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Breast cancer is one of the most threatening diseases in women's life; thus, the early and accurate diagnosis plays a key role in reducing the risk of death in a patient's life. Mammography stands as the reference technique for breast…

机器学习 · 计算机科学 2023-05-05 Juan Zuluaga-Gomez

Early detection of clinical outcomes such as cancer may be predicted based on longitudinal biomarker measurements. Tracking longitudinal biomarkers as a way to identify early disease onset may help to reduce mortality from diseases like…

The Cancer Genome Atlas (TCGA) provides researchers with clinicopathological data and genomic characterizations of various carcinomas. These data sets include expression microarrays for genes and microRNAs -- short, non-coding strands of…

定量方法 · 定量生物学 2013-07-05 Siddharth G. Reddy , Weimin Xiao , Preethi H. Gunaratne

Background: Lung cancer was known as primary cancers and the survival rate of cancer is about 15%. Early detection of lung cancer is the leading factor in survival rate. All symptoms (features) of lung cancer do not appear until the cancer…

人工智能 · 计算机科学 2016-01-26 Mitra Montazeri , Mahdieh Soleymani Baghshah , Ahmad Enhesari

This paper primarily addresses a dataset relating to cellular, chemical and physical conditions of patients gathered at the time they are operated upon to remove colorectal tumours. This data provides a unique insight into the biochemical…

机器学习 · 计算机科学 2016-11-17 Christopher Roadknight , Durga Suryanarayanan , Uwe Aickelin , John Scholefield , Lindy Durrant

Deep Learning (DL) can predict biomarkers from cancer histopathology. Several clinically approved applications use this technology. Most approaches, however, predict categorical labels, whereas biomarkers are often continuous measurements.…

Many machine learning models have been proposed to classify phenotypes from gene expression data. In addition to their good performance, these models can potentially provide some understanding of phenotypes by extracting explanations for…

基因组学 · 定量生物学 2024-02-05 Myriam Bontonou , Anaïs Haget , Maria Boulougouri , Benjamin Audit , Pierre Borgnat , Jean-Michel Arbona

The advent of large scale, high-throughput genomic screening has introduced a wide range of tests for diagnostic purposes. Prominent among them are tests using miRNA expression levels. Genomics and proteomics now provide expression levels…

基因组学 · 定量生物学 2016-11-08 Neerja Garikipati

The choice of the most effective treatment may eventually be influenced by breast cancer survival prediction. To predict the chances of a patient surviving, a variety of techniques were employed, such as statistical, machine learning, and…

机器学习 · 计算机科学 2023-04-18 Khaoula Chtouki , Maryem Rhanoui , Mounia Mikram , Kamelia Amazian , Siham Yousfi

In this work, we investigate the importance of ethnicity in colorectal cancer survivability prediction using machine learning techniques and the SEER cancer incidence database. We compare model performances for 2-year survivability…

机器学习 · 计算机科学 2019-01-15 Samuel Li , Talayeh Razzaghi

Pancreatic cancer will soon be the second leading cause of cancer-related death in Western society. Imaging techniques such as CT, MRI and ultrasound typically help providing the initial diagnosis, but histopathological assessment is still…

图像与视频处理 · 电气工程与系统科学 2022-01-26 Pierpaolo Vendittelli , Esther M. M. Smeets , Geert Litjens

Identifying peri-pancreatic edema is a pivotal indicator for identifying disease progression and prognosis, emphasizing the critical need for accurate detection and assessment in pancreatitis diagnosis and management. This study…

Pancreatic ductal adenocarcinoma (PDAC), one of the deadliest solid malignancies, is often detected at a late and inoperable stage. Retrospective reviews of prediagnostic CT scans, when conducted by expert radiologists aware that the…

This work presents comprehensive results to detect in the early stage the pancreatic neuroendocrine tumors (PNETs), a group of endocrine tumors arising in the pancreas, which are the second common type of pancreatic cancer, by checking the…

图像与视频处理 · 电气工程与系统科学 2020-04-07 Zhuotun Zhu , Yongyi Lu , Wei Shen , Elliot K. Fishman , Alan L. Yuille

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. Several diagnostic methods, such as imaging modalities and Serum Alpha-Fetoprotein (AFP) testing, have been used for HCC detection; however,…

基因组学 · 定量生物学 2025-07-02 Aram Ansary Ogholbake , Qiang Cheng

The research reported in this paper identifies the epigenetic biomarker (methylation beta pattern) of breast cancer. Many cancers are triggered by abnormal gene expression levels caused by aberrant methylation of CpG sites in the DNA. In…

基因组学 · 定量生物学 2019-10-16 Maxim Vaysburd

Tumor growth prediction, a highly challenging task, has long been viewed as a mathematical modeling problem, where the tumor growth pattern is personalized based on imaging and clinical data of a target patient. Though mathematical models…

计算机视觉与模式识别 · 计算机科学 2017-06-05 Ling Zhang , Le Lu , Ronald M. Summers , Electron Kebebew , Jianhua Yao

Gastric cancer ranks as the fifth most common and fourth most lethal cancer globally, with a dismal 5-year survival rate of approximately 20%. Despite extensive research on its pathobiology, the prognostic predictability remains inadequate,…

图像与视频处理 · 电气工程与系统科学 2025-03-24 Marco Usai , Andrea Loddo , Alessandra Perniciano , Maurizio Atzori , Cecilia Di Ruberto

Gene selection plays a pivotal role in oncology research for improving outcome prediction accuracy and facilitating cost-effective genomic profiling for cancer patients. This paper introduces two gene selection strategies for deep…

基因组学 · 定量生物学 2024-03-05 Akhila Krishna , Ravi Kant Gupta , Pranav Jeevan , Amit Sethi

Time-to-event prediction, e.g. cancer survival analysis or hospital length of stay, is a highly prominent machine learning task in medical and healthcare applications. However, only a few interpretable machine learning methods comply with…

计算机视觉与模式识别 · 计算机科学 2024-11-25 Hubert Baniecki , Bartlomiej Sobieski , Patryk Szatkowski , Przemyslaw Bombinski , Przemyslaw Biecek