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The field of histology relies heavily on antiquated tissue processing and staining techniques that limit the efficiency of pathologic diagnoses of cancer and other diseases. Current staining and advanced labeling methods are often…

We propose a Deep learning-based weak label learning method for analyzing whole slide images (WSIs) of Hematoxylin and Eosin (H&E) stained tumor tissue not requiring pixel-level or tile-level annotations using Self-supervised pre-training…

图像与视频处理 · 电气工程与系统科学 2023-06-29 Yoni Schirris , Efstratios Gavves , Iris Nederlof , Hugo Mark Horlings , Jonas Teuwen

Multimodal survival prediction, a crucial yet challenging task, demands the integration of multimodal medical data (\eg Whole Slide Images (WSIs) and Genomic Profiles) to achieve accurate prognostic modeling. Given the inherent…

计算机视觉与模式识别 · 计算机科学 2026-05-21 Huayi Wang , Haochao Ying , Yuyang Xu , Qiyao Zheng , jun wang , Cheng Zhang , Ying Sun , Jian Wu

Recent advancements in graph-based approaches for multiplexed immunofluorescence (mIF) images have significantly propelled the field forward, offering deeper insights into patient-level phenotyping. However, current graph-based…

计算机视觉与模式识别 · 计算机科学 2024-07-26 Sukwon Yun , Jie Peng , Alexandro E. Trevino , Chanyoung Park , Tianlong Chen

As the frontline data for cancer diagnosis, microscopic pathology images are fundamental for providing patients with rapid and accurate treatment. However, despite their practical value, the deep learning community has largely overlooked…

计算机视觉与模式识别 · 计算机科学 2025-06-23 Sungrae Hong , Hyeongmin Park , Youngsin Ko , Sol Lee , Bryan Wong , Mun Yong Yi

Increased levels of tumor infiltrating lymphocytes (TILs) in cancer tissue indicate favourable outcomes in many types of cancer. Manual quantification of immune cells is inaccurate and time consuming for pathologists. Our aim is to leverage…

This paper presents a comprehensive study focused on disentangling hippocampal shape variations from diffusion tensor imaging (DTI) datasets within the context of neurological disorders. Leveraging a Mesh Variational Autoencoder (VAE)…

计算机视觉与模式识别 · 计算机科学 2024-11-12 Jakaria Rabbi , Johannes Kiechle , Christian Beaulieu , Nilanjan Ray , Dana Cobzas

Immunohistochemistry (IHC) biomarkers are essential tools for reliable cancer diagnosis and subtyping. It requires cross-staining comparison among Whole Slide Images (WSIs) of IHCs and hematoxylin and eosin (H&E) slides. Currently,…

图像与视频处理 · 电气工程与系统科学 2023-12-27 Abubakr Shafique , Morteza Babaie , Ricardo Gonzalez , Adrian Batten , Soma Sikdar , H. R. Tizhoosh

Multi-modal medical image fusion (MMIF) is increasingly recognized as an essential technique for enhancing diagnostic precision and facilitating effective clinical decision-making within computer-aided diagnosis systems. MMIF combines data…

图像与视频处理 · 电气工程与系统科学 2025-05-22 Muhammad Zubair , Muzammil Hussai , Mousa Ahmad Al-Bashrawi , Malika Bendechache , Muhammad Owais

Turbulent space and astrophysical plasmas exhibit a complex dynamics, which involves nonlinear coupling across different temporal and spatial scales. There is growing evidence that impulsive events, such as magnetic reconnection…

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

计算机视觉与模式识别 · 计算机科学 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

计算机视觉与模式识别 · 计算机科学 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

Multi-exposure image fusion (MEF) has emerged as a prominent solution to address the limitations of digital imaging in representing varied exposure levels. Despite its advancements, the field grapples with challenges, notably the reliance…

计算机视觉与模式识别 · 计算机科学 2023-09-06 Guanyao Wu , Hongming Fu , Jinyuan Liu , Long Ma , Xin Fan , Risheng Liu

The deep neural network is a research hotspot for histopathological image analysis, which can improve the efficiency and accuracy of diagnosis for pathologists or be used for disease screening. The whole slide pathological image can reach…

图像与视频处理 · 电气工程与系统科学 2022-05-09 Tingting Zheng , Weixing chen , Shuqin Li , Hao Quan , Qun Bai , Tianhang Nan , Song Zheng , Xinghua Gao , Yue Zhao , Xiaoyu Cui

Artificial intelligence-enabled histopathological data analysis has become a valuable assistant to the pathologist. However, existing models lack representation and inference abilities compared with those of pathologists, especially in…

计算机视觉与模式识别 · 计算机科学 2023-04-20 Bo Yu , Hechang Chen , Yunke Zhang , Lele Cong , Shuchao Pang , Hongren Zhou , Ziye Wang , Xianling Cong

Accurate classification of pediatric central nervous system tumors remains challenging due to histological complexity and limited training data. While pathology foundation models have advanced whole-slide image (WSI) analysis, they often…

Pathology images of histopathology can be acquired from camera-mounted microscopes or whole slide scanners. Utilizing similarity calculations to match patients based on these images holds significant potential in research and clinical…

图像与视频处理 · 电气工程与系统科学 2024-03-25 H. R. Tizhoosh , Liron Pantanowitz

Mitotic figure (MF) detection in histopathology images is challenging due to large variations in slide scanners, staining protocols, tissue types, and the presence of artifacts. This paper presents a collection of training techniques - a…

计算机视觉与模式识别 · 计算机科学 2025-08-28 Christian Marzahl , Brian Napora

Immunohistochemical (IHC) staining provides crucial molecular characterization of tissue samples and plays an indispensable role in the clinical examination and diagnosis of cancers. However, compared with the commonly used Hematoxylin and…

计算机视觉与模式识别 · 计算机科学 2026-01-07 Mingzhou Jiang , Jiaying Zhou , Nan Zeng , Mickael Li , Qijie Tang , Chao He , Huazhu Fu , Honghui He

In the field of computational histopathology, both whole slide images (WSIs) and diagnostic captions provide valuable insights for making diagnostic decisions. However, aligning WSIs with diagnostic captions presents a significant…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Qifeng Zhou , Wenliang Zhong , Yuzhi Guo , Michael Xiao , Hehuan Ma , Junzhou Huang