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Influenza occurs every season and occasionally causes pandemics. Despite its low mortality rate, influenza is a major public health concern, as it can be complicated by severe diseases like pneumonia. A fast, accurate and low-cost method to…

定量方法 · 定量生物学 2022-08-01 Yanhua Xu , Dominik Wojtczak

Influenza viruses mutate rapidly and can pose a threat to public health, especially to those in vulnerable groups. Throughout history, influenza A viruses have caused pandemics between different species. It is important to identify the…

机器学习 · 计算机科学 2024-05-24 Yanhua Xu , Dominik Wojtczak

The Influenza type A virus can be considered as one of the most severe viruses that can infect multiple species with often fatal consequences to the hosts. The Haemagglutinin (HA) gene of the virus has the potential to be a target for…

定量方法 · 定量生物学 2021-02-16 Charalambos Chrysostomou , Harris Partaourides , Huseyin Seker

The Influenza virus can be considered as one of the most severe viruses that can infect multiple species with often fatal consequences to the hosts. The Hemagglutinin (HA) gene of the virus can be a target for antiviral drug development…

定量方法 · 定量生物学 2021-08-11 Charalambos Chrysostomou , Floris Alexandrou , Mihalis A. Nicolaou , Huseyin Seker

Influenza is an infectious disease with the potential to become a pandemic, and hence, forecasting its prevalence is an important undertaking for planning an effective response. Research has found that web search activity can be used to…

机器学习 · 计算机科学 2021-05-27 Michael Morris , Peter Hayes , Ingemar J. Cox , Vasileios Lampos

Public health surveillance systems often fail to detect emerging infectious diseases, particularly in resource limited settings. By integrating relevant clinical and internet-source data, we can close critical gaps in coverage and…

应用统计 · 统计学 2019-03-05 Kai Liu , Ravi Srinivasan , Lauren Ancel Meyers

Infectious diseases pose significant human and economic burdens. Accurately forecasting disease incidence can enable public health agencies to respond effectively to existing or emerging diseases. Despite progress in the field, developing…

机器学习 · 计算机科学 2024-09-04 Michael Morris

The Influenza A virus belongs to the Orthomyxoviridae family. Influenza virus infection occurs yearly in all countries of the world. It usually kills between 250,000 and 500,000 people and causes severe illness in millions more. Over the…

细胞行为 · 定量生物学 2014-11-25 Juliana Silva Capitanio , Richard W. Wozniak

Accurate epidemic forecasting is critical for informing public health decisions and timely interventions. While Physics-Informed Neural Networks have shown promise in various scientific domains, their potential application to real-time…

物理与社会 · 物理学 2026-05-20 Martina Rama , Gabriele Santin , Giulia Cencetti , Michele Tizzoni , Bruno Lepri

The influenza virus hemagglutinin is an important part of the virus attachment to the host cells. The hemagglutinin proteins are one of the genetic regions of the virus with a high potential for mutations. Due to the importance of…

The accurate forecasting of infectious epidemic diseases such as influenza is a crucial task undertaken by medical institutions. Although numerous flu forecasting methods and models based mainly on historical flu activity data and online…

机器学习 · 计算机科学 2021-07-08 Taichi Murayama , Shoko Wakamiya , Eiji Aramaki

A central challenge in every field of biology is to use existing measurements to predict the outcomes of future experiments. In this work, we consider the wealth of antibody inhibition data against variants of the influenza virus. Due to…

定量方法 · 定量生物学 2023-07-27 Tal Einav , Rong Ma

Determining phenotype from genetic data is a fundamental challenge. Influenza A viruses undergo rapid antigenic drift and identification of emerging antigenic variants is critical to the vaccine selection process. Using former seasonal…

Influenza, an infectious disease, causes many deaths worldwide. Predicting influenza victims during epidemics is an important task for clinical, hospital, and community outbreak preparation. On-line user-generated contents (UGC), primarily…

计算机与社会 · 计算机科学 2021-04-15 Taichi Murayama , Nobuyuki Shimizu , Sumio Fujita , Shoko Wakamiya , Eiji Aramaki

Language models have advanced sequence analysis, yet DNA foundation models often lag behind task-specific methods for unclear reasons. We present AntigenLM, a generative DNA language model pretrained on influenza genomes with intact,…

基因组学 · 定量生物学 2026-02-12 Yue Pei , Xuebin Chi , Yu Kang

Predicting cross-immunity between viral strains is vital for public health surveillance and vaccine development. Traditional neural network methods, such as BiLSTM, could be ineffective due to the lack of lab data for model training and the…

计算工程、金融与科学 · 计算机科学 2023-10-18 Yiming Du , Zhuotian Li , Qian He , Thomas Wetere Tulu , Kei Hang Katie Chan , Lin Wang , Sen Pei , Zhanwei Du , Xiao-Ke Xu , Xiao Fan Liu

Avian Influenza breakouts cause millions of dollars in damage each year globally, especially in Asian countries such as China and South Korea. The impact magnitude of a breakout directly correlates to time required to fully understand the…

定量方法 · 定量生物学 2018-02-27 Woo Yong Choi , Kyu Ye Song , Chan Woo Lee

The ability to predict the evolution of a pathogen would significantly improve the ability to control, prevent, and treat disease. Despite significant progress in other problem spaces, deep learning has yet to contribute to the issue of…

定量方法 · 定量生物学 2020-08-28 Daniel S. Berman , Craig Howser , Thomas Mehoke , Jared D. Evans

Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade host immunity acquired to previous virus strains. Antigenic phenotype is often assessed through pairwise measurement of cross-reactivity between…

In the research, we developed a computer vision solution to support diagnostic radiology in differentiating between COVID-19 pneumonia, influenza virus pneumonia, and normal biomarkers. The chest radiograph appearance of COVID-19 pneumonia…

图像与视频处理 · 电气工程与系统科学 2021-12-15 Julianna Antonchuk , Benjamin Prescott , Philip Melanchthon , Robin Singh
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