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Genome organization in eukaryotes during interphase stems from the delicate balance between non-random correlations present in the DNA polynucleotide linear sequence and the physico/chemical reactions which shape continuously the form and…

基因组学 · 定量生物学 2020-05-15 Alessandra Merlotti , Angelo Rosa , Daniel Remondini

Artificial intelligence for scientific discovery has recently generated significant interest within the machine learning and scientific communities, particularly in the domains of chemistry, biology, and material discovery. For these…

3D scene generation seeks to synthesize spatially structured, semantically meaningful, and photorealistic environments for applications such as immersive media, robotics, autonomous driving, and embodied AI. Early methods based on…

计算机视觉与模式识别 · 计算机科学 2025-05-09 Beichen Wen , Haozhe Xie , Zhaoxi Chen , Fangzhou Hong , Ziwei Liu

The coding space of protein sequences is shaped by evolutionary constraints set by requirements of function and stability. We show that the coding space of a given protein family--the total number of sequences in that family--can be…

生物大分子 · 定量生物学 2020-11-20 Jacopo Marchi , Ezequiel A. Galpern , Rocio Espada , Diego U. Ferreiro , Aleksandra M. Walczak , Thierry Mora

We introduce an approach for analyzing the variation of features generated by convolutional neural networks (CNNs) with respect to scene factors that occur in natural images. Such factors may include object style, 3D viewpoint, color, and…

计算机视觉与模式识别 · 计算机科学 2015-06-04 Mathieu Aubry , Bryan Russell

Due to the availability of large-scale skeleton datasets, 3D human action recognition has recently called the attention of computer vision community. Many works have focused on encoding skeleton data as skeleton image representations based…

计算机视觉与模式识别 · 计算机科学 2019-07-31 Carlos Caetano , Jessica Sena , François Brémond , Jefersson A. dos Santos , William Robson Schwartz

Coherent diffraction imaging enables the imaging of individual defects, such as dislocations or stacking faults, in materials.These defects and their surrounding elastic strain fields have a critical influence on the macroscopic properties…

In this study, the distributions of protein structure classes (or folding types) of experimentally determined structures from a legacy dataset and a comprehensive database (SCOP) are modeled precisely with geometric constructs such as…

生物大分子 · 定量生物学 2025-10-21 Boryeu Mao

The flawless functioning of a protein is essentially linked to its own three-dimensional structure. Therefore, the prediction of a protein structure from its amino acid sequence is a fundamental problem in many fields that draws researchers…

神经与进化计算 · 计算机科学 2019-07-10 Nabil Boumedine , Sadek Bouroubi

In the search for neutrinoless double-beta decay, the high-pressure gaseous Time Projection Chamber has a distinct advantage, because the ionization charge tracks produced by particle interactions are extended and the detector captures the…

数据分析、统计与概率 · 物理学 2018-09-10 Pengcheng Ai , Dong Wang , Guangming Huang , Xiangming Sun

The surrounding world surprises us by the beauty and variety of complex shapes that emerge from nanometric to macroscopic scales. Natural or manufactured materials (sandstones, sedimentary rocks and cement), colloidal solutions (proteins…

数学物理 · 物理学 2009-09-10 Denis Grebenkov

Matrix concentration inequalities and their recently discovered sharp counterparts provide powerful tools to bound the spectrum of random matrices whose entries are linear functions of independent random variables. However, in many…

Molecular shape and geometry dictate key biophysical recognition processes, yet many graph neural networks disregard 3D information for molecular property prediction. Here, we propose a new contrastive-learning procedure for graph neural…

Applications of Discrete Fracture Network (DFN) modeling are becoming increasingly prevalent in engineering analyses involving fractured rock masses. For example, kinematic evaluations of slope or underground excavation stability and the…

地球物理 · 物理学 2017-11-16 Younes Fadakar Alghalandis , Davide Elmo , Erik Eberhardt

In this paper we address the task of the comparison and the classification of 3D shape sequences of human. The non-linear dynamics of the human motion and the changing of the surface parametrization over the time make this task very…

计算机视觉与模式识别 · 计算机科学 2022-07-27 Emery Pierson , Mohamed Daoudi , Sylvain Arguillere

It is known since the early days of molecular biology that proteins locate their specific targets on DNA up to two orders of magnitude faster than the Smoluchowski 3D diffusion rate. It was the idea due to Delbruck that they are…

生物大分子 · 定量生物学 2015-06-26 Tao Hu , A. Yu. Grosberg , B. I. Shklovskii

Most existing 3D assembly methods treat the problem as pure pose estimation, rearranging observed parts via rigid transformations. In contrast, human assembly naturally couples structural reasoning with holistic shape inference. Inspired by…

计算机视觉与模式识别 · 计算机科学 2026-02-27 Zeyu Jiang , Sihang Li , Siqi Tan , Chenyang Xu , Juexiao Zhang , Julia Galway-Witham , Xue Wang , Scott A. Williams , Radu Iovita , Chen Feng , Jing Zhang

Interactive molecular graphics applications facilitate analysis of three dimensional protein structures. Naturally, non-interactive 2-D snapshots of the protein structures do not convey the same level of geometric detail. Several 2-D…

定量方法 · 定量生物学 2014-02-24 Francis Bell , Chunyu Zhao , Ahmet Sacan

The spatial distribution of DNA base sequence A, C, G and T exhibit selfsimilar fractal fluctuations and the corresponding power spectra follow inverse power law form, which implies the following: (1) A scale invariant eddy continuum,…

综合物理 · 物理学 2007-05-23 A. M. Selvam

We have presented the basic knowledge on the structure of molecules coding the genetic information, mechanisms of transfer of this information from DNA to proteins and phenomena connected with replication of DNA. In particular, we have…

基因组学 · 定量生物学 2009-09-30 Dorota Mackiewicz , Stanislaw Cebrat