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Large language model (LLM)-powered assistants have recently integrated memory mechanisms that record user preferences, leading to more personalized and user-aligned responses. However, irrelevant personalized memories are often introduced…

计算与语言 · 计算机科学 2026-01-26 Xueyang Feng , Weinan Gan , Xu Chen , Quanyu Dai , Yong Liu

Understanding interaction effects among variables is important for regression modeling in various applications. The conventional approach of quantifying interactions as the product of variables often lacks clear interpretability, especially…

统计方法学 · 统计学 2026-05-21 Kexin Xie , Xinwei Deng

Simulations of complex physical systems are typically realized by discretizing partial differential equations (PDEs) on unstructured meshes. While neural networks have recently been explored for surrogate and reduced order modeling of PDE…

机器学习 · 计算机科学 2021-10-27 Jiayang Xu , Aniruddhe Pradhan , Karthik Duraisamy

Nonlinear Mixed effects models are hidden variables models that are widely used in many fields such as pharmacometrics. In such models, the distribution characteristics of hidden variables can be specified by including several parameters…

统计方法学 · 统计学 2021-10-19 Edouard Ollier

Mood disorders are common and associated with significant morbidity and mortality. Early diagnosis has the potential to greatly alleviate the burden of mental illness and the ever increasing costs to families and society. Mobile devices…

人机交互 · 计算机科学 2018-08-30 He Huang , Bokai Cao , Philip S. Yu , Chang-Dong Wang , Alex D. Leow

The field of neuroimaging has truly become data rich, and novel analytical methods capable of gleaning meaningful information from large stores of imaging data are in high demand. Those methods that might also be applicable on the level of…

Nonlinear mixed effects models represent a powerful tool to simultaneously analyze data from several individuals. In this study a compartmental model of leucine kinetics is examined and extended with a stochastic differential equation to…

定量方法 · 定量生物学 2011-01-05 Martin Berglund , Mikael Sunnåker , Martin Adiels , Mats Jirstrand , Bernt Wennberg

Modern neural networks (NNs) often achieve high predictive accuracy but are poorly calibrated, producing overconfident predictions even when wrong. This miscalibration poses serious challenges in applications where reliable uncertainty…

机器学习 · 计算机科学 2025-09-12 Pedro Mendes , Paolo Romano , David Garlan

We propose the Intuitive Reasoning Network (IRENE) - a novel neural model for intuitive psychological reasoning about agents' goals, preferences, and actions that can generalise previous experiences to new situations. IRENE combines a graph…

人工智能 · 计算机科学 2023-12-13 Matteo Bortoletto , Lei Shi , Andreas Bulling

The predictive advantage of combining several different predictive models is widely accepted. Particularly in time series forecasting problems, this combination is often dynamic to cope with potential non-stationary sources of variation…

机器学习 · 统计学 2021-04-06 Vitor Cerqueira , Luis Torgo , Carlos Soares , Albert Bifet

Network meta-analysis (NMA) allows the combination of direct and indirect evidence from a set of randomized clinical trials. Performing NMA using individual patient data (IPD) is considered as a "gold standard" approach as it provides…

统计方法学 · 统计学 2021-10-22 Edouard Ollier , Pierre Blanchard , Gwénaël Le Teuff , Stefan Michiels

Objective: In randomized clinical trials, prediction models can be used to explore the relationships between patients' variables (e.g., clinical, pathological, or lifestyle variables, and also biomarker or genomic data) and treatment effect…

定量方法 · 定量生物学 2026-02-03 Elvire Roblin , Paul-Henry Cournède , Stefan Michiels

This paper considers nonparametric regression from strongly mixing observations. The proposed approach is based on deep neural networks with minimum error entropy (MEE) principle. We study two estimators: the non-penalized deep neural…

机器学习 · 统计学 2026-03-13 William Kengne , Modou Wade

We present a computational motivation for restricted maximum likelihood (REML) estimation in linear mixed models using an expectation--maximization (EM) algorithm. At each iteration, maximum likelihood (ML) and REML solve the same…

统计计算 · 统计学 2026-02-11 Andrew T. Karl

Depression is ranked as the largest contributor to global disability and is also a major reason for suicide. Still, many individuals suffering from forms of depression are not treated for various reasons. Previous studies have shown that…

计算与语言 · 计算机科学 2024-10-30 Marcel Trotzek , Sven Koitka , Christoph M. Friedrich

Maximum likelihood or restricted maximum likelihood (REML) estimates of the parameters in linear mixed-effects models can be determined using the lmer function in the lme4 package for R. As for most model-fitting functions in R, the model…

统计计算 · 统计学 2014-06-24 Douglas Bates , Martin Mächler , Ben Bolker , Steve Walker

With the widespread adoption of large language models (LLMs), understanding their personality representation mechanisms has become critical. As a novel paradigm in Personality Editing, most existing methods employ neuron-editing to locate…

计算与语言 · 计算机科学 2026-05-01 Lifan Zheng , Xue Yang , Jiawei Chen , Chenyan Wu , Jingyuan Zhang , Fanheng Kong , Xinyi Zeng , Xiang Chen , Yu Tian

Conventional federated learning (FL) frameworks often suffer from training degradation due to data uncertainty and heterogeneity across local clients. Probabilistic approaches such as Bayesian neural networks (BNNs) can mitigate this issue…

机器学习 · 计算机科学 2026-03-20 Ratun Rahman , Dinh C. Nguyen

Understanding and interpreting how machine learning (ML) models make decisions have been a big challenge. While recent research has proposed various technical approaches to provide some clues as to how an ML model makes individual…

机器学习 · 计算机科学 2018-11-09 Wenbo Guo , Sui Huang , Yunzhe Tao , Xinyu Xing , Lin Lin

In this paper the application of uncertainty modeling to convolutional neural networks is evaluated. A novel method for adjusting the network's predictions based on uncertainty information is introduced. This allows the network to be either…

计算机视觉与模式识别 · 计算机科学 2016-12-23 Rene Grzeszick , Sebastian Sudholt , Gernot A. Fink