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Deep generative models are increasingly becoming integral parts of the in silico molecule design pipeline and have dual goals of learning the chemical and structural features that render candidate molecules viable while also being flexible…

生物大分子 · 定量生物学 2021-06-08 Yair Schiff , Vijil Chenthamarakshan , Karthikeyan Natesan Ramamurthy , Payel Das

In this paper, a systematic approach is developed to embed the dynamical description of a nonlinear system into a linear parameter-varying (LPV) system representation. Initially, the nonlinear functions in the model representation are…

系统与控制 · 电气工程与系统科学 2020-11-09 Arash Sadeghzadeh , Roland Toth

We developed a single factor model with measure-specific sample weights for multivariate data with multiple observed indicators clustered within a higher level subject. The factor is therefore a latent variable shared by multiple indicators…

统计方法学 · 统计学 2019-10-22 Chengan Du , Shu-Xia Li , Zhenqiu Lin , Haiqun Lin

Latent variable models are powerful statistical tools that can uncover relevant variation between patients or cells, by inferring unobserved hidden states from observable high-dimensional data. A major shortcoming of current methods,…

机器学习 · 统计学 2022-04-12 Arber Qoku , Florian Buettner

Temperature-induced phase transition in BaTiO3 has been explored using the machine learning analysis of domain morphologies visualized via variable-temperature scanning transmission electron microscopy (STEM) imaging data. This approach is…

材料科学 · 物理学 2020-11-20 Mani Valleti , Reinis Ignatans , Sergei V. Kalinin , Vasiliki Tileli

Structural monitoring for complex built environments often suffers from mismatch between design, laboratory testing, and actual built parameters. Additionally, real-world structural identification problems encounter many challenges. For…

机器学习 · 计算机科学 2022-08-29 Xuyang Li , Hamed Bolandi , Talal Salem , Nizar Lajnef , Vishnu Naresh Boddeti

Cognitive diagnostic assessment aims to measure specific knowledge structures in students. To model data arising from such assessments, cognitive diagnostic models with discrete latent variables have gained popularity in educational and…

统计方法学 · 统计学 2023-08-25 Seunghyun Lee , Yuqi Gu

Structural equation modeling (SEM) is a prevalent approach for studying constructs.Traditionally, these constructs are modeled as reflectively measured latent variables - common factors that account for the variance-covariance structure of…

统计方法学 · 统计学 2026-04-02 Tamara Schamberger , Florian Schuberth , Jörg Henseler , Yves Rosseel

Discovering the complete set of causal relations among a group of variables is a challenging unsupervised learning problem. Often, this challenge is compounded by the fact that there are latent or hidden confounders. When only observational…

机器学习 · 计算机科学 2021-01-19 Anqi Liu , Hao Liu , Tongxin Li , Saeed Karimi-Bidhendi , Yisong Yue , Anima Anandkumar

We study the identification and estimation of structural parameters in dynamic panel data logit models where decisions are forward-looking and the joint distribution of unobserved heterogeneity and observable state variables is…

计量经济学 · 经济学 2018-05-11 Victor Aguirregabiria , Jiaying Gu , Yao Luo

Biological systems commonly exhibit complex spatiotemporal patterns whose underlying generative mechanisms pose a significant analytical challenge. Traditional approaches to spatiodynamic inference rely on dimensionality reduction through…

定量方法 · 定量生物学 2025-08-01 Jun Won Park , Kangyu Zhao , Sanket Rane

In this study, we present our methodology for two tasks: the Emotional Mimicry Intensity (EMI) Estimation Challenge and the Behavioural Ambivalence/Hesitancy (BAH) Recognition Challenge, both conducted as part of the 8th Workshop and…

计算机视觉与模式识别 · 计算机科学 2025-04-21 Tobias Hallmen , Robin-Nico Kampa , Fabian Deuser , Norbert Oswald , Elisabeth André

Multi-modal large language models (MLLMs), such as GPT-4o, excel at integrating text and visual data but face systematic challenges when interpreting ambiguous or incomplete visual stimuli. This study leverages statistical modeling to…

机器学习 · 计算机科学 2024-12-09 Ching-Yi Wang

Graph-structured data exhibit substantial heterogeneity in where their predictive signals originate: in some domains, node-level semantics dominate, while in others, structural patterns play a central role. This structure-semantics…

计算与语言 · 计算机科学 2026-04-03 Safal Thapaliya , Zehong Wang , Jiazheng Li , Ziming Li , Yanfang Ye , Chuxu Zhang

We study the problem of learning multi-index models (MIMs), where the label depends on the input $\boldsymbol{x} \in \mathbb{R}^d$ only through an unknown $\mathsf{s}$-dimensional projection $\boldsymbol{W}_*^\mathsf{T} \boldsymbol{x} \in…

统计理论 · 数学 2026-02-11 Hugo Latourelle-Vigeant , Theodor Misiakiewicz

This paper proposes a novel latent semantic learning method for extracting high-level features (i.e. latent semantics) from a large vocabulary of abundant mid-level features (i.e. visual keywords) with structured sparse representation,…

多媒体 · 计算机科学 2015-03-19 Zhiwu Lu , Yuxin Peng

A graphical model is a statistical model that is associated to a graph whose nodes correspond to variables of interest. The edges of the graph reflect allowed conditional dependencies among the variables. Graphical models admit…

统计方法学 · 统计学 2016-06-09 Mathias Drton , Marloes H. Maathuis

State-space models (SSM) are central to describe time-varying complex systems in countless signal processing applications such as remote sensing, networks, biomedicine, and finance to name a few. Inference and prediction in SSMs are…

统计计算 · 统计学 2022-10-26 Víctor Elvira , Émilie Chouzenoux

Personality traits are latent variables, and as such, are impossible to measure without the use of an assessment. Responses on the assessments can be influenced by both transient (state-related) error and measurement error, obscuring the…

应用统计 · 统计学 2017-06-02 Amy E. Nussbaum , Cornelis J. Potgieter , Michael Chmielewski

Empirical research in many social disciplines involves constructs that are not directly observable, such as behaviors. To model them, constructs must be operationalized using their relations with indicators. Structural equation modeling…

统计方法学 · 统计学 2025-07-30 Jonas Bauer , Axel Mayer , Christiane Fuchs , Tamara Schamberger