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Automatic prediction of amyotrophic lateral sclerosis (ALS) disease progression provides a more efficient and objective alternative than manual approaches. We propose ALS longitudinal speech transformer (ALST), a neural network-based…

Amyotrophic Lateral Sclerosis (ALS) is a complex neurodegenerative disorder involving motor neuron degeneration. Significant research has begun to establish brain magnetic resonance imaging (MRI) as a potential biomarker to diagnose and…

Amyotrophic Lateral Sclerosis (ALS) constitutes a progressive neurodegenerative disease with varying symptoms, including decline in speech intelligibility. Existing studies, which recognize dysarthria in ALS patients by predicting the…

机器学习 · 计算机科学 2025-03-05 Loukas Ilias , Dimitris Askounis

We propose a cloud-based multimodal dialog platform for the remote assessment and monitoring of Amyotrophic Lateral Sclerosis (ALS) at scale. This paper presents our vision, technology setup, and an initial investigation of the efficacy of…

Amyotrophic lateral sclerosis (ALS) is a severe disease with a typical survival of 3-5 years after symptom onset. Current treatments offer only limited life extension, and the variability in patient responses highlights the need for…

机器学习 · 计算机科学 2025-11-05 Guillaume Tejedor , Veronika Peralta , Nicolas Labroche , Patrick Marcel , Hélène Blasco , Hugo Alarcan

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by a rapid motor decline, leading to respiratory failure and subsequently to death. In this context, researchers have sought for models to automatically…

机器学习 · 计算机科学 2019-07-31 Telma Pereira , Sofia Pires , Marta Gromicho , Susana Pinto , Mamede de Carvalho , Sara C. Madeira

Amyotrophic Lateral Sclerosis (ALS) and Myopathy present considerable challenges in the realm of neuromuscular disorder diagnostics. In this study, we employ advanced deep-learning techniques to address the detection of ALS and Myopathy,…

信号处理 · 电气工程与系统科学 2024-10-30 Md. Toufiqur Rahman , Minhajur Rahman , Celia Shahnaz

Amyotrophic lateral sclerosis is a fatal disease that not only affects movement, speech, and breath but also cognition. Recent studies have focused on the use of language analysis techniques to detect ALS and infer scales for monitoring…

计算与语言 · 计算机科学 2023-09-14 Carla Agurto , Guillermo Cecchi , Bo Wen , Ernest Fraenkel , James Berry , Indu Navar , Raquel Norel

Recent advances in Artificial Intelligence (AI) and the exploration of noninvasive, objective biomarkers, such as speech signals, have encouraged the development of algorithms to support the early diagnosis of neurodegenerative diseases,…

Amyotrophic Lateral Sclerosis (ALS) is characterized as a rapidly progressive neurodegenerative disease that presents individuals with limited treatment options in the realm of medical interventions and therapies. The disease showcases a…

机器学习 · 计算机科学 2024-07-12 Ritesh Mehta , Aleksandar Pramov , Shashank Verma

Importance: Machine learning (ML) approaches to facial landmark localization carry great clinical potential for quantitative assessment of facial function as they enable high-throughput automated quantification of relevant facial metrics…

Early detection is crucial to prevent the progression of Alzheimer's disease (AD). Thus, specialists can begin preventive treatment as soon as possible. They demand fast and precise assessment in the diagnosis of AD in the earliest and…

Multiple Sclerosis (MS) is a severe neurological disease characterized by inflammatory lesions in the central nervous system. Hence, predicting inflammatory disease activity is crucial for disease assessment and treatment. However, MS…

图像与视频处理 · 电气工程与系统科学 2023-09-01 Chinmay Prabhakar , Hongwei Bran Li , Johannes C. Paetzold , Timo Loehr , Chen Niu , Mark Mühlau , Daniel Rueckert , Benedikt Wiestler , Bjoern Menze

Accurate facial expression analysis is an essential step in various clinical applications that involve physical and mental health assessments of older adults (e.g. diagnosis of pain or depression). Although remarkable progress has been…

计算机视觉与模式识别 · 计算机科学 2019-05-21 Azin Asgarian , Shun Zhao , Ahmed B. Ashraf , M. Erin Browne , Kenneth M. Prkachin , Alex Mihailidis , Thomas Hadjistavropoulos , Babak Taati

The upper motor neuron dysfunction in amyotrophic lateral sclerosis was quantified using triple stimulation and more focal transcranial magnetic stimulation techniques that were developed to reduce recording variability. These measurements…

神经元与认知 · 定量生物学 2016-09-29 Rahul Remanan , Viktor Sukhotskiy , Mona Shahbazi , Edward P. Furlani , Dale J. Lange

Texture analysis is a well-known research topic in computer vision and image processing and has many applications. Gradient-based texture methods have become popular in classification problems. For the first time we extend a well-known…

计算机视觉与模式识别 · 计算机科学 2017-09-26 G M Mashrur E Elahi , Sanjay Kalra , Yee-Hong Yang

Amyotrophic lateral sclerosis (ALS) is incurable neurological disorder with rapidly progressive course. Common early symptoms of ALS are difficulty in swallowing and speech. However, early acoustic manifestation of speech and voice symptoms…

声音 · 计算机科学 2021-01-12 Maxim Vashkevich , Yulia Rushkevich

Facial palsy is unilateral facial nerve weakness or paralysis of rapid onset with unknown causes. Automatically estimating facial palsy severeness can be helpful for the diagnosis and treatment of people suffering from it across the world.…

计算机视觉与模式识别 · 计算机科学 2022-03-31 Xuri Ge , Joemon M. Jose , Pengcheng Wang , Arunachalam Iyer , Xiao Liu , Hu Han

Background: Face morphometry has been shown to work as a diagnosis tool in a set of syndromes. Face similarities are usually indications of more complete genetic similarities. Purpose: To show preliminary results on the face morphometry…

种群与进化 · 定量生物学 2026-05-20 Roberto Herrero , Yoanna Martinez-Diaz , Heydi Mendez-Vazquez , Joan Nieves , Augusto Gonzalez

Early and accurate diagnosis of Alzheimer's disease (AD), a complex neurodegenerative disorder, requires analysis of heterogeneous biomarkers (e.g., neuroimaging, genetic risk factors, cognitive tests, and cerebrospinal fluid proteins)…

计算与语言 · 计算机科学 2025-10-16 Sophie Kearney , Shu Yang , Zixuan Wen , Bojian Hou , Duy Duong-Tran , Tianlong Chen , Jason Moore , Marylyn Ritchie , Li Shen
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