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Training deep neural networks requires datasets with a large number of annotated examples. The collection and annotation of these datasets is not only extremely expensive but also faces legal and privacy problems. These factors are a…

计算机视觉与模式识别 · 计算机科学 2025-01-17 Christoph Reinders , Frederik Schubert , Bodo Rosenhahn

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

图像与视频处理 · 电气工程与系统科学 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Pathology images are considered the ``gold standard" for cancer diagnosis and treatment, with gigapixel images providing extensive tissue and cellular information. Existing methods fail to simultaneously extract global structural and local…

计算机视觉与模式识别 · 计算机科学 2025-02-17 Haoming Luo , Xiaotian Yu , Shengxuming Zhang , Jiabin Xia , Yang Jian , Yuning Sun , Liang Xue , Mingli Song , Jing Zhang , Xiuming Zhang , Zunlei Feng

Recently, Mix-style data augmentation methods (e.g., Mixup and CutMix) have shown promising performance in various visual tasks. However, these methods are primarily designed for single-label images, ignoring the considerable discrepancies…

计算机视觉与模式识别 · 计算机科学 2023-11-28 Lei Wang , Yibing Zhan , Leilei Ma , Dapeng Tao , Liang Ding , Chen Gong

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

Data augmentation has become a de facto component of deep learning-based medical image segmentation methods. Most data augmentation techniques used in medical imaging focus on spatial and intensity transformations to improve the diversity…

图像与视频处理 · 电气工程与系统科学 2023-08-21 Berke Doga Basaran , Weitong Zhang , Mengyun Qiao , Bernhard Kainz , Paul M. Matthews , Wenjia Bai

Instance-level image classification tasks have traditionally relied on single-instance labels to train models, e.g., few-shot learning and transfer learning. However, set-level coarse-grained labels that capture relationships among…

机器学习 · 计算机科学 2023-11-21 Renyu Zhang , Aly A. Khan , Yuxin Chen , Robert L. Grossman

We introduce a novel method for overlaying cell type proportion data onto tissue images. This approach preserves spatial context while avoiding visual clutter or excessively obscuring the underlying slide. Our proposed technique involves…

计算机视觉与模式识别 · 计算机科学 2024-10-10 Lee Mason , Jonas Almeida

Neural networks are prone to overfitting and memorizing data patterns. To avoid over-fitting and enhance their generalization and performance, various methods have been suggested in the literature, including dropout, regularization, label…

计算机视觉与模式识别 · 计算机科学 2023-02-08 Humza Naveed , Saeed Anwar , Munawar Hayat , Kashif Javed , Ajmal Mian

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

计算机视觉与模式识别 · 计算机科学 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Multiple Instance Learning (MIL) has emerged as the best solution for Whole Slide Image (WSI) classification. It consists of dividing each slide into patches, which are treated as a bag of instances labeled with a global label. MIL includes…

计算机视觉与模式识别 · 计算机科学 2025-05-05 Ali Mammadov , Loic Le Folgoc , Julien Adam , Anne Buronfosse , Gilles Hayem , Guillaume Hocquet , Pietro Gori

Recently, pathological diagnosis has achieved superior performance by combining deep learning models with the multiple instance learning (MIL) framework using whole slide images (WSIs). However, the giga-pixeled nature of WSIs poses a great…

计算机视觉与模式识别 · 计算机科学 2024-10-31 Zijie Fang , Yifeng Wang , Ye Zhang , Zhi Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Despite their empirical success, neural networks still have difficulty capturing compositional aspects of natural language. This work proposes a simple data augmentation approach to encourage compositional behavior in neural models for…

计算与语言 · 计算机科学 2020-11-19 Demi Guo , Yoon Kim , Alexander M. Rush

We present a simple method, CropMix, for the purpose of producing a rich input distribution from the original dataset distribution. Unlike single random cropping, which may inadvertently capture only limited information, or irrelevant…

计算机视觉与模式识别 · 计算机科学 2022-06-01 Junlin Han , Lars Petersson , Hongdong Li , Ian Reid

Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…

计算机视觉与模式识别 · 计算机科学 2021-11-02 Zhuchen Shao , Hao Bian , Yang Chen , Yifeng Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Collecting fine-grained labels usually requires expert-level domain knowledge and is prohibitive to scale up. In this paper, we propose Attribute Mix, a data augmentation strategy at attribute level to expand the fine-grained samples. The…

计算机视觉与模式识别 · 计算机科学 2020-07-10 Hao Li , Xiaopeng Zhang , Hongkai Xiong , Qi Tian

This work presents a novel approach for selecting the optimal ensemble-based classification method and features with a primarly focus on achieving generalization, based on the state-of-the-art, to provide diagnostic support for Sickle Cell…

机器学习 · 计算机科学 2026-01-21 Nataša Petrović , Gabriel Moyà-Alcover , Antoni Jaume-i-Capó , Jose Maria Buades Rubio

Computational pathology involves the digitization of stained tissues into whole-slide images (WSIs) that contain billions of pixels arranged as contiguous patches. Statistical analysis of WSIs largely focuses on classification via multiple…

计算机视觉与模式识别 · 计算机科学 2026-03-24 So Won Jeong , Veronika Ročková

Augmentation for dense prediction typically relies on either sample mixing or generative synthesis. Mixing improves robustness but misaligned masks yield soft label ambiguity. Diffusion synthesis increases apparent diversity but, when…

计算机视觉与模式识别 · 计算机科学 2025-11-06 Pengyu Jie , Wanquan Liu , Rui He , Yihui Wen , Deyu Meng , Chenqiang Gao

Multiplex tissue immunostaining is a technology of growing relevance as it can capture in situ the complex interactions existing between the elements of the tumor microenvironment. The existence and availability of large, annotated image…

计算机视觉与模式识别 · 计算机科学 2021-03-09 Daniel Jiménez-Sánchez , Mikel Ariz , Carlos Ortiz-de-Solórzano