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Motivation: Array Comparative Genomic Hybridization (aCGH) is used to scan the entire genome for variations in DNA copy number. A central task in the analysis of aCGH data is the segmentation into groups of probes sharing the same DNA copy…

定量方法 · 定量生物学 2008-04-29 Erez Ben-Yaacov , Yonina Eldar

The Quantum Approximate Optimization Algorithm (QAOA) is an algorithmic framework for finding approximate solutions to combinatorial optimization problems, derived from an approximation to the Quantum Adiabatic Algorithm (QAA). In solving…

量子物理 · 物理学 2020-02-05 Yue Ruan , Samuel Marsh , Xilin Xue , Xi Li , Zhihao Liu , Jingbo Wang

In this paper, we propose a new approach of network performance analysis, which is based on our previous works on the deterministic network analysis using the Gaussian approximation (DNA-GA). First, we extend our previous works to a…

信息论 · 计算机科学 2017-09-27 Ming Ding , David Lopez Perez , Guoqiang Mao , Zihuai Lin

DNA sequence alignment is important today as it is usually the first step in finding gene mutation, evolutionary similarities, protein structure, drug development and cancer treatment. Covid-19 is one recent example. There are many…

基因组学 · 定量生物学 2023-06-01 Suchindra , Preetam Nagaraj

The quantum approximate optimization algorithm (QAOA) has the potential to approximately solve complex combinatorial optimization problems in polynomial time. However, current noisy quantum devices cannot solve large problems due to…

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

定量方法 · 定量生物学 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

Functions of chemical composition are complex and discrete in nature making it impossible to optimize them with gradient methods. Genetic algorithms, which do not use derivative information, are used to maximize the thermal conductivity of…

材料科学 · 物理学 2018-01-30 Alexander Kerr , Kieran Mullen

The quantum approximate optimization algorithm (QAOA) has become a cornerstone of contemporary quantum applications development. Here we show that the \emph{density} of problem constraints versus problem variables acts as a performance…

量子物理 · 物理学 2021-08-31 V. Akshay , H. Philathong , I. Zacharov , J. Biamonte

Evolutionary algorithms rely very heavily on randomized behavior. Execution speed, therefore, depends strongly on how we implement randomness, such as our choice of pseudorandom number generator, or the algorithms used to map pseudorandom…

神经与进化计算 · 计算机科学 2024-12-04 Vincent A. Cicirello

The Quantum Approximate Optimization Algorithm (QAOA) has been one of the leading candidates for near-term quantum advantage in gate-model quantum computers. From its inception, this algorithm has sparked the desire for comparison between…

量子物理 · 物理学 2021-12-08 Colin Campbell , Edward Dahl

The quantum approximate optimization algorithm (QAOA) is a hybrid variational quantum-classical algorithm that solves combinatorial optimization problems. While there is evidence suggesting that the fixed form of the standard QAOA ansatz is…

Variational quantum algorithms (VQAs) have demonstrated considerable potential in solving NP-hard combinatorial problems in the contemporary near intermediate-scale quantum (NISQ) era. The quantum approximate optimisation algorithm (QAOA)…

量子物理 · 物理学 2024-05-09 Boy Choy , David J. Wales

In this paper, it is demonstrated that the DNA-based algorithm [Ho et al. 2005] for solving an instance of the clique problem to any a graph G = (V, E) with n vertices and p edges and its complementary graph G1 = (V, E1) with n vertices and…

数据结构与算法 · 计算机科学 2009-05-14 Weng-Long Chang , Ting-Ting Ren , Mang Feng , Jun Luo , Kawuu Weicheng Lin , Minyi Guo , Lai Chin Lu

We study the problem of probability distribution matching and sampling on near-term quantum computers, aiming to construct parameterized circuits that generate samples from a target distribution while minimizing resource overhead. This task…

量子物理 · 物理学 2026-05-26 Nicholas S. DiBrita , Jason Han , Krishna Bhatia , Younghyun Cho , Hengrui Luo , Tirthak Patel

A novel method based on pulse area analysis(PAA) was presented for acquisition nuclear spectrum by the digitizer. PAA method can be used as a substitute for the traditional method of pulse height analysis (PHA). In the PAA method a…

仪器与探测器 · 物理学 2014-07-24 Li Dongcang , Ren Zhongguo , Yang Lei , Qi Zhong , Meng Xiangting , Hu Bitao

Genetic algorithm (GA) is typically used to solve nonlinear model predictive control's optimization problem. However, the size of the search space in which the GA searches for the optimal control inputs is crucial for its applicability to…

最优化与控制 · 数学 2025-01-22 Eslam Mostafa , Hussein A. Aly , Ahmed Elliethy

Genetic algorithms are highly effective optimization techniques for many computationally challenging problems, including combinatorial optimization tasks like portfolio optimization. Quantum computing has also shown potential in addressing…

新兴技术 · 计算机科学 2025-04-28 Mohammad Kashfi Haghighi , Matthieu Fortin-Deschênes , Christophe Pere , Mickaël Camus

Challenges in natural sciences can often be phrased as optimization problems. Machine learning techniques have recently been applied to solve such problems. One example in chemistry is the design of tailor-made organic materials and…

神经与进化计算 · 计算机科学 2020-01-17 AkshatKumar Nigam , Pascal Friederich , Mario Krenn , Alán Aspuru-Guzik

Quantum computing is a promising technology to address combinatorial optimization problems, for example via the quantum approximate optimization algorithm (QAOA). Its potential, however, hinges on scaling toy problems to sizes relevant for…

Traditionally, we usually utilize the method of shotgun to cut a DNA sequence into pieces and we have to reconstruct the original DNA sequence from the pieces, those are widely used method for DNA assembly. Emerging DNA sequence…

分布式、并行与集群计算 · 计算机科学 2014-04-15 Yukun Zhong , ZhiWei He , XianHong Wang , XiongBin Cao