相关论文: Automated Knowledge Modeling for Cancer Clinical P…

Large language models (LLMs) show promise for diagnostic reasoning but often lack reliable, knowledge grounded inference. Knowledge graphs (KGs), such as the Unified Medical Language System (UMLS), offer structured biomedical knowledge that…

Background Precise prediction of cancer types is vital for cancer diagnosis and therapy. Important cancer marker genes can be inferred through predictive model. Several studies have attempted to build machine learning models for this task…

The study of cellular signalling pathways and their deregulation in disease states, such as cancer, is a large and extremely complex task. Indeed, these systems involve many parts and processes but are studied piecewise and their…

Here, we describe one of the first Web-scale hybrid Knowledge Graph (KG)-Large Language Model (LLM), populated with the latest peer-reviewed medical knowledge on colorectal Cancer. It is currently being evaluated to assist with both medical…

Recent advancements in image classification have demonstrated that contrastive learning (CL) can aid in further learning tasks by acquiring good feature representation from a limited number of data samples. In this paper, we applied CL to…

The advancement of computer-aided detection systems had a significant impact on clinical analysis and decision-making on human disease. Lung cancer requires more attention among the numerous diseases being examined because it affects both…

The accurate diagnosis of pathological subtypes of lung cancer is of paramount importance for follow-up treatments and prognosis managements. Assessment methods utilizing deep learning technologies have introduced novel approaches for…

With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

As Deep Convolutional Neural Networks (DCNNs) have shown robust performance and results in medical image analysis, a number of deep-learning-based tumor detection methods were developed in recent years. Nowadays, the automatic detection of…

Large Language Models (LLMs) are increasingly used for question answering over scientific research papers. Existing retrieval augmentation methods often rely on isolated text chunks or concepts, but overlook deeper semantic connections…

Convolutional neural networks (CNNs) have been recently used for a variety of histology image analysis. However, availability of a large dataset is a major prerequisite for training a CNN which limits its use by the computational pathology…

The digitalization of stored information in hospitals now allows for the exploitation of medical data in text format, as electronic health records (EHRs), initially gathered for other purposes than epidemiology. Manual search and analysis…

Citation recommendation for research papers is a valuable task that can help researchers improve the quality of their work by suggesting relevant related work. Current approaches for this task rely primarily on the text of the papers and…

The advent of large language models (LLMs) has revolutionized the integration of knowledge graphs (KGs) in biomedical and cognitive sciences, overcoming limitations in traditional machine learning methods for capturing intricate semantic…

Predicting molecular properties is a critical component of drug discovery. Recent advances in deep learning, particularly Graph Neural Networks (GNNs), have enabled end-to-end learning from molecular structures, reducing reliance on manual…

Cancer clinics capture disease data at various scales, from genetic to organ level. Current bioinformatic methods struggle to handle the heterogeneous nature of this data, especially with missing modalities. We propose PARADIGM, a Graph…

Diagnosis of a clinical condition is a challenging task, which often requires significant medical investigation. Previous work related to diagnostic inferencing problems mostly consider multivariate observational data (e.g. physiological…

The rapid advancement of large language models (LLMs) has opened new boundaries in the extraction and synthesis of medical knowledge, particularly within evidence synthesis. This paper reviews the state-of-the-art applications of LLMs in…

Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a…

Tissue characterization has long been an important component of Computer Aided Diagnosis (CAD) systems for automatic lesion detection and further clinical planning. Motivated by the superior performance of deep learning methods on various…