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Whole Slide Imaging (WSI) is a cornerstone of digital pathology, offering detailed insights critical for diagnosis and research. Yet, the gigapixel size of WSIs imposes significant computational challenges, limiting their practical utility.…

图像与视频处理 · 电气工程与系统科学 2024-11-15 Ravi Kant Gupta , Shounak Das , Amit Sethi

Whole Slide Images (WSIs) play a crucial role in accurate cancer diagnosis and prognosis, as they provide tissue details at the cellular level. However, the rapid growth of computational tasks involving WSIs poses significant challenges.…

计算机视觉与模式识别 · 计算机科学 2025-10-30 Doanh C. Bui , Hoai Luan Pham , Vu Trung Duong Le , Tuan Hai Vu , Van Duy Tran , Khang Nguyen , Yasuhiko Nakashima

The advancement of digital pathology, particularly through computational analysis of whole slide images (WSI), is poised to significantly enhance diagnostic precision and efficiency. However, the large size and complexity of WSIs make it…

计算机视觉与模式识别 · 计算机科学 2024-11-14 Ravi Kant Gupta , Dadi Dharani , Shambhavi Shanker , Amit Sethi

The difficulty of processing gigapixel whole slide images (WSIs) in clinical microscopy has been a long-standing barrier to implementing computer aided diagnostic systems. Since modern computing resources are unable to perform computations…

计算机视觉与模式识别 · 计算机科学 2020-08-13 Sam Maksoud , Kun Zhao , Peter Hobson , Anthony Jennings , Brian Lovell

Computational methods on analyzing Whole Slide Images (WSIs) enable early diagnosis and treatments by supporting pathologists in detection and classification of tumors. However, the extremely high resolution of WSIs makes end-to-end…

计算机视觉与模式识别 · 计算机科学 2026-03-18 Umar Marikkar , Muhammad Awais , Sara Atito

Whole-slide images (WSIs) are fundamental for computational pathology, where accurate lesion segmentation is critical for clinical decision making. Existing methods partition WSIs into discrete patches, disrupting spatial continuity and…

计算机视觉与模式识别 · 计算机科学 2026-03-05 Yunheng Wu , Wenqi Huang , Liangyi Wang , Masahiro Oda , Yuichiro Hayashi , Daniel Rueckert , Kensaku Mori

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

计算机视觉与模式识别 · 计算机科学 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Whole slide images (WSIs) in computational pathology (CPath) pose a major computational challenge due to their gigapixel scale, often requiring the processing of tens to hundreds of thousands of high-resolution patches per slide. This…

计算机视觉与模式识别 · 计算机科学 2025-08-21 Yonghan Shin , SeungKyu Kim , Won-Ki Jeong

Whole slide imaging is fundamental to biomedical microscopy and computational pathology. Previously, learning representations for gigapixel-sized whole slide images (WSIs) has relied on multiple instance learning with weak labels, which do…

计算机视觉与模式识别 · 计算机科学 2024-05-27 Xinhai Hou , Cheng Jiang , Akhil Kondepudi , Yiwei Lyu , Asadur Chowdury , Honglak Lee , Todd C. Hollon

Multiple instance learning (MIL) has become a preferred method for gigapixel whole slide image (WSI) classification without requiring patch-level annotations. Current MIL research primarily relies on embedding-based approaches, which…

计算机视觉与模式识别 · 计算机科学 2025-03-10 Bryan Wong , Sungrae Hong , Mun Yong Yi

Computer-aided pathology diagnosis based on the classification of Whole Slide Image (WSI) plays an important role in clinical practice, and it is often formulated as a weakly-supervised Multiple Instance Learning (MIL) problem. Existing…

计算机视觉与模式识别 · 计算机科学 2022-10-11 Linhao Qu , Xiaoyuan Luo , Manning Wang , Zhijian Song

Despite remarkable efforts been made, the classification of gigapixels whole-slide image (WSI) is severely restrained from either the constrained computing resources for the whole slides, or limited utilizing of the knowledge from different…

计算机视觉与模式识别 · 计算机科学 2022-07-13 Ming Feng , Kele Xu , Nanhui Wu , Weiquan Huang , Yan Bai , Changjian Wang , Huaimin Wang

Whole slide imaging (WSI) refers to the digitization of a tissue specimen which enables pathologists to explore high-resolution images on a monitor rather than through a microscope. The formation of tissue folds occur during tissue…

图像与视频处理 · 电气工程与系统科学 2019-03-19 Morteza Babaie , H. R. Tizhoosh

A crucial step to efficiently integrate Whole Slide Images (WSIs) in computational pathology is assigning a single high-quality feature vector, i.e., one embedding, to each WSI. With the existence of many pre-trained deep neural networks…

图像与视频处理 · 电气工程与系统科学 2025-05-22 Sobhan Hemati , Ghazal Alabtah , Saghir Alfasly , H. R. Tizhoosh

Deep learning methods such as convolutional neural networks (CNNs) are difficult to directly utilize to analyze whole slide images (WSIs) due to the large image dimensions. We overcome this limitation by proposing a novel two-stage…

图像与视频处理 · 电气工程与系统科学 2021-06-15 Shivam Kalra , Mohammed Adnan , Sobhan Hemati , Taher Dehkharghanian , Shahryar Rahnamayan , Hamid Tizhoosh

A Whole Slide Image (WSI) is a high-resolution digital image created by scanning an entire glass slide containing a biological specimen, such as tissue sections or cell samples, at multiple magnifications. These images are digitally…

Whole slide images (WSIs) are high-resolution, gigapixel sized images that pose significant computational challenges for traditional machine learning models due to their size and heterogeneity.In this paper, we present a scalable and…

计算机视觉与模式识别 · 计算机科学 2025-01-22 Ravi Kant Gupta , Shounak Das , Ardhendu Sekhar , Amit Sethi

We present a novel diffusion-based approach to generate synthetic histopathological Whole Slide Images (WSIs) at an unprecedented gigapixel scale. Synthetic WSIs have many potential applications: They can augment training datasets to…

图像与视频处理 · 电气工程与系统科学 2023-11-15 Robert Harb , Thomas Pock , Heimo Müller

Whole Slide Imaging (WSI) has become an important topic during the last decade. Even though significant progress in both medical image processing and computational resources has been achieved, there are still problems in WSI that need to be…

图像与视频处理 · 电气工程与系统科学 2019-03-19 Wafa Chenni , Habib Herbi , Morteza Babaie , H. R. Tizhoosh

Recently there have been many algorithms proposed for the classification of very high resolution whole slide images (WSIs). These new algorithms are mostly focused on finding novel ways to combine the information from small local patches…

计算机视觉与模式识别 · 计算机科学 2023-10-06 Long Nguyen , Aiden Nibali , Joshua Millward , Zhen He
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