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Biological systems excel at building spatial structures on scales ranging from nanometers to kilometers and exhibit temporal patterning from milliseconds to years. One approach that nature has taken to accomplish this relies on the…

细胞行为 · 定量生物学 2009-11-10 Herbert Levine , Eshel Ben-Jacob

Bacterial colonies composed of elongated cells form active nematic fluids that spontaneously self-organise into ordered domains of aligned cells and exhibit self-generated chaotic flows powered by cell growth. While their dynamics have…

The mechanism of bacterial cell size control has been a mystery for decades, which involves the well-coordinated growth and division in the cell cycle. The revolutionary modern techniques of microfluidics and the advanced live imaging…

统计力学 · 物理学 2021-08-30 Liang Luo , Yang Bai , Xiongfei Fu

Biological systems are promising substrates for computation because they naturally process environmental information through complex internal dynamics. In this study, we investigate whether bacterial metabolic models can act as physical…

新兴技术 · 计算机科学 2026-04-23 Laura Alonso Bartolomé , Jean-Loup Faulon , Xavier Hinaut

The population growth of a Staphylococcus aureus culture was followed by rheological measurements, under steady-state and dynamic shear flows. We observed a rich viscoelastic behaviour as a consequence of the bacteria activity. First, the…

软凝聚态物质 · 物理学 2012-09-25 R. Portela , P. L. Almeida , P. Patricio , T. Cidade , R. G. Sobral , C. R. Leal

The striking variety of macroscopic morphologies displayed by bacterial colonies depends on microscopic environmental and behavioural details in a manner that is currently not well understood. A surprising example is sibling inhibition,…

细胞行为 · 定量生物学 2026-05-15 Dario Buonomo , Francesco Imperi , Fabio Bruni , Marco Polin , Barbara Capone

Proliferating cell collectives often develop an active growth layer near their boundary that regulates expansion and morphology, as observed in systems ranging from bacterial biofilms to epithelial tissues and tumor spheroids. While such…

软凝聚态物质 · 物理学 2026-04-27 Fidel Álvarez-Murphy , Ignacio Medina , Néstor Sepúlveda , Gustavo Düring

Biomolecular condensates self-assemble when proteins and nucleic acids spontaneously demix to form droplets within the crowded intracellular milieu. This simple mechanism underlies the formation of a wide variety of membraneless…

统计力学 · 物理学 2021-06-30 William M. Jacobs

Colonies of the social bacterium Myxococcus xanthus go through a morphological transition from a thin colony of cells to three-dimensional droplet-like fruiting bodies as a strategy to survive starvation. The biological pathways that…

Many chemotactic bacteria inhabit environments in which chemicals appear as localized pulses and evolve by processes such as diffusion and mixing. We show that, in such environments, physical limits on the accuracy of temporal gradient…

生物物理 · 物理学 2016-01-19 Andrew M. Hein , Douglas R. Brumley , Francesco Carrara , Roman Stocker , Simon A. Levin

Bacteria invade surfaces by forming dense colonies encased in a polymer matrix. Successful settlement of founder bacteria, early microcolony development and later macroscopic spreading of these biofilms on surfaces rely on complex physical…

软凝聚态物质 · 物理学 2025-08-27 Anthony Pietz , Karin John , Uwe Thiele

Drying of bacterial suspensions is frequently encountered in a plethora of natural and engineering processes. However, the evaporation-driven mechanical instabilities of dense consolidating bacterial suspensions have not been explored…

软凝聚态物质 · 物理学 2022-07-26 Xiaolei Ma , Zhengyang Liu , Wei Zeng , Tianyi Lin , Xin Tian , Xiang Cheng

Monolayers of growing non-motile rod-shaped bacteria act as active nematic materials composed of hard particles rather than the flexible components of other commonly studied active nematics. The organization of these granular monolayers has…

软凝聚态物质 · 物理学 2023-05-12 Blake Langeslay , Gabriel Juarez

Many biological materials must couple mechanical strength with the ability to rapidly self-assemble at a specific location. In particular, biomolecular condensates readily self-assemble via phase separation, but may also need to resist…

Heterogeneous systems of active matter exhibit a range of complex emergent dynamical patterns. In particular, it is difficult to predict the properties of the mixed system based on its constituents. These considerations are particularly…

软凝聚态物质 · 物理学 2021-04-07 Shlomit Peled , Shawn D. Ryan , Sebastian Heidenreich , Markus Bar , Gil Ariel , Avraham Be'er

We study the effect of discreteness on various models for patterning in bacterial colonies. In a bacterial colony with branching pattern, there are discrete entities - bacteria - which are only two orders of magnitude smaller than the…

无序系统与神经网络 · 物理学 2007-05-23 Inon Cohen , Ido Golding , Yonathan Kozlovsky , Eshel Ben-Jacob

Understanding how growth induces form is a longstanding biological question. Many studies concentrated on the shapes of plant cells, fungi or bacteria. Some others have shown the importance of the mechanical properties of bacterial walls…

生物物理 · 物理学 2007-05-23 Arezki Boudaoud

The colonisation of a soft passive material by motile cells such as bacteria is common in biology. The resulting colonies of the invading cells are often observed to exhibit intricate patterns whose morphology and dynamics can depend on a…

软凝聚态物质 · 物理学 2021-01-12 Mohammad Imaran , Mandar Inamdar , Ranganathan Prabhakar , Raghunath Chelakkot

Bacteria are easily characterizable model organisms with an impressively complicated set of capabilities. Among their capabilities is quorum sensing, a detailed cell-cell signaling system that may have a common origin with eukaryotic…

神经元与认知 · 定量生物学 2017-09-14 Archana Ram , Andrew Lo

We present a model for unicellular algal growth as motivated by several experiments implicating the importance of calcium ions and ``loosening'' enzymes in morphogenesis. A growing cell at rest in a diffusive calcium solution is viewed as…

patt-sol · 物理学 2009-10-30 Royce Kam , Herbert Levine