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Dementia, a progressive neurodegenerative disorder, affects memory, reasoning, and daily functioning, creating challenges for individuals and healthcare systems. Early detection is crucial for timely interventions that may slow disease…

神经元与认知 · 定量生物学 2025-03-04 Sahar Sinene Mehdoui , Abdelhamid Bouzid , Daniel Sierra-Sosa , Adel Elmaghraby

In this work we explore how language models can be employed to analyze language and discriminate between mentally impaired and healthy subjects through the perplexity metric. Perplexity was originally conceived as an information-theoretic…

计算与语言 · 计算机科学 2023-02-03 Davide Colla , Matteo Delsanto , Marco Agosto , Benedetto Vitiello , Daniele Paolo Radicioni

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease affecting 50 million people worldwide. Low-cost, accurate identification of key markers of AD is crucial for timely diagnosis and intervention. Language impairment is one…

计算与语言 · 计算机科学 2025-05-27 Tingyu Mo , Jacqueline C. K. Lam , Victor O. K. Li , Lawrence Y. L. Cheung

Dementia is a neuropsychiatric brain disorder that usually occurs when one or more brain cells stop working partially or at all. Diagnosis of this disorder in the early phases of the disease is a vital task to rescue patients lives from bad…

机器学习 · 计算机科学 2022-09-13 Sinan Faouri , Mahmood AlBashayreh , Mohammad Azzeh

Recent progress has been made in detecting early stage dementia entirely through recordings of patient speech. Multimodal speech analysis methods were applied to the PROCESS challenge, which requires participants to use audio recordings of…

音频与语音处理 · 电气工程与系统科学 2025-02-14 Lei Chi , Arav Sharma , Ari Gebhardt , Joseph T. Colonel

Dementia is a neurodegenerative disease that causes gradual cognitive impairment, which is very common in the world and undergoes a lot of research every year to prevent and cure it. It severely impacts the patient's ability to remember…

In recent years there has been a burgeoning interest in the use of computational methods to distinguish between elicited speech samples produced by patients with dementia, and those from healthy controls. The difference between perplexity…

计算与语言 · 计算机科学 2020-06-30 Trevor Cohen , Serguei Pakhomov

Background: Subtle changes in spontaneous language production are among the earliest indicators of cognitive decline. Identifying linguistically interpretable markers of dementia can support transparent and clinically grounded screening…

计算与语言 · 计算机科学 2026-02-12 Artsvik Avetisyan , Sachin Kumar

Introduction: We present a screening method for early dementia using features based on sound objects as voice biomarkers. Methods: The final dataset used for machine learning models consisted of 266 observations, with a distribution of 186…

The use of spontaneous language to derive appropriate digital markers has become an emergent, promising and non-intrusive method to diagnose and monitor dementia. Here we propose methods to capture language coherence as a cost-effective,…

计算与语言 · 计算机科学 2023-10-17 Dimitris Gkoumas , Adam Tsakalidis , Maria Liakata

We present an approach to automatic detection of Alzheimer's type dementia based on characteristics of spontaneous spoken language dialogue consisting of interviews recorded in natural settings. The proposed method employs additive logistic…

音频与语音处理 · 电气工程与系统科学 2018-11-27 Saturnino Luz , Sofia de la Fuente , Pierre Albert

Automatic detection of Alzheimer's dementia by speech processing is enhanced when features of both the acoustic waveform and the content are extracted. Audio and text transcription have been widely used in health-related tasks, as spectral…

音频与语音处理 · 电气工程与系统科学 2020-08-12 Edward L. Campbell , Laura Docío-Fernández , Javier Jiménez Raboso , Carmen García-Mateo

Alzheimer's disease (AD) constitutes a complex neurocognitive disease and is the main cause of dementia. Although many studies have been proposed targeting at diagnosing dementia through spontaneous speech, there are still limitations.…

计算与语言 · 计算机科学 2023-08-24 Loukas Ilias , Dimitris Askounis

The global prevalence of dementia is projected to double by 2050, highlighting the urgent need for scalable diagnostic tools. This study utilizes digital cognitive tasks with eye-tracking data correlated with memory processes to distinguish…

人机交互 · 计算机科学 2025-08-28 Tomás Silva Santos Rocha , Anastasiia Mikhailova , Moreno I. Coco , José Santos-Victor

Dementia is a neurological syndrome marked by cognitive decline. Alzheimer's disease (AD) and Frontotemporal dementia (FTD) are the common forms of dementia, each with distinct progression patterns. EEG, a non-invasive tool for recording…

信号处理 · 电气工程与系统科学 2024-08-21 Shivani Ranjan , Ayush Tripathi , Harshal Shende , Robin Badal , Amit Kumar , Pramod Yadav , Deepak Joshi , Lalan Kumar

Deep transformer models have been used to detect linguistic anomalies in patient transcripts for early Alzheimer's disease (AD) screening. While pre-trained neural language models (LMs) fine-tuned on AD transcripts perform well, little…

计算与语言 · 计算机科学 2025-06-09 Zhecheng Sheng , Xiruo Ding , Brian Hur , Changye Li , Trevor Cohen , Serguei Pakhomov

The close link between cognitive decline and language has fostered long-standing collaboration between the NLP and medical communities in dementia research. To examine this, we reviewed over 240 papers applying NLP to dementia-related…

计算与语言 · 计算机科学 2025-02-11 Lotem Peled-Cohen , Roi Reichart

Based on official estimates, 50 million people worldwide are affected by dementia, and this number increases by 10 million new patients every year. Without a cure, clinical prognostication and early intervention represent the most effective…

计算与语言 · 计算机科学 2024-09-06 Francisco de Arriba-Pérez , Silvia García-Méndez

One of the most prevalent symptoms among the elderly population, dementia, can be detected by classifiers trained on linguistic features extracted from narrative transcripts. However, these linguistic features are impacted in a similar but…

机器学习 · 计算机科学 2019-09-10 Zining Zhu , Jekaterina Novikova , Frank Rudzicz

In this paper, we exploit a Fully Convolutional Network (FCN) to analyze the audio data of spontaneous speech for dementia detection. A fully convolutional network accommodates speech samples with varying lengths, thus enabling us to…

音频与语音处理 · 电气工程与系统科学 2020-08-18 Youxiang Zhu , Xiaohui Liang