相关论文: Interpreting deep embeddings for disease progressi…

For decades, a variety of predictive approaches have been proposed and evaluated in terms of their prediction capability for Alzheimer's Disease (AD) and its precursor - mild cognitive impairment (MCI). Most of them focused on prediction or…

In this paper, an innovative multi-modal deep learning model is proposed to deeply integrate heterogeneous information from medical images and clinical reports. First, for medical images, convolutional neural networks were used to extract…

This work presents an unsupervised deep discriminant analysis for clustering. The method is based on deep neural networks and aims to minimize the intra-cluster discrepancy and maximize the inter-cluster discrepancy in an unsupervised…

Joint models for longitudinal and time-to-event data are commonly used in longitudinal studies to forecast disease trajectories over time. While there are many advantages to joint modeling, the standard forms suffer from limitations that…

People with diabetes need insulin delivery to effectively manage their blood glucose levels, especially after meals, because their bodies either do not produce enough insulin or cannot fully utilize it. Accurate insulin delivery starts with…

Diabetes is a global raising pandemic. Diabetes patients are at risk of developing foot ulcer that usually leads to limb amputation. In order to develop a self monitoring mobile application, in this work, we propose a novel deep subspace…

Spectral Embedding (SE) has often been used to map data points from non-linear manifolds to linear subspaces for the purpose of classification and clustering. Despite significant advantages, the subspace structure of data in the original…

People with diabetes must carefully monitor their blood glucose levels, especially after eating. Blood glucose regulation requires a proper combination of food intake and insulin boluses. Glucose prediction is vital to avoid dangerous…

A systematic analysis of the cell behavior requires automated approaches for cell segmentation and tracking. While deep learning has been successfully applied for the task of cell segmentation, there are few approaches for simultaneous cell…

Unlike natural images, medical images often have intrinsic characteristics that can be leveraged for neural network learning. For example, images that belong to different stages of a disease may continuously follow a certain progression…

The detection and normalization of diseases in biomedical texts are key biomedical natural language processing tasks. Disease names need not only be identified, but also normalized or linked to clinical taxonomies describing diseases such…

Deep neural networks are powerful tools for modelling non-linear patterns and are very effective when the input data is homogeneous such as images and texts. In recent years, there have been attempts to apply neural nets to heterogeneous…

There have been rapid developments in model-based clustering of graphs, also known as block modelling, over the last ten years or so. We review different approaches and extensions proposed for different aspects in this area, such as the…

Recently, it has become progressively more evident that classic diagnostic labels are unable to reliably describe the complexity and variability of several clinical phenotypes. This is particularly true for a broad range of neuropsychiatric…

Sepsis is a life-threatening condition caused by a dysregulated host response to infection. Recently, researchers have hypothesized that sepsis consists of a heterogeneous spectrum of distinct subtypes, motivating several studies to…

Obesity is a major health problem, increasing the risk of various major chronic diseases, such as diabetes, cancer, and stroke. While the role of obesity identified by cross-sectional BMI recordings has been heavily studied, the role of BMI…

Mining relationships between treatment(s) and medical problem(s) is vital in the biomedical domain. This helps in various applications, such as decision support system, safety surveillance, and new treatment discovery. We propose a deep…

Automated learning of patients demographics can be seen as multi-label problem where a patient model is based on different race and gender groups. The resulting model can be further integrated into Privacy-Preserving Data Mining, where it…

Recently, bladder cancer has been significantly increased in terms of incidence and mortality. Currently, two subtypes are known based on tumour growth: non-muscle invasive (NMIBC) and muscle-invasive bladder cancer (MIBC). In this work, we…

Interpreting the learning dynamics of neural networks can provide useful insights into how networks learn and the development of better training and design approaches. We present an approach to interpret learning in neural networks by…