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Image-based computational fluid dynamics (CFD) has emerged as a powerful tool to study cardiovascular flows while 2D echocardiography (echo) is the most widely used non-invasive imaging modality for diagnosis of heart disease. Here, echo is…

Computer vision methods typically optimize for first-order dynamics (e.g., optical flow). However, in many cases the properties of interest are subtle variations in higher-order changes, such as acceleration. This is true in the cardiac…

图像与视频处理 · 电气工程与系统科学 2022-03-29 Brian L. Hill , Xin Liu , Daniel McDuff

Three-dimensional cardiovascular fluid dynamics simulations typically require computation of several cardiac cycles before they reach a periodic solution, rendering them computationally expensive. Furthermore, there is currently no…

计算工程、金融与科学 · 计算机科学 2021-06-28 Martin R. Pfaller , Jonathan Pham , Nathan M. Wilson , David W. Parker , Alison L. Marsden

Unnatural dynamics of the notorious vortex in the left ventricle is often associated with cardiac disease. Understanding how different cardiac diseases alter the flow physics in the left ventricle may therefore provide a powerful tool for…

医学物理 · 物理学 2019-03-18 Giuseppe Di Labbio , Lyes Kadem

Cardiopulmonary resuscitation (CPR) is one of the essential tools to ensure oxygen supply during cardiac arrest. However, the precise effects of chest compression are not quantifiable to this day. This often results in a low quality of…

Directional fluid flow in perivascular spaces surrounding cerebral arteries is hypothesized to play a key role in brain solute transport and clearance. While various drivers for pulsatile flow, such as cardiac or respiratory pulsations, are…

流体动力学 · 物理学 2023-10-05 Ingeborg G. Gjerde , Marie E. Rognes , Antonio L. Sanchez

Continuously measured arterial blood velocity can provide insight into physiological parameters and potential disease states. The efficient and effective description of the temporal profiles of arterial velocity is crucial for both clinical…

定量方法 · 定量生物学 2024-02-16 Justen R Geddes , Amanda Randles

Left ventricular assist devices (LVADs) are mechanical pumps, which can be used to support heart failure (HF) patients as bridge to transplant and destination therapy. To automatically adjust the LVAD speed, a physiological control system…

系统与控制 · 电气工程与系统科学 2021-05-04 Masoud Fetanat , Michael Stevens , Christopher Hayward , Nigel H. Lovell

Although atrial fibrillation (AF), a common arrhythmia, frequently presents in patients with underlying valvular disease, its hemodynamic contributions are not fully understood. The present work aimed to computationally study how physical…

流体动力学 · 物理学 2016-07-27 Stefania Scarsoglio , Andrea Saglietto , Fiorenzo Gaita , Luca Ridolfi , Matteo Anselmino

Understanding the formation, propagation, and breakdown of the main vortex ring (VR) is essential for characterizing left ventricular (LV) hemodynamics, as its dynamics have been linked to the onset and progression of cardiovascular…

流体动力学 · 物理学 2025-07-30 Eneko Lazpita , Michael Neidlin , Jesus Garicano-Mena , Soledad Le Clainche

Percutaneous catheter pumps are intraventricular temporary mechanical circulatory support (MCS) devices that are positioned across the aortic valve into the left ventricle (LV) and provide continuous antegrade blood flow from the LV into…

医学物理 · 物理学 2023-12-11 Greg W. Burgreen , Mansur Zhussupbekov , Rodrigo Méndez Rojano , James F. Antaki

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

机器学习 · 计算机科学 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

Methods: A method of the pulsation for a pVAD is proposed (AP-pVAD Model). AP-pVAD Model consists of two parts: NPQ Model and LSTM-Transformer Model. (1)The NPQ Model determines the mathematical relationship between motor speed, pressure,…

医学物理 · 物理学 2025-03-11 Chaoran E , Chenghan Chen , Yuyang Shi , Haiyun Wang , Peixin Hua , Xiwen Zhang

Understanding the interaction between the valves and walls of the heart is important in assessing and subsequently treating heart dysfunction. With advancements in cardiac imaging, nonlinear mechanics and computational techniques, it is now…

医学物理 · 物理学 2017-04-07 Hao Gao , Liuyang Feng , Nan Qi , Colin Berry , Boyce Griffith , Xiaoyu Luo

Usually, clinicians assess the correct hemodynamic behavior and fetal well-being during the gestational age thanks to their professional expertise, with the support of some indices defined for Doppler fetal waveforms. Although this approach…

The impact of increased stiffness and pulsatile load on the circulation and their influence on heart performance have been documented not only for cardiovascular events but also for ventricular dysfunctions. For this reason, computer models…

A minimal model for mechanical motion of the left ventricle is proposed. The model assumes the left ventricle to be a harmonic oscillator with two distinct phases, simulating the systolic and diastolic phases, at which both the amplitude…

医学物理 · 物理学 2007-05-23 S. Dubi , C. Dubi , Y. Dubi

Computational fluid dynamics (CFD) models of blood flow in the left ventricle (LV) and aorta are important tools for analyzing the mechanistic links between myocardial deformation and flow patterns. Typically, the use of image-based…

There are more than 300,000 heart valves implanted annually worldwide with about 50% of them being mechanical valves. The heart valve replacement is often a common treatment for severe valvular disease. However, valves may dysfunction…

流体动力学 · 物理学 2018-03-12 Fardin Khalili , Peshala T. Gamage , Hansen Mansy

Valvular heart diseases are growing concern in impoverished parts of the world, such as Southern-Africa, claiming more than 31 % of total deaths related to cardiovascular diseases. The ability to model the effects of regurgitant and…

医学物理 · 物理学 2022-04-11 Ryno Laubscher , Jacques Liebenberg , Philip Herbst