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Focal Cortical Dysplasia (FCD) is a primary cause of drug-resistant epilepsy and is difficult to detect in brain {magnetic resonance imaging} (MRI) due to the subtle and small-scale nature of its lesions. Accurate segmentation of FCD…

图像与视频处理 · 电气工程与系统科学 2025-10-09 Mehdi Rabiee , Sergio Greco , Reza Shahbazian , Irina Trubitsyna

As populations age, the rise of multimorbidity poses a significant healthcare challenge. However, our ability to quantitatively forecast the progression of multimorbidity remains limited. Leveraging a nationwide dataset comprising…

物理与社会 · 物理学 2025-07-29 Katharina Ledebur , Alexandra Kautzky-Willer , Stefan Thurner , Peter Klimek

BACKGROUND: An important goal of chronic obstructive pulmonary disease (COPD) treatment is to reduce the frequency of exacerbations. Some observations suggest a decline in exacerbation rates in clinical trials over time. A more systematic…

应用统计 · 统计学 2019-08-20 Stefan Andreas , Christian Röver , Judith Heinz , Sebastian Straube , Henrik Watz , Tim Friede

Modelling deformation of anatomical objects observed in medical images can help describe disease progression patterns and variations in anatomy across populations. We apply a stochastic generalisation of the Large Deformation Diffeomorphic…

统计理论 · 数学 2018-12-14 Line Kühnel , Alexis Arnaudon , Tom Fletcher , Stefan Sommer

Federated- and Continual Learning have been established as approaches to enable privacy-aware learning on continuously changing data, as required for deploying AI systems in histopathology images. However, data shifts can occur in a dynamic…

机器学习 · 计算机科学 2025-01-09 Niklas Babendererde , Haozhe Zhu , Moritz Fuchs , Jonathan Stieber , Anirban Mukhopadhyay

Delineation of anatomical structures is often the first step of many medical image analysis workflows. While convolutional neural networks achieve high performance, these do not incorporate anatomical shape information. We introduce a novel…

图像与视频处理 · 电气工程与系统科学 2023-10-18 Athira J Jacob , Puneet Sharma , Daniel Ruckert

We applied deep learning to create an algorithm for breathing phase detection in lung sound recordings, and we compared the breathing phases detected by the algorithm and manually annotated by two experienced lung sound researchers. Our…

计算机视觉与模式识别 · 计算机科学 2019-04-18 Cristina Jácome , Johan Ravn , Einar Holsbø , Juan Carlos Aviles-Solis , Hasse Melbye , Lars Ailo Bongo

Objective: Lung cancer is a leading cause of cancer-related mortality worldwide, primarily due to delayed diagnosis and poor early detection. This study aims to develop a computer-aided diagnosis (CAD) system that leverages large…

图像与视频处理 · 电气工程与系统科学 2025-09-16 Hafza Eman , Furqan Shaukat , Muhammad Hamza Zafar , Syed Muhammad Anwar

Parkinson's disease (PD) is a common and complex neurodegenerative disorder with 5 stages in the Hoehn and Yahr scaling. Given the heterogeneity of PD, it is challenging to classify early stages 1 and 2 and detect brain function…

神经元与认知 · 定量生物学 2022-07-22 Xueqi Guo , Sule Tinaz , Nicha C. Dvornek

An important paradigm in smart health is developing diagnosis tools and monitoring a patient's heart activity through processing Electrocardiogram (ECG) signals is a key example, sue to high mortality rate of heart-related disease. However,…

信号处理 · 电气工程与系统科学 2018-11-02 Jiaming Chen , Ali Valehi , Abolfazl Razi

Blood Pressure (BP) is one of the four primary vital signs indicating the status of the body's vital (life-sustaining) functions. BP is difficult to continuously monitor using a sphygmomanometer (i.e. a blood pressure cuff), especially in…

机器学习 · 计算机科学 2021-08-03 Ali Tazarv , Marco Levorato

Fractional flow reserve (FFR) is the gold standard for diagnosing coronary artery disease (CAD). FFRCT uses computational fluid dynamics (CFD) to evaluate FFR non-invasively by simulating coronary flow in geometries reconstructed from…

Parkinson's disease is a neurological condition that occurs in nearly 1% of the world's population. The disease is manifested by a drop in dopamine production, symptoms are cognitive and behavioural and include a wide range of personality…

图像与视频处理 · 电气工程与系统科学 2024-01-08 Maria Frasca , Davide La Torre , Gabriella Pravettoni , Ilaria Cutica

Since the breakout of coronavirus disease (COVID-19), the computer-aided diagnosis has become a necessity to prevent the spread of the virus. Detecting COVID-19 at an early stage is essential to reduce the mortality risk of the patients. In…

The COVID-19 pandemic has presented unprecedented challenges worldwide, necessitating effective modelling approaches to understand and control its transmission dynamics. In this study, we propose a novel approach that integrates…

种群与进化 · 定量生物学 2025-01-14 Moein Khalighi , Leo Lahti , Faïçal Ndaïrou , Peter Rashkov , Delfim F. M. Torres

This work presents an algorithm for determining the parameters of a nonlinear dynamic model of the respiratory system in patients undergoing assisted ventilation. Using the pressure and flow signals measured at the mouth, the model's…

系统与控制 · 电气工程与系统科学 2024-03-01 Diego A. Riva , Carolina A. Evangelista , Paul F. Puleston , Luis Corsiglia , Nahuel Dargains

Background. Clinical parameters measured from gated single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI) have value in predicting cardiac resynchronization therapy (CRT) patient outcomes, but still show…

计算机视觉与模式识别 · 计算机科学 2023-12-27 Kristoffer Larsena , Zhuo He , Chen Zhao , Xinwei Zhang , Quiying Sha , Claudio T Mesquitad , Diana Paeze , Ernest V. Garciaf , Jiangang Zou , Amalia Peix , Weihua Zhou

In this paper, a new fractional order generalization of the classical Windkessel arterial model is developed to describe the aortic input impedance as an assessment of the left ventricular after-load. The proposed models embeds…

组织与器官 · 定量生物学 2019-08-15 Mohamed A. Bahloul , Taous-Meriem Laleg Kirati

A Caputo-type fractional-order mathematical model for "metapopulation cholera transmission" was recently proposed in [Chaos Solitons Fractals 117 (2018), 37--49]. A sensitivity analysis of that model is done here to show the accuracy…

最优化与控制 · 数学 2021-12-08 Silverio Rosa , Delfim F. M. Torres

This paper introduces the Parsimonious Dynamic Mode Decomposition (parsDMD), a novel algorithm designed to automatically select an optimally sparse subset of dynamic modes for both spatiotemporal and purely temporal data. By incorporating…

统计方法学 · 统计学 2024-12-02 Arpan Das , Pier Marzocca , Oleg Levinski