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Due to cellular heterogeneity, cell nuclei classification, segmentation, and detection from pathological images are challenging tasks. In the last few years, Deep Convolutional Neural Networks (DCNN) approaches have been shown…

计算机视觉与模式识别 · 计算机科学 2018-11-09 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

定量方法 · 定量生物学 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

Accurate prognosis for an individual patient is a key component of precision oncology. Recent advances in machine learning have enabled the development of models using a wider range of data, including imaging. Radiomics aims to extract…

Every year millions of people die due to disease of Cancer. Due to its invasive nature it is very complex to cure even in primary stages. Hence, only method to survive this disease completely is via forecasting by analyzing the early…

计算机视觉与模式识别 · 计算机科学 2018-08-24 Shivam Singh , Stuti Pathak

Automating tissue segmentation and tumor detection in histopathology images of colorectal cancer (CRC) is an enabler for faster diagnostic pathology workflows. At the same time it is a challenging task due to low availability of public…

图像与视频处理 · 电气工程与系统科学 2023-04-07 Lydia A. Schoenpflug , Maxime W. Lafarge , Anja L. Frei , Viktor H. Koelzer

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

定量方法 · 定量生物学 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

There exists unexplained diverse variation within the predefined colon cancer stages using only features either from genomics or histopathological whole slide images as prognostic factors. Unraveling this variation will bring about improved…

定量方法 · 定量生物学 2022-12-15 Olalekan Ogundipe , Zeyneb Kurt , Wai Lok Woo

Automatic nuclei segmentation and classification play a vital role in digital pathology. However, previous works are mostly built on data with limited diversity and small sizes, making the results questionable or misleading in actual…

图像与视频处理 · 电气工程与系统科学 2023-05-31 Kai Yao , Kaizhu Huang , Jie Sun , Amir Hussain

Cancer is one of the leading causes of death in the developed world. Cancer diagnosis is performed through the microscopic analysis of a sample of suspicious tissue. This process is time consuming and error prone, but Deep Learning models…

图像与视频处理 · 电气工程与系统科学 2022-03-04 Pedro Costa , Yongpan Fu , João Nunes , Aurélio Campilho , Jaime S. Cardoso

Melanoma is the most lethal form of skin cancer, with an increasing incidence rate worldwide. Analyzing histological images of melanoma by localizing and classifying tissues and cell nuclei is considered the gold standard method for…

计算机视觉与模式识别 · 计算机科学 2025-09-03 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

The spectacular response observed in clinical trials of immunotherapy in patients with previously uncurable Melanoma, a highly aggressive form of skin cancer, calls for a better understanding of the cancer-immune interface. Computational…

计算机视觉与模式识别 · 计算机科学 2018-08-08 Konstantinos Zormpas-Petridis , Henrik Failmezger , Ioannis Roxanis , Matthew Blackledge , Yann Jamin , Yinyin Yuan

Nucleus detection in histopathology is pivotal for a wide range of clinical applications. Existing approaches either regress nuclear proxy maps that require complex post-processing, or employ dense anchors or queries that introduce severe…

计算机视觉与模式识别 · 计算机科学 2026-03-10 Zhongyi Shui , Honglin Li , Xiaozhong Ji , Ye Zhang , Zijiang Yang , Chenglu Zhu , Yuxuan Sun , Kai Yao , Conghui He , Cheng Tan

Pathology Foundation Models (FMs) have shown strong performance across a wide range of pathology image representation and diagnostic tasks. However, FMs do not exhibit the expected performance advantage over traditional specialized models…

计算机视觉与模式识别 · 计算机科学 2026-03-05 Zijiang Yang , Chen Kuang , Dongmei Fu

This paper reports the method and evaluation results of MedAusbild team for ISIC challenge task. Since early 2017, our team has worked on melanoma classification [1][6], and has employed deep learning since beginning of 2018 [7]. Deep…

机器学习 · 计算机科学 2018-07-25 Sara Nasiri , Matthias Jung , Julien Helsper , Madjid Fathi

Central nervous system (CNS) tumors come with the vastly heterogeneous histologic, molecular and radiographic landscape, rendering their precise characterization challenging. The rapidly growing fields of biophysical modeling and radiomics…

定量方法 · 定量生物学 2020-06-30 Andreas Mang , Spyridon Bakas , Shashank Subramanian , Christos Davatzikos , George Biros

Identify the cells' nuclei is the important point for most medical analyses. To assist doctors finding the accurate cell' nuclei location automatically is highly demanded in the clinical practice. Recently, fully convolutional neural…

计算机视觉与模式识别 · 计算机科学 2019-11-25 Tianyang Zhang , Rui Ma

Digital pathology is one of the most significant developments in modern medicine. Pathological examinations are the gold standard of medical protocols and play a fundamental role in diagnosis. Recently, with the advent of digital scanners,…

图像与视频处理 · 电气工程与系统科学 2021-12-09 Mahdi Arab Loodaricheh , Nader Karimi , Shadrokh Samavi

Cancer is one of the most life-threatening diseases worldwide, and head and neck (H&N) cancer is a prevalent type with hundreds of thousands of new cases recorded each year. Clinicians use medical imaging modalities such as computed…

图像与视频处理 · 电气工程与系统科学 2023-06-02 Ikboljon Sobirov

Gigapixel medical images provide massive data, both morphological textures and spatial information, to be mined. Due to the large data scale in histology, deep learning methods play an increasingly significant role as feature extractors.…

图像与视频处理 · 电气工程与系统科学 2022-06-16 Yiqing Shen , Bingxin Zhou , Xinye Xiong , Ruitian Gao , Yu Guang Wang

Nuclear segmentation is an important step for profiling aberrant regions of histology sections. However, segmentation is a complex problem as a result of variations in nuclear geometry (e.g., size, shape), nuclear type (e.g., epithelial,…

计算机视觉与模式识别 · 计算机科学 2018-02-16 Mina Khoshdeli , Bahram Parvin