However, its estimation from the MRI signal phase is particularly difficult as it is sensitive to…

We propose two methodologies in order to better understand the inter-individual variability of resting-state functional Magnetic Resonance Imaging (fMRI) brain data. The aim of the study was to quantify whether the average dendrogram is…

医学物理 · 物理学 2020-09-29 Loic Labache , Marc Joliot , Gaelle E. Doucet , Jerome Saracco

Structural magnetic resonance imaging (sMRI) provides accurate estimates of the brain's structural organization and learning invariant brain representations from sMRI is an enduring issue in neuroscience. Previous deep representation…

计算机视觉与模式识别 · 计算机科学 2023-06-21 Ning Jiang , Gongshu Wang , Tianyi Yan

Segmentation of very large images is a common problem in microscopy, medical imaging or remote sensing. The problem is usually addressed by sliding window inference, which can theoretically lead to seamlessly stitched predictions. However,…

计算机视觉与模式识别 · 计算机科学 2025-03-26 Elena Buglakova , Anwai Archit , Edoardo D'Imprima , Julia Mahamid , Constantin Pape , Anna Kreshuk

Magnetic resonance imaging (MRI) is a central modality for stroke imaging. It is used upon patient admission to make treatment decisions such as selecting patients for intravenous thrombolysis or endovascular therapy. MRI is later used in…

The aging society urgently requires scalable methods to monitor cognitive decline and identify social and psychological factors indicative of dementia risk in older adults. Our machine learning (ML) models captured facial, acoustic,…

We develop a hybrid model-based data-driven seizure detection algorithm called Mutual Information-based CNNAided Learned factor graphs (MICAL) for detection of eclectic seizures from EEG signals. Our proposed method contains three main…

信号处理 · 电气工程与系统科学 2023-01-17 Bahareh Salafian , Eyal Fishel Ben-Knaan , Nir Shlezinger , Sandrine de Ribaupierre , Nariman Farsad

Brain network provides important insights for the diagnosis of many brain disorders, and how to effectively model the brain structure has become one of the core issues in the domain of brain imaging analysis. Recently, various computational…

神经元与认知 · 定量生物学 2022-12-02 Zhengwang Xia , Tao Zhou , Saqib Mamoon , Amani Alfakih , Jianfeng Lu

We propose a system to visualize the chirality of the protein in brains, which would be helpful to diagnose early neurological degenerative diseases in vivo. These neurological degenerative diseases often occur along with some mark…

信号处理 · 电气工程与系统科学 2022-07-19 Wending Mai , Yifan Chen

Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is…

图像与视频处理 · 电气工程与系统科学 2023-09-12 Huy-Dung Nguyen , Michaël Clément , Vincent Planche , Boris Mansencal , Pierrick Coupé

The cerebral arteries are difficult to reproduce from first principles, featuring interwoven territories, and intricate layers of grey and white matter with differing metabolic demand. The aim of this study was to identify the ideal…

医学物理 · 物理学 2019-07-24 Jonathan Keelan , Emma M. L. Chung , James P. Hague

About 5-8% of individuals over the age of 60 have dementia. With our ever-aging population this number is likely to increase, making dementia one of the most important threats to public health in the 21st century. Given the phenotypic…

图像与视频处理 · 电气工程与系统科学 2021-02-16 Magnus Magnusson , Askell Love , Lotta M. Ellingsen

The human spine is a complex structure composed of 33 vertebrae. It holds the body and is important for leading a healthy life. The spine is vulnerable to age-related degenerations that can be identified through magnetic resonance imaging…

The application of information theory in medical imaging, particularly in magnetic resonance imaging (MRI), offers powerful quantitative tools for analyzing structural differences in brain tissues. This study utilizes mutual information…

医学物理 · 物理学 2025-05-13 Mazaher Kabiri , Shahd Qasem Mahd Tarman

Probabilistic atlas priors have been commonly used to derive adaptive and robust brain MRI segmentation algorithms. Widely-used neuroimage analysis pipelines rely heavily on these techniques, which are often computationally expensive. In…

计算机视觉与模式识别 · 计算机科学 2019-07-24 Adrian V. Dalca , Evan Yu , Polina Golland , Bruce Fischl , Mert R. Sabuncu , Juan Eugenio Iglesias

Diffusion Tensor Imaging (DTI) is an effective tool for the analysis of structural brain connectivity in normal development and in a broad range of brain disorders. However efforts to derive inherent characteristics of structural brain…

计算工程、金融与科学 · 计算机科学 2018-02-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

Accurate segmentation of MR brain tissue is a crucial step for diagnosis, surgical planning, and treatment of brain abnormalities. Automatic and reliable segmenta-tion methods are required to assist doctor. Over the last few years, deep…

计算机视觉与模式识别 · 计算机科学 2018-07-25 Yang Deng , Yao Sun , Yongpei Zhu , Shuo Zhang , Mingwang Zhu , Kehong Yuan

Alzheimer's disease (AD) is a complex neurodegenerative disorder that affects millions of people worldwide. Due to the heterogeneous nature of AD, its diagnosis and treatment pose critical challenges. Consequently, there is a growing…

Determining the brain perfusion is an important task for the diagnosis and treatment of vascular diseases such as occlusions and intracerebral haemorrhage. Even after successful diagnosis and treatment, there is a high risk of restenosis or…