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The size of nuclei in histological preparations from excised breast tumors is predictive of patient outcome (large nuclei indicate poor outcome). Pathologists take into account nuclear size when performing breast cancer grading. In…

计算机视觉与模式识别 · 计算机科学 2016-06-21 Mitko Veta , Paul J. van Diest , Josien P. W. Pluim

Early detection of pulmonary cancer is the most promising way to enhance a patient's chance for survival. Accurate pulmonary nodule detection in computed tomography (CT) images is a crucial step in diagnosing pulmonary cancer. In this…

计算机视觉与模式识别 · 计算机科学 2017-08-30 Jia Ding , Aoxue Li , Zhiqiang Hu , Liwei Wang

Skin cancer is the most common type of cancer. Specifically, melanoma is the cause of 75% of skin cancer deaths, although it is the least common skin cancer. Better detection of melanoma could have a positive impact on millions of people.…

计算机视觉与模式识别 · 计算机科学 2023-02-21 Chengdong Yao

We propose a novel weakly supervised method to improve the boundary of the 3D segmented nuclei utilizing an over-segmented image. This is motivated by the observation that current state-of-the-art deep learning methods do not result in…

计算机视觉与模式识别 · 计算机科学 2021-08-31 S. Shailja , Jiaxiang Jiang , B. S. Manjunath

The segmentation of cell nuclei in tissue images stained with the blood dye hematoxylin and eosin (H$\&$E) is essential for various clinical applications and analyses. Due to the complex characteristics of cellular morphology, a large…

图像与视频处理 · 电气工程与系统科学 2024-07-26 Ziwei Cui , Jingfeng Yao , Lunbin Zeng , Juan Yang , Wenyu Liu , Xinggang Wang

High-resolution microscopy images of tissue specimens provide detailed information about the morphology of normal and diseased tissue. Image analysis of tissue morphology can help cancer researchers develop a better understanding of cancer…

Cancer is a complex disease driven by dynamic regulatory shifts that cannot be fully captured by individual molecular profiling. We employ a data-driven approach to construct a coarse-grained dynamic network model based on hallmark…

定量方法 · 定量生物学 2025-02-28 Jiahe Wang , Yan Wu , Yuke Hou , Yang Li , Dachuan Xu , Changjing Zhuge , Yue Han

Treatment approaches for colorectal cancer (CRC) are highly dependent on the molecular subtype, as immunotherapy has shown efficacy in cases with microsatellite instability (MSI) but is ineffective for the microsatellite stable (MSS)…

计算机视觉与模式识别 · 计算机科学 2024-11-13 Hadar Hezi , Matan Gelber , Alexander Balabanov , Yosef E. Maruvka , Moti Freiman

Positron Emission Tomography (PET) /Computed Tomography (CT) is crucial for diagnosing, managing, and planning treatment for various cancers. Developing reliable deep learning models for the segmentation of tumor lesions in PET/CT scans in…

图像与视频处理 · 电气工程与系统科学 2024-09-24 Tanya Chutani , Saikiran Bonthu , Pranab Samanta , Nitin Singhal

The 7-point checklist (7PCL) is a widely used diagnostic tool in dermoscopy for identifying malignant melanoma by assigning point values to seven specific attributes. However, the traditional 7PCL is limited to distinguishing between…

计算机视觉与模式识别 · 计算机科学 2025-09-11 Yuheng Wang , Tianze Yu , Jiayue Cai , Sunil Kalia , Harvey Lui , Z. Jane Wang , Tim K. Lee

This report summarises our method and validation results for the ISIC Challenge 2018 - Skin Lesion Analysis Towards Melanoma Detection - Task 1: Lesion Segmentation. We present a two-stage method for lesion segmentation with optimised…

计算机视觉与模式识别 · 计算机科学 2018-10-02 Chengyao Qian , Ting Liu , Hao Jiang , Zhe Wang , Pengfei Wang , Mingxin Guan , Biao Sun

The histological assessment of human tissue has emerged as the key challenge for detection and treatment of cancer. A plethora of different data sources ranging from tissue microarray data to gene expression, proteomics or metabolomics data…

计算机视觉与模式识别 · 计算机科学 2016-01-05 Thomas J. Fuchs , Joachim M. Buhmann

Precision medicine fundamentally aims to establish causality between dysregulated biochemical mechanisms and cancer subtypes. Omics-based cancer subtyping has emerged as a revolutionary approach, as different level of omics records the…

基因组学 · 定量生物学 2023-08-25 Ziwei Yang , Zheng Chen , Yasuko Matsubara , Yasushi Sakurai

The detection of mitotic figures from different scanners/sites remains an important topic of research, owing to its potential in assisting clinicians with tumour grading. The MItosis DOmain Generalization (MIDOG) challenge aims to test the…

计算机视觉与模式识别 · 计算机科学 2021-09-30 Mostafa Jahanifar , Adam Shephard , Neda Zamani Tajeddin , R. M. Saad Bashir , Mohsin Bilal , Syed Ali Khurram , Fayyaz Minhas , Nasir Rajpoot

Colorectal cancer (CRC) remains a leading cause of cancer-related deaths worldwide, with polyp removal being an effective early screening method. However, navigating the colon for thorough polyp detection poses significant challenges. To…

计算机视觉与模式识别 · 计算机科学 2024-12-23 Xinwei Ju , Rema Daher , Razvan Caramalau , Baoru Huang , Danail Stoyanov , Francisco Vasconcelos

The automated segmentation of cancer tissue in histopathology images can help clinicians to detect, diagnose, and analyze such disease. Different from other natural images used in many convolutional networks for benchmark, histopathology…

计算机视觉与模式识别 · 计算机科学 2021-08-06 Juan P. Vigueras-Guillén , Joan Lasenby , Frank Seeliger

Molecular subtypes of colorectal cancer (CRC) significantly influence treatment decisions. While convolutional neural networks (CNNs) have recently been introduced for automated CRC subtype identification using H&E stained histopathological…

计算机视觉与模式识别 · 计算机科学 2024-09-13 Hadar Hezi , Daniel Shats , Daniel Gurevich , Yosef E. Maruvka , Moti Freiman

Colorectal cancer (CRC) is one of the most common types of cancer with a high mortality rate. Colonoscopy is the preferred procedure for CRC screening and has proven to be effective in reducing CRC mortality. Thus, a reliable computer-aided…

计算机视觉与模式识别 · 计算机科学 2021-09-15 Kaidong Li , Mohammad I. Fathan , Krushi Patel , Tianxiao Zhang , Cuncong Zhong , Ajay Bansal , Amit Rastogi , Jean S. Wang , Guanghui Wang

This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…

图像与视频处理 · 电气工程与系统科学 2024-03-01 Ha Anh Vu

Biomarkers identify a patients response to treatment. With the recent advances in artificial intelligence based on the Transformer networks, there is only limited research has been done to measure the performance on challenging…

计算机视觉与模式识别 · 计算机科学 2022-06-24 Vivek Kumar Singh , Paul O Reilly , Jacqueline James , Manuel Salto Tellez , Perry Maxwell
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