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We describe a continuous-time modelling framework for biological population dynamics that accounts for demographic noise. In the spirit of the methodology used by statistical physicists, transitions between the states of the system are…

种群与进化 · 定量生物学 2018-07-19 George W. A. Constable , Alan J. McKane

We consider an individual-based spatially structured population for Darwinian evolution in an asexual population. The individuals move randomly on a bounded continuous space according to a reflected brownian motion. The dynamics involves…

概率论 · 数学 2015-09-08 Helene Leman

We consider an exponentially growing population of cells undergoing mutations and ask about the effect of reproductive fluctuations (genetic drift) on its long-term evolution. We combine first step analysis with the stochastic dynamics of a…

种群与进化 · 定量生物学 2022-03-14 Arman Angaji , Christoph Velling , Johannes Berg

We consider a particle system in continuous time, discrete population, with spatial motion and nonlocal branching. The offspring's weights and their number may depend on the mother's weight. Our setting captures, for instance, the processes…

概率论 · 数学 2012-10-12 Bertrand Cloez

The sample frequency spectrum of a segregating site is the probability distribution of a sample of alleles from a genetic locus, conditional on observing the sample to have more than one clearly different phenotypes. We present a model for…

概率论 · 数学 2014-05-13 Arka Bhattacharya

Coevolving and competing species or game-theoretic strategies exhibit rich and complex dynamics for which a general theoretical framework based on finite populations is still lacking. Recently, an explicit mean-field description in the form…

统计力学 · 物理学 2007-05-23 Arne Traulsen , Jens Christian Claussen , Christoph Hauert

General genealogical processes such as $\Lambda$- and $\Xi$-coalescents, which respectively model multiple and simultaneous mergers, have important applications in studying marine species, strong positive selection, recurrent selective…

种群与进化 · 定量生物学 2016-05-10 Jeffrey P. Spence , John A. Kamm , Yun S. Song

A fundamental problem in the fields of population genetics, evolution, and community ecology, is the fate of a single mutant, or invader, introduced in a finite population of wild types. For a fixed-size community of $N$ individuals, with…

种群与进化 · 定量生物学 2017-10-25 Matan Danino , Nadav M. Shnerb

We study the evolutionary dynamics of a phenotypically structured population in a changing environment , where the environmental conditions vary with a linear trend but in an oscillatory manner. Such phenomena can be described by parabolic…

偏微分方程分析 · 数学 2021-05-04 Susely Figueroa Iglesias , Sepideh Mirrahimi

We analyze the long-term stability of a stochastic model designed to illustrate the adaptation of a population to variation in its environment. A piecewise-deterministic process modeling adaptation is coupled to a Feller logistic diffusion…

概率论 · 数学 2021-09-14 Aurélien Velleret

1 Sharp prediction of extinction times is needed in biodiversity monitoring and conservation management. 2 The Galton-Watson process is a classical stochastic model for describing population dynamics. Its evolution is like the matrix…

应用统计 · 统计学 2019-01-29 B Cloez , T Daufresne , M Kerioui , B Fontez

Over time, a population acquires neutral genetic substitutions as a consequence of random drift. A famous result in population genetics asserts that the rate, $K$, at which these substitutions accumulate in the population coincides with the…

We study stochastic evolutionary game dynamics in a population of finite size. Individuals in the population are divided into two dynamically evolving groups. The structure of the population is formally described by a Wright-Fisher type…

The role of the selection pressure and mutation amplitude on the behavior of a single-species population evolving on a two-dimensional lattice, in a periodically changing environment, is studied both analytically and numerically. The…

种群与进化 · 定量生物学 2009-11-13 Ioana Bena , Michel Droz , Janusz Szwabinski , Andrzej Pekalski

We investigate two stochastic models of a growing population subject to selection and mutation. In our models each individual carries a fitness which determines its mean offspring number. Many of these offspring inherit their parent's…

概率论 · 数学 2023-07-12 Su-Chan Park , Joachim Krug , Léo Touzo , Peter Mörters

The number of fixed mutations accumulated in an evolving population often displays a variance that is significantly larger than the mean (the overdispersed molecular clock). By examining a generic evolutionary process on a neutral network…

种群与进化 · 定量生物学 2009-11-13 Alpan Raval

The environment in which a population evolves can have a crucial impact on selection. We study evolutionary dynamics in finite populations of fixed size in a changing environment. The population dynamics are driven by birth and death…

种群与进化 · 定量生物学 2014-09-01 Peter Ashcroft , Philipp M Altrock , Tobias Galla

In this article, a stochastic individual-based model describing Darwinian evolution of asexual, phenotypic trait-structured population, is studied. We consider a large population with constant population size characterised by a resampling…

概率论 · 数学 2024-07-09 Nicolas Champagnat , Vincent Hass

In cancer genomics, it is of great importance to distinguish driver mutations, which contribute to cancer progression, from causally neutral passenger mutations. We propose a random-effect regression approach to estimate the effects of…

统计方法学 · 统计学 2023-06-30 Kin Yau Wong , Donglin Zeng , D. Y. Lin

In evolutionary dynamics, the probability that a mutation spreads through the whole population, having arisen in a single individual, is known as the fixation probability. In general, it is not possible to find the fixation probability…

种群与进化 · 定量生物学 2010-10-26 Valmir C. Barbosa , Raul Donangelo , Sergio R. Souza