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Gene expression is inherently noisy, posing a challenge to understanding how precise and reproducible patterns of gene expression emerge in mammals. We investigate this phenomenon using gastruloids, an in vitro model for early mammalian…

细胞行为 · 定量生物学 2025-11-19 Melody Merle , Leah Friedman , Corinne Chureau , Armin Shoushtarizadeh , Thomas Gregor

Cellular automata are a discrete dynamical system which models massively parallel computation. Much attention is devoted to computations with small time complexity for which the parallelism may provide further possibilities. In this paper,…

形式语言与自动机理论 · 计算机科学 2012-08-15 Anaël Grandjean , Gaétan Richard , Véronique Terrier

Many patterns in nature exhibit self-similarity: they can be compactly described via self-referential transformations. Said patterns commonly appear in natural and artificial objects, such as molecules, shorelines, galaxies and even images.…

机器学习 · 计算机科学 2022-04-19 Michael Poli , Winnie Xu , Stefano Massaroli , Chenlin Meng , Kuno Kim , Stefano Ermon

We report experimental extensions of Lenia, a continuous cellular automata family capable of producing lifelike self-organizing autonomous patterns. The rule of Lenia was generalized into higher dimensions, multiple kernels, and multiple…

元胞自动机与格子气 · 物理学 2021-07-12 Bert Wang-Chak Chan

The recent successes of deep learning and deep reinforcement learning have firmly established their statuses as state-of-the-art artificial learning techniques. However, longstanding drawbacks of these approaches, such as their poor sample…

人工智能 · 计算机科学 2020-02-05 Thommen George Karimpanal

Characterization of pluripotent states, in which cells can both self-renew and differentiate, and the irreversible loss of pluripotency are important research areas in developmental biology. In particular, an understanding of these…

分子网络 · 定量生物学 2015-09-02 Tadashi Miyamoto , Chikara Furusawa , Kunihiko Kaneko

In this paper we study the space evolution in the Rule 54 reversible cellular automaton, which is a paradigmatic example of a deterministic interacting lattice gas. We show that the spatial translation of time configurations of the…

统计力学 · 物理学 2020-08-20 Katja Klobas , Tomaž Prosen

To learn about the past from a sample of genomic sequences, one needs to understand how evolutionary processes shape genetic diversity. Most population genetic inference is based on frameworks assuming adaptive evolution is rare. But if…

种群与进化 · 定量生物学 2014-03-25 Richard A. Neher

Neural Cellular Automata (NCAs) are a promising new approach to model self-organizing processes, with potential applications in life science. However, their deterministic nature limits their ability to capture the stochasticity of…

人工智能 · 计算机科学 2025-06-26 Salvatore Milite , Giulio Caravagna , Andrea Sottoriva

The Game of Life (GoL), one well known 2D cellular automaton, does not typically ensure interesting long-term phenotypic dynamics. Therefore, while being Turing complete, GoL cannot be said to be open-ended. In this work, we extend GoL with…

元胞自动机与格子气 · 物理学 2024-06-21 Aarati Shrestha , Felix Reimers , Sanyam Jain , Paolo Baldini , Michele Braccini , Andrea Roli , Stefano Nichele

In contrast to deep reinforcement learning agents, biological neural networks are grown through a self-organized developmental process. Here we propose a new hypernetwork approach to grow artificial neural networks based on neural cellular…

神经与进化计算 · 计算机科学 2022-04-26 Elias Najarro , Shyam Sudhakaran , Claire Glanois , Sebastian Risi

This study introduces EngramNCA, a neural cellular automaton (NCA) that integrates both publicly visible states and private, cell-internal memory channels, drawing inspiration from emerging biological evidence suggesting that memory storage…

神经与进化计算 · 计算机科学 2025-04-17 Etienne Guichard , Felix Reimers , Mia Kvalsund , Mikkel Lepperød , Stefano Nichele

Background: The evolution of microRNA regulation in metazoans is a mysterious process: MicroRNA sequences are highly conserved among distal organisms, but on the other hand, there is no evident conservation of their targets. Results: We…

分子网络 · 定量生物学 2008-02-27 Yonatan Bilu

Evolutionary transitions occur when previously-independent replicating entities unite to form more complex individuals. Such transitions have profoundly shaped natural evolutionary history and occur in two forms: fraternal transitions…

种群与进化 · 定量生物学 2023-10-10 Matthew Andres Moreno , Charles Ofria

Neural codes appear efficient. Naturally, neuroscientists contend that an efficient process is responsible for generating efficient codes. They argue that natural selection is the efficient process that generates those codes. Although…

神经元与认知 · 定量生物学 2022-03-21 Han Kim

Cellular automata (CA) consist of an array of identical cells, each of which may take one of a finite number of possible states. The entire array evolves in discrete time steps by iterating a global evolution G. Further, this global…

离散数学 · 计算机科学 2015-03-18 Pablo Arrighi , Renan Fargetton , Vincent Nesme , Eric Thierry

Populations of replicating entities frequently experience sudden or cyclical changes in environment. We explore the implications of this phenomenon via a environmental switching parameter in several common evolutionary dynamics models…

动力系统 · 数学 2013-06-12 Marc Harper , Dashiell Fryer , Andrew Vlasic

Continual learning has become a trending topic in machine learning. Recent studies have discovered an interesting phenomenon called loss of plasticity, referring to neural networks gradually losing the ability to learn new tasks. However,…

机器学习 · 计算机科学 2026-02-11 Tianhui Liu , Lili Mou

The search for neural architecture is producing many of the most exciting results in artificial intelligence. It has increasingly become apparent that task-specific neural architecture plays a crucial role for effectively solving problems.…

神经与进化计算 · 计算机科学 2021-03-30 Samuel Schmidgall

Heralded by the initial success in speech recognition and image classification, learning-based approaches with neural networks, commonly referred to as deep learning, have spread across various fields. A primitive form of a neural network…

机器人学 · 计算机科学 2024-09-02 Takuma Yoneda
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