相关论文: Interpreting deep embeddings for disease progressi…

The adoption of deep learning in healthcare is hindered by their "black box" nature. In this paper, we explore the RETAIN architecture for the task of glusose forecasting for diabetic people. By using a two-level attention mechanism, the…

We present a novel methodology for integrating high resolution longitudinal data with the dynamic prediction capabilities of survival models. The aim is two-fold: to improve the predictive power while maintaining interpretability of the…

Diabetes is one of the most prevalent diseases worldwide, characterized by persistently high blood sugar levels, capable of damaging various internal organs and systems. Diabetes patients require routine check-ups, resulting in a time…

Motivation: There is a growing need to integrate mechanistic models of biological processes with computational methods in healthcare in order to improve prediction. We apply data assimilation in the context of Type 2 diabetes to understand…

People with diabetes have to manage their blood glucose level to keep it within an appropriate range. Predicting whether future glucose values will be outside the healthy threshold is of vital importance in order to take corrective actions…

Many clinical deep learning algorithms are population-based and difficult to interpret. Such properties limit their clinical utility as population-based findings may not generalize to individual patients and physicians are reluctant to…

The increase in availability of longitudinal electronic health record (EHR) data is leading to improved understanding of diseases and discovery of novel phenotypes. The majority of clustering algorithms focus only on patient trajectories,…

In this report, we applied integrated gradients to explaining a neural network for diabetic retinopathy detection. The integrated gradient is an attribution method which measures the contributions of input to the quantity of interest. We…

With the advancement in drug development, multiple treatments are available for a single disease. Patients can often benefit from taking multiple treatments simultaneously. For example, patients in Clinical Practice Research Datalink (CPRD)…

In electronic health records (EHRs), clustering patients and distinguishing disease subtypes are key tasks to elucidate pathophysiology and aid clinical decision-making. However, clustering in healthcare informatics is still based on…

Disease progression modeling (DPM) involves using mathematical frameworks to quantitatively measure the severity of how certain disease progresses. DPM is useful in many ways such as predicting health state, categorizing disease stages, and…

Disease progression models are widely used to inform the diagnosis and treatment of many progressive diseases. However, a significant limitation of existing models is that they do not account for health disparities that can bias the…

The automatic discovery of a model to represent the history of encounters of a group of patients with the healthcare system -- the so-called "pathway of patients" -- is a new field of research that supports clinical and organisational…

Trace clustering has increasingly been applied to find homogenous process executions. However, current techniques have difficulties in finding a meaningful and insightful clustering of patients on the basis of healthcare data. The resulting…

Clustering artworks is difficult for several reasons. On the one hand, recognizing meaningful patterns in accordance with domain knowledge and visual perception is extremely difficult. On the other hand, applying traditional clustering and…

In this paper, we propose a deep generative time series approach using latent temporal processes for modeling and holistically analyzing complex disease trajectories. We aim to find meaningful temporal latent representations of an…

Consensus clustering fuses diverse basic partitions (i.e., clustering results obtained from conventional clustering methods) into an integrated one, which has attracted increasing attention in both academic and industrial areas due to its…

Effective management of Type 1 Diabetes requires continuous glucose monitoring and precise insulin adjustments to prevent hyperglycemia and hypoglycemia. With the growing adoption of wearable glucose monitors and mobile health applications,…

Understanding the functional roles of financial institutions within interconnected markets is critical for effective supervision, systemic risk assessment, and resolution planning. We propose an interpretable role-based clustering approach…

In the U.S., over a third of adults are pre-diabetic, with 80\% unaware of their status. This underlines the need for better glucose monitoring to prevent type 2 diabetes and related heart diseases. Existing wearable glucose monitors are…