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Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Developing computational tools for integrative analysis across multiple types of omics data has been of immense importance in cancer molecular biology and precision medicine research. While recent advancements have yielded integrative…

Computer-assisted diagnostic and prognostic systems of the future should be capable of simultaneously processing multimodal data. Multimodal deep learning (MDL), which involves the integration of multiple sources of data, such as images and…

计算机视觉与模式识别 · 计算机科学 2023-10-20 Zhaoyi Sun , Mingquan Lin , Qingqing Zhu , Qianqian Xie , Fei Wang , Zhiyong Lu , Yifan Peng

Deep learning models have had a great success in disease classifications using large data pools of skin cancer images or lung X-rays. However, data scarcity has been the roadblock of applying deep learning models directly on prostate…

Multi-omics data is increasingly being utilized to advance computational methods for cancer classification. However, multi-omics data integration poses significant challenges due to the high dimensionality, data complexity, and distinct…

基因组学 · 定量生物学 2024-10-10 Fadi Alharbi , Aleksandar Vakanski , Boyu Zhang , Murtada K. Elbashir , Mohanad Mohammed

Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

图像与视频处理 · 电气工程与系统科学 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

Oral cancer presents a formidable challenge in oncology, necessitating early diagnosis and accurate prognosis to enhance patient survival rates. Recent advancements in machine learning and data mining have revolutionized traditional…

机器学习 · 计算机科学 2025-06-13 Mohammad Subhi Al-Batah , Muhyeeddin Alqaraleh , Mowafaq Salem Alzboon

A key challenge in learning from multimodal biological data is missing modalities, where data from one or more modalities are absent for some patients. Existing approaches either exclude patients with missing modalities, impute missing…

机器学习 · 计算机科学 2026-05-19 Sina Tabakhi , Chen , Chen , Haiping Lu

Early detection is crucial for successful cancer treatment and increasing survivability rates, particularly in the most common forms. Ten different cancers have been identified in most of these advances that effectively use CNNs…

计算机视觉与模式识别 · 计算机科学 2026-05-15 Hossein Molaeian , Kaveh Karamjani , Sina Teimouri , Saeed Roshani , Sobhan Roshani

Genomics, especially multi-omics, has made precision medicine feasible. The completion and publicly accessible multi-omics resource with clinical outcome, such as The Cancer Genome Atlas (TCGA) is a great test bed for developing…

基因组学 · 定量生物学 2020-08-31 Lana X Garmire

Mechanistic learning, the synergistic combination of knowledge-driven and data-driven modeling, is an emerging field. In particular, in mathematical oncology, the application of mathematical modeling to cancer biology and oncology, the use…

定量方法 · 定量生物学 2023-12-13 John Metzcar , Catherine R. Jutzeler , Paul Macklin , Alvaro Köhn-Luque , Sarah C. Brüningk

Phyllodes tumors (PTs) are rare fibroepithelial breast lesions that are difficult to classify preoperatively due to their radiological similarity to benign fibroadenomas. This often leads to unnecessary surgical excisions. To address this,…

计算机视觉与模式识别 · 计算机科学 2025-09-26 Farhan Fuad Abir , Abigail Elliott Daly , Kyle Anderman , Tolga Ozmen , Laura J. Brattain

In this work, we propose a multi-modal Convolutional Neural Network (CNN) approach for brain tumor segmentation. We investigate how to combine different modalities efficiently in the CNN framework.We adapt various fusion methods, which are…

计算机视觉与模式识别 · 计算机科学 2018-09-21 Mehmet Aygün , Yusuf Hüseyin Şahin , Gözde Ünal

Cancer is a complex genetic disease involving uncontrolled cell growth and proliferation, and necessitates effective targeting of dysregulated cellular pathways underlying cancer progression. Multiple genetic and epigenetic alterations…

其他定量生物学 · 定量生物学 2026-01-28 Manish Kumar

Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…

图像与视频处理 · 电气工程与系统科学 2022-10-18 Yuzhe Lu , Adam Perer

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

图像与视频处理 · 电气工程与系统科学 2020-10-07 Marvin Lerousseau , Eric Deutsh , Nikos Paragios

This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…

图像与视频处理 · 电气工程与系统科学 2024-03-01 Ha Anh Vu

Multimodal medical image fusion is a crucial task that combines complementary information from different imaging modalities into a unified representation, thereby enhancing diagnostic accuracy and treatment planning. While deep learning…

图像与视频处理 · 电气工程与系统科学 2024-11-19 Meng Zhou , Yuxuan Zhang , Xiaolan Xu , Jiayi Wang , Farzad Khalvati

There is an increasing interest in the use of Deep Learning (DL) based methods as a supporting analytical framework in oncology. However, most direct applications of DL will deliver models with limited transparency and explainability, which…

定量方法 · 定量生物学 2023-01-26 Magdalena Wysocka , Oskar Wysocki , Marie Zufferey , Dónal Landers , André Freitas

Clinical diagnostic and treatment decisions rely upon the integration of patient-specific data with clinical reasoning. Cancer presents a unique context that influence treatment decisions, given its diverse forms of disease evolution.…

图像与视频处理 · 电气工程与系统科学 2022-12-23 K. Ruwani M. Fernando , Chris P. Tsokos