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We study the use of the Euler characteristic for multiparameter topological data analysis. Euler characteristic is a classical, well-understood topological invariant that has appeared in numerous applications, including in the context of…

This article pursues a statistical study of the Hough transform, the celebrated computer vision algorithm used to detect the presence of lines in a noisy image. We first study asymptotic properties of the Hough transform estimator, whose…

统计理论 · 数学 2007-06-13 Alexander Goldenshluger , Assaf Zeevi

We propose a model-agnostic, progressive test-time energy adaptation approach for medical image segmentation. Maintaining model performance across diverse medical datasets is challenging, as distribution shifts arise from inconsistent…

计算机视觉与模式识别 · 计算机科学 2025-03-24 Xiaoran Zhang , Byung-Woo Hong , Hyoungseob Park , Daniel H. Pak , Anne-Marie Rickmann , Lawrence H. Staib , James S. Duncan , Alex Wong

We discuss a general approach to handling "multiple hypotheses" testing in the case when a particular hypothesis states that the vector of parameters identifying the distribution of observations belongs to a convex compact set associated…

统计理论 · 数学 2016-02-24 A. Goldenshluger , A. Juditski , A. Nemirovski

In the medical field, accurate diagnosis of lung cancer is crucial for treatment. Traditional manual analysis methods have significant limitations in terms of accuracy and efficiency. To address this issue, this paper proposes a deep…

图像与视频处理 · 电气工程与系统科学 2025-01-10 Ziyang Gao , Yong Tian , Shih-Chi Lin , Junghua Lin

Risk stratification (characterization) of tumors from radiology images can be more accurate and faster with computer-aided diagnosis (CAD) tools. Tumor characterization through such tools can also enable non-invasive cancer staging,…

计算机视觉与模式识别 · 计算机科学 2019-01-21 Sarfaraz Hussein , Pujan Kandel , Candice W. Bolan , Michael B. Wallace , Ulas Bagci

Assessing cancer progression in liver CT scans is a clinical challenge, requiring a comparison of scans at different times for the same patient. Practitioners must identify existing tumors, compare them with prior exams, identify new…

图像与视频处理 · 电气工程与系统科学 2025-01-27 Walid Yassine , Martin Charachon , Céline Hudelot , Roberto Ardon

Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a…

计算机视觉与模式识别 · 计算机科学 2018-10-18 Sarfaraz Hussein , Robert Gillies , Kunlin Cao , Qi Song , Ulas Bagci

With the routine collection of massive-dimensional predictors in many application areas, screening methods that rapidly identify a small subset of promising predictors have become commonplace. We propose a new MOdular Bayes Screening (MOBS)…

统计方法学 · 统计学 2017-03-30 Yuhan Chen , David B. Dunson

The accurate classification of lymphoma subtypes using hematoxylin and eosin (H&E)-stained tissue is complicated by the wide range of morphological features these cancers can exhibit. We present LymphoML - an interpretable machine learning…

A major challenge for cancer pathologists is to determine whether a new tumor in a patient with cancer is a metastasis or an independent occurrence of the disease. In recent years numerous studies have evaluated pairs of tumor specimens to…

应用统计 · 统计学 2015-11-18 Irina Ostrovnaya , Venkatraman E. Seshan , Colin B. Begg

Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…

图像与视频处理 · 电气工程与系统科学 2022-02-28 Hanxiao Zhang , Liang Chen , Xiao Gu , Minghui Zhang , Yulei Qin , Feng Yao , Zhexin Wang , Yun Gu , Guang-Zhong Yang

This work studies lung tumor growth prediction from sparse and irregular longitudinal computed tomography (CT) observations with measurement variability. A Bayesian physics-informed neural network is developed by combining Gompertz growth…

机器学习 · 计算机科学 2026-05-14 Lingfei Kong , Haoran Ma

Deep learning-based medical image segmentation techniques have shown promising results when evaluated based on conventional metrics such as the Dice score or Intersection-over-Union. However, these fully automatic methods often fail to meet…

图像与视频处理 · 电气工程与系统科学 2025-08-06 Liu Li , Qiang Ma , Cheng Ouyang , Johannes C. Paetzold , Daniel Rueckert , Bernhard Kainz

In recent years, machine learning has witnessed extensive adoption across various sectors, yet its application in medical image-based disease detection and diagnosis remains challenging due to distribution shifts in real-world data. In…

机器学习 · 计算机科学 2024-02-13 Masoumeh Javanbakhat , Md Tasnimul Hasan , Cristoph Lippert

Lung cancer is highly lethal, emphasizing the critical need for early detection. However, identifying lung nodules poses significant challenges for radiologists, who rely heavily on their expertise for accurate diagnosis. To address this…

图像与视频处理 · 电气工程与系统科学 2023-10-17 Hossein Jafari , Karim Faez , Hamidreza Amindavar

The paper concerns a new statistical method for assessing dissimilarity of two random sets based on one realisation of each of them. The method focuses on shapes of the components of the random sets, namely on the curvature of their…

We present Euler Characteristic Surfaces as a multiscale spatiotemporal topological summary of time series data encapsulating the topology of the system at different time instants and length scales. Euler Characteristic Surfaces with an…

其他凝聚态物理 · 物理学 2024-08-20 Anamika Roy , Atish J. Mitra , Tapati Dutta

The focus of modern biomedical studies has gradually shifted to explanation and estimation of joint effects of high dimensional predictors on disease risks. Quantifying uncertainty in these estimates may provide valuable insight into…

统计方法学 · 统计学 2021-03-09 Zhe Fei , Yi Li

We propose a test for model specification of a parametric diffusion process based on a kernel estimation of the transitional density of the process. The empirical likelihood is used to formulate a statistic, for each kernel smoothing…

统计理论 · 数学 2009-09-29 Song Xi Chen , Jiti Gao , Cheng Yong Tang