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相关论文: Automated Knowledge Modeling for Cancer Clinical P…

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This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

计算与语言 · 计算机科学 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Domain experts often rely on most recent knowledge for apprehending and disseminating specific biological processes that help them design strategies for developing prevention and therapeutic decision-making in various disease scenarios. A…

Biological systems are governed by structured molecular interactions, where pathways, regulatory circuits, and functional gene relationships shape cellular behavior and disease progression. Much of this knowledge is naturally represented as…

机器学习 · 计算机科学 2026-05-26 Yuwei Xue , Sakib Mostafa , James Zou , Joseph Liao , Maximilian Diehn , Ash A. Alizadeh , Lei Xing , Md. Tauhidul Islam

Patient-Centric Knowledge Graphs (PCKGs) represent an important shift in healthcare that focuses on individualized patient care by mapping the patient's health information in a holistic and multi-dimensional way. PCKGs integrate various…

Generative pre-trained transformer (GPT) models have shown promise in clinical entity and relation extraction tasks because of their precise extraction and contextual understanding capability. In this work, we further leverage the Unified…

计算与语言 · 计算机科学 2024-07-16 Kriti Bhattarai , Inez Y. Oh , Zachary B. Abrams , Albert M. Lai

The rapid advancements in Vision Language Models (VLMs) have prompted the development of multi-modal medical assistant systems. Despite this progress, current models still have inherent probabilistic uncertainties, often producing erroneous…

计算机视觉与模式识别 · 计算机科学 2025-07-15 Xiao Liang , Di Wang , Zhicheng Jiao , Ronghan Li , Pengfei Yang , Quan Wang , Tat-Seng Chua

Cancer subtyping is crucial for understanding the nature of tumors and providing suitable therapy. However, existing labelling methods are medically controversial, and have driven the process of subtyping away from teaching signals.…

机器学习 · 计算机科学 2022-11-15 Zheng Chen , Lingwei Zhu , Ziwei Yang , Takashi Matsubara

Clinical trial records are variable resources or the analysis of patients and diseases. Information extraction from free text such as eligibility criteria and summary of results and conclusions in clinical trials would better support…

计算与语言 · 计算机科学 2020-01-01 Yingcheng Sun , Kenneth Loparo

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

计算与语言 · 计算机科学 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

Genomics, especially multi-omics, has made precision medicine feasible. The completion and publicly accessible multi-omics resource with clinical outcome, such as The Cancer Genome Atlas (TCGA) is a great test bed for developing…

基因组学 · 定量生物学 2020-08-31 Lana X Garmire

Healthcare domain generates a lot of unstructured and semi-structured text. Natural Language processing (NLP) has been used extensively to process this data. Deep Learning based NLP especially Large Language Models (LLMs) such as BERT have…

计算与语言 · 计算机科学 2023-01-11 Kunal Suri , Atul Singh , Prakhar Mishra , Swapna Sourav Rout , Rajesh Sabapathy

An effective and efficient review of construction contracts is essential for minimizing construction projects losses, but current methods are time-consuming and error-prone. Studies using methods based on Natural Language Processing (NLP)…

人工智能 · 计算机科学 2025-05-20 Chunmo Zheng , Saika Wong , Xing Su , Yinqiu Tang , Ahsan Nawaz , Mohamad Kassem

External knowledge is often useful for natural language understanding tasks. We introduce a contextual text representation model called Conceptual-Contextual (CC) embeddings, which incorporates structured knowledge into text…

计算与语言 · 计算机科学 2020-03-13 Xiao Zhang , Dejing Dou , Ji Wu

Large language models (LLMs) have recently emerged as powerful tools, finding many medical applications. LLMs' ability to coalesce vast amounts of information from many sources to generate a response-a process similar to that of a human…

Current multimodal survival prediction methods typically rely on pathology images (WSIs) and genomic data, both of which are high-dimensional and redundant, making it difficult to extract discriminative features from them and align…

计算机视觉与模式识别 · 计算机科学 2025-12-17 Chenyu Zhao , Yingxue Xu , Fengtao Zhou , Yihui Wang , Hao Chen

Cancer genomes exhibit a large number of different alterations that affect many genes in a diverse manner. It is widely believed that these alterations follow combinatorial patterns that have a strong connection with the underlying…

机器学习 · 计算机科学 2016-01-26 Jack P. Hou , Amin Emad , Gregory J. Puleo , Jian Ma , Olgica Milenkovic

Shallow Convolution Neural Network (CNN) is a time-tested tool for the information extraction from cancer pathology reports. Shallow CNN performs competitively on this task to other deep learning models including BERT, which holds the…

计算与语言 · 计算机科学 2020-08-05 Abhishek K Dubey , Alina Peluso , Jacob Hinkle , Devanshu Agarawal , Zilong Tan

Knowledge graphs (KGs) serve as powerful tools for organizing and representing structured knowledge. While their utility is widely recognized, challenges persist in their automation and completeness. Despite efforts in automation and the…

人工智能 · 计算机科学 2024-05-07 Mutahira Khalid , Raihana Rahman , Asim Abbas , Sushama Kumari , Iram Wajahat , Syed Ahmad Chan Bukhari

Deep learning models have achieved promising results in breast cancer classification, yet their 'black-box' nature raises interpretability concerns. This research addresses the crucial need to gain insights into the decision-making process…

计算机视觉与模式识别 · 计算机科学 2024-08-26 Ann-Kristin Balve , Peter Hendrix

Medical knowledge graphs (KGs) are essential for clinical decision support and biomedical research, yet they often exhibit incompleteness due to knowledge gaps and structural limitations in medical coding systems. This issue is particularly…

计算与语言 · 计算机科学 2025-04-01 Xinyu Yao , Aditya Sannabhadti , Holly Wiberg , Karmel S. Shehadeh , Rema Padman