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Clinical notes in Electronic Health Records (EHR) present rich documented information of patients to inference phenotype for disease diagnosis and study patient characteristics for cohort selection. Unsupervised user embedding aims to…

计算与语言 · 计算机科学 2022-03-30 Xiaolei Huang , Franck Dernoncourt , Mark Dredze

We propose a convolution neural network based algorithm for simultaneously diagnosing diabetic retinopathy and highlighting suspicious regions. Our contributions are two folds: 1) a network termed Zoom-in-Net which mimics the zoom-in…

计算机视觉与模式识别 · 计算机科学 2017-06-15 Zhe Wang , Yanxin Yin , Jianping Shi , Wei Fang , Hongsheng Li , Xiaogang Wang

Diabetes is a chronic metabolic disease characterized by elevated blood glucose levels, leading to complications like heart disease, kidney failure, and nerve damage. Accurate state-level predictions are vital for effective healthcare…

机器学习 · 计算机科学 2025-06-18 Vuong M. Ngo , Tran Quang Vinh , Patricia Kearney , Mark Roantree

This study explored healthcare professionals' perspectives on the management of Type 1 Diabetes Mellitus (T1DM) through a two-part questionnaire. The first part examined how clinicians prioritise and apply current clinical guidelines,…

人机交互 · 计算机科学 2026-03-27 Mohammed Basheikh , Rujiravee Kongdee , Hood Thabit , Bijan Parsia , Sarah Clinch , Simon Harper

Term clustering is important in biomedical knowledge graph construction. Using similarities between terms embedding is helpful for term clustering. State-of-the-art term embeddings leverage pretrained language models to encode terms, and…

计算与语言 · 计算机科学 2022-04-04 Sihang Zeng , Zheng Yuan , Sheng Yu

Clustering is central to many data-driven application domains and has been studied extensively in terms of distance functions and grouping algorithms. Relatively little work has focused on learning representations for clustering. In this…

机器学习 · 计算机科学 2016-05-26 Junyuan Xie , Ross Girshick , Ali Farhadi

Diabetes is a chronic disease with a significant global health burden, requiring multi-stakeholder collaboration for optimal management. Large language models (LLMs) have shown promise in various healthcare scenarios, but their…

We propose a novel semiparametric model for the joint distribution of a continuous longitudinal outcome and the baseline covariates using an enriched Dirichlet process (EDP) prior. This joint model decomposes into a linear mixed model for…

统计方法学 · 统计学 2018-06-08 Bret Zeldow , James Flory , Alisa Stephens-Shields , Marsha Raebel , Jason Roy

Understanding how biomarker distributions evolve over time is a central challenge in digital health and chronic disease monitoring. In diabetes, changes in the distribution of glucose measurements can reveal patterns of disease progression…

机器学习 · 统计学 2026-03-26 Antonio Álvarez-López , Marcos Matabuena

The goal of lifetime clustering is to develop an inductive model that maps subjects into $K$ clusters according to their underlying (unobserved) lifetime distribution. We introduce a neural-network based lifetime clustering model that can…

机器学习 · 计算机科学 2019-10-03 S Chandra Mouli , Leonardo Teixeira , Jennifer Neville , Bruno Ribeiro

Background: Type 2 diabetes mellitus (T2DM) is increasingly recognised as a systemic disease characterised by coordinated dysfunction across metabolic, renal, lipid, and inflammatory pathways. Existing clinical assessments often fail to…

机器学习 · 计算机科学 2026-05-26 Mini Han Wang , Liting Huang , Wei Hong , Boonthawan Wingwon

Clustering is commonly performed as an initial analysis step for uncovering structure in 'omics datasets, e.g. to discover molecular subtypes of disease. The high-throughput, high-dimensional nature of these datasets means that they provide…

统计方法学 · 统计学 2023-03-02 Paul D. W. Kirk , Filippo Pagani , Sylvia Richardson

Median clustering extends popular neural data analysis methods such as the self-organizing map or neural gas to general data structures given by a dissimilarity matrix only. This offers flexible and robust global data inspection methods…

机器学习 · 计算机科学 2009-09-04 Barbara Hammer , Alexander Hasenfuß , Fabrice Rossi

In this project, we developed a deep learning system applied to human retina images for medical diagnostic decision support. The retina images were provided by EyePACS. These images were used in the framework of a Kaggle contest, whose…

计算机视觉与模式识别 · 计算机科学 2018-07-25 Maria Camila Alvarez Trivino , Jeremie Despraz , Jesus Alfonso Lopez Sotelo , Carlos Andres Pena

Clinical time series data are critical for patient monitoring and predictive modeling. These time series are typically multivariate and often comprise hundreds of heterogeneous features from different data sources. The grouping of features…

机器学习 · 计算机科学 2025-11-12 Fedor Sergeev , Manuel Burger , Polina Leshetkina , Vincent Fortuin , Gunnar Rätsch , Rita Kuznetsova

Characterization of a patient clinical phenotype is central to biomedical informatics. ICD codes, assigned to inpatient encounters by coders, is important for population health and cohort discovery when clinical information is limited.…

Subgroup identification (clustering) is an important problem in biomedical research. Gene expression profiles are commonly utilized to define subgroups. Longitudinal gene expression profiles might provide additional information on disease…

统计方法学 · 统计学 2016-09-27 Jiehuan Sun , Jose D. Herazo-Maya , Naftali Kaminski , Hongyu Zhao , Joshua L. Warren

In the healthcare sector, the application of deep learning technologies has revolutionized data analysis and disease forecasting. This is particularly evident in the field of diabetes, where the deep analysis of Electronic Health Records…

机器学习 · 计算机科学 2024-12-06 Huadong Pang , Li Zhou , Yiping Dong , Peiyuan Chen , Dian Gu , Tianyi Lyu , Hansong Zhang

Due to the complexity of cancer, clustering algorithms have been used to disentangle the observed heterogeneity and identify cancer subtypes that can be treated specifically. While kernel based clustering approaches allow the use of more…

机器学习 · 统计学 2018-11-21 Nora K. Speicher , Nico Pfeifer

The imperative for early detection of type 2 diabetes mellitus (T2DM) is challenged by its asymptomatic onset and dependence on suboptimal clinical diagnostic tests, contributing to its widespread global prevalence. While research into…

机器学习 · 计算机科学 2024-12-17 Sanjana Gundapaneni , Zhuo Zhi , Miguel Rodrigues