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The spread of COVID-19 has been greatly impacted by regulatory policies and behavior patterns that vary across counties, states, and countries. Population-level dynamics of COVID-19 can generally be described using a set of ordinary…

应用统计 · 统计学 2022-04-11 Joshua P. Keller , Tianjian Zhou , Andee Kaplan , G. Brooke Anderson , Wen Zhou

Over the course of the COVID-19 pandemic, Generalised Additive Models (GAMs) have been successfully employed on numerous occasions to obtain vital data-driven insights. In this paper we further substantiate the success story of GAMs,…

We introduce a minimalist outbreak forecasting model that combines data-driven parameter estimation with variational data assimilation. By focusing on the fundamental components of nonlinear disease transmission and representing data in a…

种群与进化 · 定量生物学 2021-10-12 Hannah R. Biegel , Joceline Lega

This paper deals with the problem of estimating variables in nonlinear models for the spread of disease and its application to the COVID-19 epidemic. First unconstrained methods are revisited and they are shown to correspond to the…

最优化与控制 · 数学 2020-08-20 Mauricio C. de Oliveira

Compartmental models are widely adopted to describe and predict the spreading of infectious diseases. The unknown parameters of such models need to be estimated from the data. Furthermore, when some of the model variables are not…

物理与社会 · 物理学 2021-01-18 Luca Gallo , Mattia Frasca , Vito Latora , Giovanni Russo

Mathematical models in epidemiology are an indispensable tool to determine the dynamics and important characteristics of infectious diseases. Apart from their scientific merit, these models are often used to inform political decisions and…

The COVID-19 pandemic has brought forth the importance of epidemic forecasting for decision makers in multiple domains, ranging from public health to the economy as a whole. While forecasting epidemic progression is frequently…

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic affecting over 200 countries and regions. Inference about the transmission dynamics of COVID-19 can provide important insights into the speed of disease spread and…

统计方法学 · 统计学 2020-07-06 Tianjian Zhou , Yuan Ji

Comparing how different populations have suffered under COVID-19 is a core part of ongoing investigations into how public policy and social inequalities influence the number of and severity of COVID-19 cases. But COVID-19 incidence can vary…

种群与进化 · 定量生物学 2022-11-17 Ryan Wilkinson , Marcus Roper

This paper investigates various ways in which a pandemic such as the novel coronavirus, could be predicted using different mathematical models. It also studies the various ways in which these models could be depicted using various…

综合经济学 · 经济学 2021-02-16 Shailesh Bharati , Rahul Batra

The COVID-19 pandemic prompted a surge in computational models to simulate disease dynamics and guide interventions. Agent-based models (ABMs) are well-suited to capture population and environmental heterogeneity, but their rapid deployment…

In the wake of the 2020 COVID-19 epidemic, much work has been performed on the development of mathematical models for the simulation of the epidemic, and of disease models generally. Most works follow the susceptible-infected-removed (SIR)…

数值分析 · 数学 2022-05-18 Nicola Guglielmi , Elisa Iacomini , Alex Viguerie

Modern Bayesian approaches and workflows emphasize in how simulation is important in the context of model developing. Simulation can help researchers understand how the model behaves in a controlled setting and can be used to stress the…

Scientific advice to the UK government throughout the COVID-19 pandemic has been informed by ensembles of epidemiological models provided by members of the Scientific Pandemic Influenza group on Modelling (SPI-M). Among other applications,…

应用统计 · 统计学 2021-08-13 D. S. Silk , V. E. Bowman , D. Semochkina , U. Dalrymple , D. C. Woods

The growing literature on the propagation of COVID-19 relies on various dynamic SIR-type models (Susceptible-Infected-Recovered) which yield model-dependent results. For transparency and ease of comparing the results, we introduce a common…

种群与进化 · 定量生物学 2020-06-19 Christian Gourieroux , Joann Jasiak

In this article, we consider a dynamic epidemiology model for the spread of the COVID-19 infection. Starting from the classical SEIR model, the model is modified so as to better describe characteristic features of the underlying pathogen…

种群与进化 · 定量生物学 2020-05-22 Daniela Calvetti , Alexander Hoover , Johnie Rose , Erkki Somersalo

We present a unifying, tractable approach for studying the spread of viruses causing complex diseases requiring to be modeled using a large number of types (e.g., infective stage, clinical state, risk factor class). We show that recording…

The Covid-19 outbreak of 2020 has required many governments to develop mathematical-statistical models of the outbreak for policy and planning purposes. This work provides a tutorial on building a compartmental model using Susceptibles,…

应用统计 · 统计学 2020-05-27 Ryad Ghanam , Edward L. Boone , Abdel-Salam G. Abdel-Salam

In this research, we study the propagation patterns of epidemic diseases such as the COVID-19 coronavirus, from a mathematical modeling perspective. The study is based on an extensions of the well-known susceptible-infected-recovered (SIR)…

种群与进化 · 定量生物学 2021-01-01 Reza Sameni